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Journals
Antioxidants
Special Issues
Sunscreens and Antioxidants
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Sunscreens and Antioxidants

A special issue of Antioxidants (ISSN 2076-3921).

Deadline for manuscript submissions: closed (30 October 2020) | Viewed by 11701

Special Issue Editors

Prof. Dr. Martina Meinke

E-Mail Website
Guest Editor
Center of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Venereology and Allergology, Charité—Universitätsmedizin Berlin, 10117 Berlin, Germany
Interests: skin antioxidants; oxidative stress; collagen–elastin index; radical scavenging activity; cutaneous carotenoids; reactive oxygen species; sun protection
Special Issues, Collections and Topics in MDPI journals
Dr. Silke Lohan

E-Mail Website1 Website2
Guest Editor
Charité–Universitätsmedizin Berlin, Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous Physiology, Charitéplatz 1, 10117 Berlin, Germany
Interests: oxidative stress; skin; antioxidants; redox status; nutrition; radical species; solar irradiation and its effect on skin; sun protection

Special Issue Information

Dear Colleagues,

Solar radiation is as essential for human life as it is important for the stimulation of vitamin D synthesis and well-being. However, an overly high dose of solar radiation leads to cell membrane and DNA damage and to the formation of free radicals such as reactive oxygen species (ROS). Ultra-violet (UV) irradiation can be blocked due to the chemical and physical filters contained in sunscreens. The use of UV-absorbing sunscreens with high SPF tempts consumers to extend their exposure to the sun by several hours without considering that they are not protected in the visible (VIS) and near-infrared (NIR) spectral regions. For these regions, no filters are available. In the VIS spectral region, sunscreen formulations containing filters would color the skin of applicants. VIS/NIR irradiation accounts for ~40% of all free radicals that are formed during sun irradiation; the remaining ~60% are formed by UV light. ROS need to be tightly controlled in order to prevent their uncontrolled accumulation in the cell; otherwise, they are harmful to metabolic processes and cell structures. The planned Special Issue "Sunscreens and Antioxidants " will focus on the importance of sun protection in the whole spectral range with regard to the prevention of oxidative stress and its biological consequences.

Prof. Dr. Martina Meinke
Dr. Silke Lohan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Prevent any sun damage
  • Visible light
  • IR light
  • UV filters
  • Full spectrum sun protection
  • Sun damage
  • Hair
  • Skin
  • Mineral coatings
  • Physical filters
  • Reactive oxygen species.

Published Papers (2 papers)

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Research

16 pages, 3761 KiB  
Article
Sinapic Acid Esters: Octinoxate Substitutes Combining Suitable UV Protection and Antioxidant Activity
by Cédric Peyrot, Matthieu M. Mention, Fanny Brunissen and Florent Allais
Antioxidants 2020, 9(9), 782; https://0-doi-org.brum.beds.ac.uk/10.3390/antiox9090782 - 24 Aug 2020
Cited by 30 | Viewed by 5733
Abstract
In 2021, Hawaii will permanently ban the use and sale of octinoxate-based sunscreens as studies have shown serious impacts of such UV filters on the coral reef. This ban, which could be generalized to other countries, highlights the extreme need to offer alternative [...] Read more.
In 2021, Hawaii will permanently ban the use and sale of octinoxate-based sunscreens as studies have shown serious impacts of such UV filters on the coral reef. This ban, which could be generalized to other countries, highlights the extreme need to offer alternative UV filters that are not only effective in terms of sun protection, but also healthy with regards to human health and the environment. In this context, a wide library of p-hydroxycinnamic esters deriving from naturally occurring sinapic acid has been synthesized using a Knoevenagel–Doebner condensation. The UV filtering activities as well as the antioxidant properties of these sinapic acid esters were then investigated. The results showed promising UVB protection and antioxidant efficacy. A Structure–Activity Relationship (SAR) study on the sinapic acid esters highlighted the need of a free phenol to, as expected, observe antioxidant activity, but also to obtain a higher intensity of protection. Moreover, the nature of the ester moiety also proved to be a key structural feature for the UV absorbance, as higher steric hindrance on the ester moiety leads to more active compounds. The judicious structural design of sinapic esters thus provides promising compounds combining UV protection and antioxidant activity. Full article
(This article belongs to the Special Issue Sunscreens and Antioxidants)
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14 pages, 2638 KiB  
Article
Sustainable Synthesis of p-Hydroxycinnamic Diacids through Proline-Mediated Knoevenagel Condensation in Ethanol: An Access to Potent Phenolic UV Filters and Radical Scavengers
by Benjamin Rioux, Cédric Peyrot, Matthieu M. Mention, Fanny Brunissen and Florent Allais
Antioxidants 2020, 9(4), 331; https://0-doi-org.brum.beds.ac.uk/10.3390/antiox9040331 - 18 Apr 2020
Cited by 22 | Viewed by 5267
Abstract
p-Hydroxycinnamic diacids are reaction intermediates of the classical Knoevenagel–Doebner condensation between malonic acid and benzaldehydes. As they are generally obtained in low yields, they remain relatively under-studied and under-exploited. Herein, we developed and optimized a sustainable synthetic procedure allowing the production of [...] Read more.
p-Hydroxycinnamic diacids are reaction intermediates of the classical Knoevenagel–Doebner condensation between malonic acid and benzaldehydes. As they are generally obtained in low yields, they remain relatively under-studied and under-exploited. Herein, we developed and optimized a sustainable synthetic procedure allowing the production of these compounds in good to high yields (60–80%) using proline as the catalyst and ethanol as the solvent. Study of their antioxidant and anti-UV activities revealed that these p-hydroxycinnamic diacids were not only potent radical scavengers but also efficient UV filters exhibiting high photostability. Full article
(This article belongs to the Special Issue Sunscreens and Antioxidants)
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