Special Issues

Biomedicines runs special issues to create collections of papers on specific topics. The aim is to build a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors who are experts in the subject and oversee the editorial process for papers. Papers published in a Special Issue will be collected together on a dedicated page of the journal website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Contribution of Epigenetics to Normal and Malignant Hematopoiesis
edited by
submission deadline 31 Jan 2022 | 2 articles | Viewed by 1431
Keywords: epigenetics; chromatin modifiers; DNA (hydroxy)methylation; histone modification; hematopoietic stem cells; self-renewal; differentiation; hematological malignancies; molecular mechanisms; epigenetic therapy
(This special issue belongs to the Section Cell Biology and Pathology)
Non-invasive Biomarkers in Biologic Therapy for Oncology and Chronic Inflammation
edited by
submission deadline 31 Jan 2022 | Viewed by 180
Keywords: immunotherapy; personalized medicine; prognosis markers
(This special issue belongs to the Section Cancer Biology and Therapeutics)
Apoptosis—50 Years after Its Discovery
edited by Cecilia M. P. Rodrigues and Fernando Capela e Silva
submission deadline 31 Jan 2022 | 1 articles | Viewed by 1271
(This special issue belongs to the Section Cell Biology and Pathology)
Immune Landscape in Neurodegenerative Diseases
edited by , and Marco Cosentino
submission deadline 31 Jan 2022 | Viewed by 278
Keywords: neurodegenerative disorders; neuroinflammation; central and peripheral immune system; microglia; astrocytes; ependydimal cells; BBB; BCSFB; DAMPs; mast cells; neutrophils; basophils; monocytes; macrophages; dendritic cells; NK cells; T cells
(This special issue belongs to the Section Immunology and Immunotherapy)
Pharmacomicrobiomics in Non-communicable Disease
edited by
submission deadline 31 Jan 2022 | 8 articles | Viewed by 7235
Keywords: Microbiome; Cell signaling; Molecular pathway; Cancers; Chronic disorders; Heart disease; Inflammation; Immune response
(This special issue belongs to the Section Drug Discovery)
Cancer: Immunology and Immunotherapy
edited by and Rajesh Singh
submission deadline 31 Jan 2022 | 1 articles | Viewed by 1423
Keywords: immunotherapy; nano-immunology; cancer immunology; tumor-immune microenvironment; immuncheckpoint inhibitors
(This special issue belongs to the Section Immunology and Immunotherapy)
Liver Fibrosis: Molecular Mechanisms, Potential Therapeutic Targets and Clinical Biomarkers
edited by
submission deadline 31 Jan 2022 | 1 articles | Viewed by 388
Keywords: liver; fibrosis; treatment; therapeutic target; biomarker; hepatitis; NAFLD; NASH; MAFLD; HSC; GPCR; immunity; cell death
(This special issue belongs to the Section Cancer Biology and Therapeutics)
Molecular Mechanisms of Bone Metastases in Biomedicines submission deadline 31 Jan 2022 | 2 articles | Viewed by 1891
Keywords: Bone metastases; Cancer stem cells; Tumour invasion; EMT/MET; Osteolysis; Dormancy; Bone remodeling; Pre-metastatic niche; Therapeutic target; Tumour microenvironment; Tumor– stroma crosstalk
(This special issue belongs to the Section Cancer Biology and Therapeutics)
Testicular Disorders and Infertility: From Pathophysiologic Mechanisms to Therapeutic Strategies
edited by Carmelo Romeo
submission deadline 31 Jan 2022 | Viewed by 260
Keywords: cryptorchidism; varicocele; torsion of the testes; disorders of sexual development
(This special issue belongs to the Section Molecular and Translational Medicine)
Aging, Inflammaging and Multimorbidity: What Is the Role of Endothelial Dysfunction?
edited by Giuseppina Basta and Serena Del Turco
submission deadline 31 Jan 2022 | 2 articles | Viewed by 1504
Keywords: aging; inflammaging; vascular disease; frailty; oxidative stress; endothelial dysfunction; comorbidity; autophagy; cellular senescence
(This special issue belongs to the Section Cell Biology and Pathology)
Alternative Splicing and Cancer
edited by Kenji Ohe and
submission deadline 31 Jan 2022 | Viewed by 222
Keywords: alternative splicing; circular RNA; drug resistance; RNA metabolism; non-coding RNA
(This special issue belongs to the Section Cancer Biology and Therapeutics)
Gastric Cancer: From Mechanisms to Therapeutic Approaches
edited by
submission deadline 31 Jan 2022 | 1 articles | Viewed by 1110
Keywords: gastric cancer; tumor microenvironment; therapeutic vulnerability; molecular subtype
(This special issue belongs to the Section Cancer Biology and Therapeutics)
30 Years of Alternative Macrophage Activation—a Simple Complexity
edited by
submission deadline 31 Jan 2022 | 1 articles | Viewed by 1410
Keywords: macrophage; monocyte; inflammation; cancer; cytokine; atherosclerosis; infection; healing; tolerance
(This special issue belongs to the Section Immunology and Immunotherapy)
Regenerative Ophthalmology: From Molecular Basis to Therapy
edited by Frederic Michon
submission deadline 31 Jan 2022 | Viewed by 192
Keywords: ophthalmology; physiopathology; retina; optic nerve; iris; lens; cornea; tear film; single-cell -omics; gene therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Conformational Dynamics of Viral Proteins
edited by
submission deadline 31 Jan 2022 | 3 articles | Viewed by 3122
Keywords: spike protein; polymerase; reverse transcriptase; integrase; corona; flu; HIV
(This special issue belongs to the Section Cell Biology and Pathology)
State-of-the-Art on Gastrointestinal Cancers in Italy submission deadline 31 Jan 2022 | Viewed by 175
Keywords: colorectal cancer; gastric cancer; esophageal cancer; biomarkers; microbiota; liquid biopsy
(This special issue belongs to the Section Cancer Biology and Therapeutics)
Bioengineered In Vitro Models for Biomedical Applications submission deadline 31 Jan 2022 | 9 articles | Viewed by 9140
Keywords: biomaterials; in vitro models; organ-on-chip; scaffolds; tissue barriers; hydrogels; tissue engineering; 3D printing; microfabrication; tissue microenvironment
(This special issue belongs to the Section Biomedical Engineering in Human Health)
Beta Amyloid: Synaptic Regulation and Dysregulation
edited by and Guendalina Olivero
submission deadline 31 Jan 2022 | Viewed by 141
Keywords: beta amyloid; aducanumab; amyloid neutralizing antibodies; ARIA; Alzheimer’ s disease; synaptic modulation
(This special issue belongs to the Section Neurobiology and Neurologic Disease)
Translational Research in Shock Wave Medicine
edited by Yao-Chi Chuang and
submission deadline 31 Jan 2022 | 6 articles | Viewed by 2854
Keywords: shock wave; medicine; tissue regeneration; anti-inflammation; drug delivery
(This special issue belongs to the Section Molecular and Translational Medicine)
Oncoimmunity and Immunotherapy in Solid Tumors
edited by
submission deadline 31 Jan 2022 | 6 articles | Viewed by 1838
Keywords: cancer immunity; immunotherapy; immunosuppressive tumor microenvironment; tumor– immune cell interaction; tumor vaccine; checkpoint blockade; immunoadjuvant
(This special issue belongs to the Section Immunology and Immunotherapy)
30 Years of OPN Milestones and Future Avenues submission deadline 31 Jan 2022 | 5 articles | Viewed by 3325
Keywords: osteopontin; inflammation; autoimmunity; biomarker; cancer; therapeutics
(This special issue belongs to the Section Molecular and Translational Medicine)
Omics Data Analysis and Integration in Complex Diseases
edited by Pedro Carmona-Sáez and Daniel Toro-Domínguez
submission deadline 31 Jan 2022 | 3 articles | Viewed by 2256
Keywords: Omics Data Analysis; Omics data integration; Biomarker Discovery; Disease Classification; Precision Medicine; Machine Learning; Bioinformatics; Biostatistics
(This special issue belongs to the Section Molecular and Translational Medicine)
The Wnt Signaling Pathway in Cancers
edited by
submission deadline 31 Jan 2022 | Viewed by 103
Keywords: wnt; cancer; drug resistance; therapy; microenvironment; self-renewal; differentiation
(This special issue belongs to the Section Cell Biology and Pathology)
Pharmacology and Pharmacokinetics of Cancer Drugs
edited by Sukyung Woo, and
submission deadline 31 Jan 2022 | Viewed by 246
Keywords: Pharmacokinetics; Pharmacodynamics; Quantitative pharmacology; Model-informed drug development; Drug interactions; Cellular pharmacology; Sub-cellular distribution and drug delivery; Drug transport; System/mechanistic and/or population modeling; Physiologically based PK modeling
(This special issue belongs to the Section Drug Metabolism)
Non-antiviral Agents for Treatment of COVID-19
edited by
submission deadline 31 Jan 2022 | Viewed by 169
Keywords: COVID-19; antiviral agents; cytokines; tissue-protective factors; moderate-to-severe pneumonia
(This special issue belongs to the Section Drug Discovery)
Advances Research in Traumatic Encephalopathy
edited by Brandon Lucke-Wold
submission deadline 31 Jan 2022 | 2 articles | Viewed by 2245
Keywords: traumatic brain injury; traumatic encephalopathy; mild traumatic brain injury; severe traumatic brain injury; closed or penetrating head injury; treatment advances
(This special issue belongs to the Section Neurobiology and Neurologic Disease)
Advances in Tumor Angiogenesis and Lymphangiogenesis
edited by
submission deadline 31 Jan 2022 | Viewed by 214
(This special issue belongs to the Section Cell Biology and Pathology)
Nonsense-Mediated mRNA Decay: From Molecular Mechanism to Therapeutic Perspectives
edited by Fabrice Lejeune
submission deadline 31 Jan 2022 | 3 articles | Viewed by 2011
Keywords: Premature termination codon; Nonsense-mediated mRNA decay; mRNA decay; UPF proteins; SMG proteins; Exon junction complex; P-bodies; Pioneer round of translation; Gene expression and regulation; Human genetic diseases
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Glioma Metabolism, Epigenetics, and Microenvironment
edited by L. Eric Huang and
submission deadline 31 Jan 2022 | Viewed by 249
Keywords: DNA methylation; epigenetics; glioma; histone modification; isocitrate dehydrogenase; metabolism; microenvironment
(This special issue belongs to the Section Cancer Biology and Therapeutics)
Targeting Myeloid Cells to Shape Tumor
edited by Dorothée Duluc
submission deadline 31 Jan 2022 | Viewed by 97
Keywords: dendritic cells; macrophages; neutrophils; MDSC; tumor immunity; immunotherapies; TME
(This special issue belongs to the Section Cell Biology and Pathology)
Paradigm Shift: From Genetics to Epigenetics 2.0
edited by
submission deadline 31 Jan 2022 | Viewed by 139
Keywords: epigenetics; ontogenesis; stem cell differentiation; endocrine disruptors; nutrigenetics; nutrigenomics; microbioma; microbiota
(This special issue belongs to the Section Cell Biology and Pathology)
Origins of Inter-individual Variability in Neuropsychiatric Disorders
edited by
submission deadline 31 Jan 2022 | Viewed by 139
Keywords: inter-individual variability; psychiatric disorders; neurological disorders; brain activity; heterogeneity; normative modeling; neuroimaging; biomarkers; biological mechanism
(This special issue belongs to the Section Neurobiology and Neurologic Disease)
Recent Advances in the Discovery of Novel Drugs on Natural Molecules submission deadline 15 Feb 2022 | 17 articles | Viewed by 18364
Keywords: natural compounds; bioactive peptides; peptidomimetics; microbial metabolites; polyphenols; genome mining; molecular modeling; therapeutic uses
(This special issue belongs to the Section Drug Discovery)
Internal Diseases Complicating Pregnancy: Pathogenesis and Treatment
edited by
submission deadline 15 Feb 2022 | Viewed by 260
Keywords: cardiovascular disease; hypertension; renal diseases and pregnancy; hypertension in pregnancy; diabetes mellitus; metabolic syndrome; thyroid diseases; other endocrine disorders in pregnant women; epilepsy and myasthenia gravis; SM; and other neurological problems in reproduction and pregnancy; gastroenterological diseases— Crohn's disease; colitis ulcerosa; liver diseases; diagnosis and treatment; new therapies; pathogenesis
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Mechanisms in Lysosomal Storage Diseases: From Pathogenesis to Therapeutic Strategies submission deadline 15 Feb 2022 | 6 articles | Viewed by 6729
Keywords: lysosomal storage disorders; novel therapies for genetic diseases; molecular diagnosis; biomarkers; substrate storage; autophagy; cell signaling; molecular mechanisms of genetic disorders; neurodegeneration; metabolic diseases
(This special issue belongs to the Section Cell Biology and Pathology)
Key Processes in Health and Disease Regulated by the Hippo Pathway
edited by
submission deadline 15 Feb 2022 | 1 articles | Viewed by 1430
(This special issue belongs to the Section Cell Biology and Pathology)
Targeted Therapies for Cancer submission deadline 15 Feb 2022 | 8 articles | Viewed by 7229
Keywords: cancer; targeted therapies; tumor-associated antigens; monoclonal antibodies; small molecule inhibitors; immunotoxins; targeted nano-delivery systems
(This special issue belongs to the Section Cancer Biology and Therapeutics)
Autoimmune Regulator (AIRE) Gene in the Pathogenesis of Autoimmune Diseases
edited by Rachid Tazi-Ahnini
submission deadline 15 Feb 2022 | 1 articles | Viewed by 1100
Keywords: autoimmune regulator (AIRE); autoimmune disease; thymic selection; tissue-restricted antigens
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Early Biological Reactions on Biomaterials Determining Long-Term Tissue Regeneration Effects submission deadline 15 Feb 2022 | 6 articles | Viewed by 4635
Keywords: biomaterial; early interactions; homeostasis; angiogenesis; cytokines; material science
(This special issue belongs to the Section Biomedical Materials)
Telomerase: Role in Health and Aging
edited by Yegor E. Yegorov
submission deadline 15 Feb 2022 | 8 articles | Viewed by 6301
Keywords: telomerase; telomeres; SASP; redox regulation; non-canonical functions of telomerase; inflamm-aging; senolytics; cancer; lifespan; healthspan; telomeropathies; G4 structures
(This special issue belongs to the Section Gene and Cell Therapy)
Anti-angiogenesis Therapeutics in Cancer, Ocular and Skin Disorders
edited by
submission deadline 15 Feb 2022 | 3 articles | Viewed by 2285
Keywords: Angiogenesis and anti-angiogenesis in hematological malignancies; angiogenesis and lymphogenesis in cancer (tumor growth; invasion; and metastasis); survey of different anti-angiogenesis strategies; angiogenesis and anti-angiogenesis in eye diseases; angiogenesis and anti-angiogenesis in nonmalignant skin disorders; integrin in angiogenesis and lymphogenesis; anti-VEGF (vascular endothelial growth factor) in angiogenesis modulation and cancer therapy; tyrosine kinase inhibitors (TKI) in angiogenesis modulation and cancer therapy; multitargeted anti-angiogenesis therapy in cancer therapy; micro-RNA and angiogenesis modulation; naturally occurring anti-angiogenesis agents; angiogenesis biomarkers and impact on personalized management; combination of anti-angiogenesis and chemotherapeutics; nanotechnology in enhancing the utility of anti-angiogenesis agents— combinations with standard anti-cancer; nano-targeted anti-angiogenesis agents in cancer detection; diabetic retinopathy (DR); age-related macular degeneration (AMD); dermatological disorders; rosacea; poikiloderma; and psoriasis
(This special issue belongs to the Section Cell Biology and Pathology)
Biomarkers in Neurodegenerative Diseases 2.0
edited by
submission deadline 15 Feb 2022 | 10 articles | Viewed by 8603
Keywords: neurodegenerative diseases; disease mechanisms; biomarkers; disease management; diagnosis; experimental medicine
(This special issue belongs to the Section Neurobiology and Neurologic Disease)
Molecular Research of Alzheimer's Disease
edited by
submission deadline 15 Feb 2022 | 9 articles | Viewed by 8680
(This special issue belongs to the Section Neurobiology and Neurologic Disease)
Approaches to Fight Microbial Infection-Related Biofilms submission deadline 15 Feb 2022 | 3 articles | Viewed by 2834
Keywords: regulatory networks governing biofilms; antibiotic resistance; virulence; drug targets; omics technologies; quorum sensing; antibiofilm agents; natural antimicrobials
(This special issue belongs to the Section Drug Discovery)
Pharmacokinetics and Therapeutic Drug Monitoring
edited by
submission deadline 15 Feb 2022 | 8 articles | Viewed by 5379
Keywords: therapeutic drug monitoring; pharmacokinetics; drug; blood levels; microsampling; analytical methods
(This special issue belongs to the Section Drug Metabolism)
Liquid Biopsies in Cancer Diagnosis, Monitoring and Prognosis submission deadline 15 Feb 2022 | 7 articles | Viewed by 8967
(This special issue belongs to the Section Molecular and Translational Medicine)
Roles of Endoplasmic Reticulum Stress in Immune Responses
edited by
submission deadline 18 Feb 2022 | 1 articles | Viewed by 1369
Keywords: ER stress; unfolded protein response; IRE1; PERK; ATF6; XBP1s; ATF4; immune responses
(This special issue belongs to the Section Immunology and Immunotherapy)
Advanced Research in Cell Motility
edited by Daniel Zicha
submission deadline 18 Feb 2022 | 6 articles | Viewed by 5315
Keywords: migration; chemotaxis; cell extension; cell retraction; quantitative phase imaging; time lapse
(This special issue belongs to the Section Cell Biology and Pathology)
Nutraceuticals in Disease Prevention
edited by
submission deadline 18 Feb 2022 | 3 articles | Viewed by 2427
Keywords: clinical nutrition; nutraceuticals; health promotion; detoxification; metabolism; prevention; chemoprevention
(This special issue belongs to the Section Molecular and Translational Medicine)
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