Eosinophilic Inflammation
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 15043
Special Issue Editors
Interests: allergy; allergic rhinitis; asthma; eosinophils
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
The focus of this Special Issue is eosinophilic inflammation such as allergic rhinitis, asthma, chronic rhinosinusitis with nasal polyp, esophagitis, gastroenteritis, and otitis media.
Eosinophils are key contributors to Th2-associated pathologies such as allergic disorders. They also function as effectors in the innate immune response through the expression of Toll-like receptors. In the inflamed site, activated eosinophils exert their effects through cytotoxic mediators, comprising granules (EPO, MBP, ECP, and EDN), cytokines, chemokines, and lipid mediators, resulting in tissue damage. However, little is known about the mechanisms of pathogenesis by activated eosinophils.
Here, we focus not only all clinical investigations involved in eosinophils-derived disorders but also basic on investigations in vitro and in vivo using animal models.
Prof. Dr. Akira Kanda
Dr. David Dombrowicz
Guest Editors
Manuscript Submission Information
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Keywords
- airway inflammation
- allergic rhinitis
- asthma
- chronic rhinosinusitis with nasal polyp
- eosinophil
- esophagitis
- gastroenteritis
- otitis media
- united airway disease
- atopic dermatitis
- airway hyperresponsiveness (AHR)