Epigenetic Mechanisms and Aging: Model Organism Drosophila

Dear Colleagues,

Cells have many pathways during the life of an organism: proliferate or die, differentiate or divide, etc. Cells also age and lose the ability to function. The fundamental question as to why this happens is complex, but it is clear that this process can be reversed in some instances. Drosophila melanogaster, or fruit fly, is a model organism with a long history of great contributions to science. As technology has progressed, the great genetic techniques have expanded to incorporating genome editing and many other advances. The short life cycle and conserved cellular processes make Drosophila an ideal model to investigate cellular behavior, especially for cellular pathways in vivo.

We hope that this Special Issue will bring together science utilizing the latest advancements and breakthroughs in cellular aging and behavior. We are looking for investigations and reviews on a wide-ranging list of topics, including signal transduction, cell migration, morphogenesis, homeostasis, polarity and adhesion, especially as these relate to adult tissues.

Dr. Nicholas Tolwinski
Guest Editor

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• drosophila melanogaster
• model organism
• cell biology
• developmental biology
• genetics
• molecular biology
• cell signaling
• cellular differentiation
• cell proliferation
• cell cycle
• cellular morphogenesis
• cell-cell communication
• stem cells
• cell migration
• apoptosis
• cytoskeleton
• cell adhesion
• cellular metabolism
• functional genomics
• CRISPR/Cas9 in drosophila
• omics technologies
• disease models
• drug discovery
• regeneration
• genetic screens
• cellular stress responses