Cellular Protection and Regeneration in Age-Related Diseases of the Retina

Dear Colleagues,

The retina is a central nervous system tissue that carries out the remarkable task of converting photons of light into complex signals to the visual cortex to create high-resolution images of our surrounding environment. There are 8 major cell types in the retina, each possessing a highly specialized structure and function, and a few of these cell types are affected in retinal diseases. The retina is susceptible to several age-related diseases, including age-related macular degeneration, glaucoma, and diabetic retinopathy.

While there are currently surgical and pharmacological treatments for these diseases, they only temporarily minimize symptoms or slow disease progression, but none prevent or eradicate these diseases. There are promising potential therapies on the horizon, but more research and development needs to be done to arrive at a cure. Research areas that offer promise for retinal diseases include reducing oxidative stress, modifying inflammatory signaling, and maintaining metabolic homeostasis and cell transplant/replacement.

The goal of this Special Issue is to highlight current multidisciplinary approaches and developments in the field of age-related diseases of the retina including pharmacology, drug delivery, and cell replacement to combat retinal cell pathology.

Dr. Raymond Scott Duncan
Guest Editor

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• Retina
• Vision
• Cellular signaling
• Age-related macular degeneration
• Glaucoma
• Oxidative stress
• Inflammation
• Retinal ganglion cells
• Photoreceptors
• Retinal pigment epithelium