Recent Advances in Quartz Crystal Microbalance-Based Sensor Applications: Part II

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Applied Chemical Sensors".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 4470

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Kalsruhe Institute of Technology, Institute of Functional Interfaces, Chemistry of oxydic and organic Interfaces, Hermann-von-Helmholtz-Platz 1, Geb. 330, R. 324, 76344 Eggenstein-Leopoldshafen, Germany
Interests: organic; inorganic; semiconducting thin film interfaces and their application to electronic devices, such as QCM based electronic nose/tongue applications using SURMOF sensor arrays in gas/liquid interfaces
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Dear Colleagues,

There has been a rapid increase in the number of publications related to QCM sensing applications during the last few decades. They have been extensively used in deposition rate monitoring for controlling thickness in many deposition techniques, such as thermal vapor deposition, sputtering, and electrochemical deposition. QCMs have recently been used in many other applications in various disciplines of science and technology for the detection of vapors, volatile organic compounds (VOCs), environmental pollutants, biomolecules, disease biomarkers, cells, and pathogens in many different environments, including vacuums.

Recent advances in high-frequency QCMs allow us to measure the mass change in analytes adsorbed on modified QCM surfaces around pg/cm2 sensitivities. Among many other analytical techniques, QCM provides one of the most promising sensor technologies based on its low cost, rapid response, portability, nonhazardous label-free real-time procedure, and high sensitivity, which is ideal for the sensitive detection of analytes for next-generation sensors such as chemical sensing, including electronic nose, electronic tongue, microfluidic devices, lab-on-a-chip, single molecule sensing, nanosensors, medical analyzers, enzyme sensors, drugs, and medicodiagnostic testing.

This Special Issue of Chemosensors is dedicated to the discussion of the state of the art in QCM sensors with challenging material-coating techniques not only for gas/liquid phase and biosensing, but also for primary industries such as agriculture and aquatic products in industry.

Prof. Dr. Salih Okur
Guest Editor

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Keywords

  • QCM-based gas sensors
  • electrochemical quartz crystal microbalance (EQCM)
  • QCM-based sensors with biofunctional materials and food inspection
  • application of QCM for medical diagnosis
  • protein immobilization, cell attachment, cell adhesion
  • drug discovery and complex biopolymeric/biomolecular systems
  • QCM-based biosensors modified with molecular imprinted polymers
  • quartz crystal microbalance with dissipation monitoring analysis using QCM/QCM-D
  • chiral recognition, odor classification, and composition analysis
  • multichannel QCM array systems, QCM-based electronic nose, and electronic tongues

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Published Papers (2 papers)

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Research

8 pages, 1951 KiB  
Communication
Methods for Calibrating the Electrochemical Quartz Crystal Microbalance: Frequency to Mass and Compensation for Viscous Load
by Claes-Olof A. Olsson, Anna Neus Igual-Muñoz and Stefano Mischler
Chemosensors 2023, 11(8), 456; https://0-doi-org.brum.beds.ac.uk/10.3390/chemosensors11080456 - 14 Aug 2023
Viewed by 1187
Abstract
The main output from an Electrochemical Quartz Crystal Microbalance is a frequency shift. This note describes how to separate the mass- and viscous load contributions to this shift by a calibration procedure. The mass calibration is made by electroplating from a copper sulfate [...] Read more.
The main output from an Electrochemical Quartz Crystal Microbalance is a frequency shift. This note describes how to separate the mass- and viscous load contributions to this shift by a calibration procedure. The mass calibration is made by electroplating from a copper sulfate solution in ethanol/water with 100% current efficiency. An estimate of viscous load is obtained by measuring the energy dissipation and is related to frequency change using the Kanazawa–Gordon equation. Two approaches are discussed: either by performing calibration experiments in a series of water–glycerol mixtures or by following oscillations in frequency and dissipation by collecting data during the stabilization phase of the experiment. Full article
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12 pages, 8089 KiB  
Article
Real-Time Detection of the Bacterial Biofilm Formation Stages Using QCM-Based Sensors
by Jordi Salazar, Miquel-Àngel Amer, Antoni Turó, Nagore Castro, Marc Navarro, Sara Soto, Yaiza Gabasa, Yuly López and Juan-Antonio Chávez
Chemosensors 2023, 11(1), 68; https://0-doi-org.brum.beds.ac.uk/10.3390/chemosensors11010068 - 14 Jan 2023
Cited by 4 | Viewed by 1987
Abstract
Bacterial biofilms are a major cause of harm related to medical infections and biofouling. Thus, 80% of total infections are caused by biofilm-forming microorganisms. Consequently, knowledge of biofilm formation stages is crucial to develop effective treatments to prevent their formation in medical implants, [...] Read more.
Bacterial biofilms are a major cause of harm related to medical infections and biofouling. Thus, 80% of total infections are caused by biofilm-forming microorganisms. Consequently, knowledge of biofilm formation stages is crucial to develop effective treatments to prevent their formation in medical implants, tools, and devices. For this purpose, quartz crystal microbalance (QCM) sensors are becoming a good alternative to analytical methods for the real-time monitoring of bacterial growth in liquid media culture. In a previous paper, the authors described an affordable multi-channel measurement instrument based on QCM sensors. However, in order to validate its correct operation, complementary experimental measurements based on bacterial biofilm growth were performed. In this work, the experimental measurements that allow the identification of the different biofilm formation stages are described. The results obtained are discussed. Full article
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