Advanced Coatings for Biomedical Applications

A special issue of Coatings (ISSN 2079-6412). This special issue belongs to the section "Bioactive Coatings and Biointerfaces".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 8860

Special Issue Editors


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Guest Editor
Institute of Solid State Physics, Bulgarian Academy of Sciences, 1784 Sofia, Bulgaria
Interests: crystal growth; crystal structure; phase transitions; biomedical optics; X-ray diffraction; neutron diffraction; chemical vapor deposition

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Guest Editor
Institute of Electronics, Bulgarian Academy of Sciences, 72 Tzarigradsko Chaussee blvd., 1784 Sofia, Bulgaria
Interests: transition metal nitride coatings; titanium and its alloys; aluminum and its alloys; intermetallics; thin film deposition; surface modification; electron-beam surface processing; PVD technologies; materials characterization; X-ray diffraction

Special Issue Information

Dear Colleagues,

It is our pleasure to announce the Special Issue “Advanced Coatings for Biomedical Applications”, which will be published in the journal Coatings. It will serve as an international medium for discussion of topics contributing to a better understanding of the formation, characterization, and modeling of thin films and coatings for modern biomedicine, including but not limited to nitrides, oxides, oxynitrides, intermetallics, polymers, and others.

This Special Issue aims to collect articles discussing the topics related to the application formation of surface coatings using Physical Vapor Deposition (PVD), Chemical Vapor Deposition (CVD), and other methods. Manuscripts discussing the surface structures formed by different treatment techniques (e.g., laser beam, electron beam, etc.) with enhanced functional properties for biomedical applications, as well as the modeling of the processes, are also welcome. We invite you to submit a manuscript; full papers, communications, and reviews are welcome.

The scope of this Special Issue will serve as a forum for papers on the following concepts:

  • Thin film and coating deposition;
  • Biocompatibility;
  • Antibacterial properties;
  • Corrosion properties;
  • Mechanical properties.

Prof. Dr. Marin Gospodinov
Dr. Stefan Valkov
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Coatings is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • coatings for biomedical applications
  • nitride coatings
  • oxide coatings
  • intermetallic coatings
  • polymeric coatings

Published Papers (4 papers)

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Research

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12 pages, 2336 KiB  
Article
Synthesis and Characterization of Ti-Ta-Shape Memory Surface Alloys Formed by the Electron-Beam Additive Technique
by Maria Ormanova, Dimitar Dechev, Nikolay Ivanov, Geanina Mihai, Marin Gospodinov, Stefan Valkov and Marius Enachescu
Coatings 2022, 12(5), 678; https://0-doi-org.brum.beds.ac.uk/10.3390/coatings12050678 - 15 May 2022
Cited by 6 | Viewed by 1767
Abstract
The electron-beam cycling additive technique was proposed for the formation of shape memory Ti-Ta coatings on titanium substrate. On a commercially pure Ti plate, Ta film with a thickness of about 4 μm was deposited by direct current (DC) magnetron sputtering. The sample [...] Read more.
The electron-beam cycling additive technique was proposed for the formation of shape memory Ti-Ta coatings on titanium substrate. On a commercially pure Ti plate, Ta film with a thickness of about 4 μm was deposited by direct current (DC) magnetron sputtering. The sample was then subjected to an electron-beam surface alloying by a scanning electron beam. On the already-formed Ti-Ta surface alloy, a Ta coating with the same thickness was further deposited and the specimen was again subjected to electron-beam alloying for the second cycle. The same procedure was repeated for the third cycle. The structure obtained after each cycle Ti-Ta coatings was studied by X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), and Energy-dispersive X-ray spectroscopy (EDX). The Young’s modulus, hardness, and shape memory effect (SME) were studied by nanoindentation experiments. The results showed that the thickness of the Ti-Ta coatings is about 50 μm in all cases, where the Ta content increases after each technological cycle. It was found that the obtained phase composition is in the form of a double-phase structure of α’ martensitic and β phases, where the highest amount of beta is registered in the case of the Ti-Ta coating obtained after the third cycle. The results obtained for the Young’s modulus and hardness showed that both mechanical characteristics decrease significantly after each cycle. Additionally, the elastic depth recovery ratio increases with an increase in the number of cycles. Full article
(This article belongs to the Special Issue Advanced Coatings for Biomedical Applications)
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13 pages, 2040 KiB  
Article
Duplex Surface Modification of 304-L SS Substrates by an Electron-Beam Treatment and Subsequent Deposition of Diamond-like Carbon Coatings
by Stanislava Rabadzhiyska, Georgi Kotlarski, Maria Shipochka, Peter Rafailov, Maria Ormanova, Velichka Strijkova, Nina Dimcheva and Stefan Valkov
Coatings 2022, 12(3), 401; https://0-doi-org.brum.beds.ac.uk/10.3390/coatings12030401 - 18 Mar 2022
Cited by 5 | Viewed by 2341
Abstract
In this study, we present the results of the effect of duplex surface modification of 304-L stainless steel substrates by an electron-beam treatment (EBT) and subsequent deposition of diamond-like carbon coatings on the surface roughness and corrosion behavior. During the EBT process, the [...] Read more.
In this study, we present the results of the effect of duplex surface modification of 304-L stainless steel substrates by an electron-beam treatment (EBT) and subsequent deposition of diamond-like carbon coatings on the surface roughness and corrosion behavior. During the EBT process, the beam power was varied from 1000 to 1500 W. The successful deposition of the DLC coatings was confirmed by FTIR and Raman spectroscopy experiments. The results showed a presence of C–O, C=N, graphite-like sp2, and mixed sp2-sp3 C–C bond vibrations. The surface topography was studied by atomic force microscopy. The rise in the beam power leads to a decrease in the surface roughness of the deposited DLC coatings. The studies on the corrosion resistance of the samples have been performed using three electrochemical techniques: open circuit potential (OCP), cyclic voltammetry (polarization measurements), and non-destructive electrochemical impedance spectroscopy (EIS). The measured corrosion potentials suggest that these samples are corrosion-resistant even in a medium, containing corrosive agents such as chloride ions. It can be concluded that the most corrosion-resistant specimen is DLC coating deposited on electron-beam-treated 304-L SS substrate by a beam power of 1500 W. Full article
(This article belongs to the Special Issue Advanced Coatings for Biomedical Applications)
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Review

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24 pages, 3488 KiB  
Review
Strategies to Enhance Biomedical Device Performance and Safety: A Comprehensive Review
by Julia Sánchez-Bodón, Maria Diaz-Galbarriatu, Leyre Pérez-Álvarez, Isabel Moreno-Benítez and José Luis Vilas-Vilela
Coatings 2023, 13(12), 1981; https://0-doi-org.brum.beds.ac.uk/10.3390/coatings13121981 - 21 Nov 2023
Cited by 2 | Viewed by 1314
Abstract
This paper reviews different approaches to obtain biomaterials with tailored functionalities and explains their significant characteristics that influence their bioactivity. The main goal of this discussion underscores the significance of surface properties in materials, with a particular emphasis on their role in facilitating [...] Read more.
This paper reviews different approaches to obtain biomaterials with tailored functionalities and explains their significant characteristics that influence their bioactivity. The main goal of this discussion underscores the significance of surface properties in materials, with a particular emphasis on their role in facilitating cell adhesion in order to obtain good biocompatibility and biointegration, while preventing adverse effects, such as bacterial contamination and inflammation processes. Consequently, it is essential to design strategies and interventions that avoid bacterial infections, reducing inflammation and enhancing compatibility systems. Within this review, we elucidate the most prevalent techniques employed for surface modification, notably emphasizing surface chemical composition and coatings. In the case of surface chemical composition, we delve into four commonly applied approaches: hydrolysis, aminolysis, oxidation, and plasma treatment. On the other hand, coatings can be categorized based on their material composition, encompassing ceramic-based and polymer-based coatings. Both types of coatings have demonstrated efficacy in preventing bacterial contamination, promoting cell adhesion and improving biological properties of the surface. Furthermore, the addition of biological agents such as drugs, proteins, peptides, metallic ions plays a pivotal role in manifesting the prevention of bacterial infection, inflammatory responses, and coagulation mechanism. Full article
(This article belongs to the Special Issue Advanced Coatings for Biomedical Applications)
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21 pages, 5309 KiB  
Review
Revisiting Tetra-p-Sulphonated Porphyrin as Antimicrobial Photodynamic Therapy Agent
by Rodica-Mariana Ion
Coatings 2021, 11(4), 393; https://0-doi-org.brum.beds.ac.uk/10.3390/coatings11040393 - 30 Mar 2021
Cited by 2 | Viewed by 2561
Abstract
Photodynamic inactivation is known as a new antimicrobial photodynamic therapy (aPDT). It is based on the administration of a photosensitizer located in the bacterial/viral cell followed by exposure to light radiations (with a proper wavelength corresponding with the maximum value of absorption of [...] Read more.
Photodynamic inactivation is known as a new antimicrobial photodynamic therapy (aPDT). It is based on the administration of a photosensitizer located in the bacterial/viral cell followed by exposure to light radiations (with a proper wavelength corresponding with the maximum value of absorption of the photosensitizer) that generate singlet oxygen or reactive oxygen species, which lead to the death of different microorganisms. This review will present an overview beyond the state-of-the-art of the photosensitizer types (based on tetra-p-sulphonated-phenyl porphyrin—TSPP, which is able to form cationic and J-aggregates forms at different pH values ((1–4) and concentrations around 10−5 M) and their applications of PDT for viruses, especially. The mechanism of dicationic and J-aggregates formation is presented in this paper, and the photophysical parameters have been collected and harmonized to support their behaviours. Studies on Herpes Simplex virus type 1 (HSV-1) are useful, because without the help of HSV-1, the COVID-19 virus may not be able to cause serious illness or death in humans. This method could be a new direction for COVID treatment and immunization, either to prevent infections or to develop photoactive fabrics (e.g., masks, suits, gloves) to disinfect surfaces, under artificial light and/or natural sunlight. The use of photodynamic therapy (PDT) can be an alternative approach against SARS-CoV-2 that deserves to be explored. Full article
(This article belongs to the Special Issue Advanced Coatings for Biomedical Applications)
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