Tissue Engineering Approaches for Regenerative Dentistry

A special issue of Dentistry Journal (ISSN 2304-6767). This special issue belongs to the section "Restorative Dentistry and Traumatology".

Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 3371

Special Issue Editor


E-Mail Website
Guest Editor
Department of Periodontics and Endodontics, School of Dental Medicine, University at Buffalo, Buffalo, NY 14214, USA
Interests: biomaterials; dental pulp regeneration; inflammation; root canal disinfection

Special Issue Information

Dear Colleagues,

Regenerative approaches in dentistry provide a potential treatment for oral disease and reconstruction of the tissues that are otherwise lost or cannot be replaced by biological tissues. Tissue regeneration requires the triad of tissue engineering (growth factors, scaffold, and stem cells) to induce tissue healing in the sterile environment, while it also requires bacterial and inflammatory control during the treatment of infectious disease in the oral cavity. Although regenerative treatment approaches have good clinical outcomes in most case reports, outcomes are still unpredictable. For this reason, innovative and novel biomaterials, anti-microbial, and anti-inflammatory protocols are required to improve tissue regeneration for dental applications.

We would like to invite you to submit your research regarding potential and novel biomaterials and treatment protocols for dental tissue regeneration in the oral cavity to contribute to this unique and compelling area where tissue regeneration needs to be achieved in a balance with inflammatory and microbial control. Please refer to the following keywords below to submit to this Special Issue.

Sincerely,

Dr. Hacer Aksel
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Dentistry Journal is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Bone tissue regeneration
  • Craniofacial reconstruction
  • Hard and soft tissue regeneration in oral cavity
  • Inflammation
  • Periodontal ligament tissue regeneration
  • Pulp and dentin tissue regeneration
  • Microbial control
  • Tissue engineering
  • Biomaterials
  • Hydrogels
  • Growth factors
  • Stem cells

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

11 pages, 8233 KiB  
Article
Contact Angle and Cell Adhesion of Micro/Nano-Structured Poly(lactic-co-glycolic acid) Membranes for Dental Regenerative Therapy
by Naoyuki Kaga, Hiroki Fujimoto, Sho Morita, Yuichiro Yamaguchi and Takashi Matsuura
Dent. J. 2021, 9(11), 124; https://0-doi-org.brum.beds.ac.uk/10.3390/dj9110124 - 20 Oct 2021
Cited by 5 | Viewed by 2541
Abstract
Biodegradable membranes are used in regenerative dentistry for guided tissue regeneration (GTR) and guided bone regeneration (GBR). In this study, patterned poly(lactic-co-glycolic acid) (PLGA) membranes with groove, pillar, and hole structures were successfully fabricated by thermal nanoimprinting. Their surfaces were evaluated [...] Read more.
Biodegradable membranes are used in regenerative dentistry for guided tissue regeneration (GTR) and guided bone regeneration (GBR). In this study, patterned poly(lactic-co-glycolic acid) (PLGA) membranes with groove, pillar, and hole structures were successfully fabricated by thermal nanoimprinting. Their surfaces were evaluated for topography by scanning electron microscopy and laser microscopy, for hydrophobicity/hydrophilicity by contact angle analysis, and for MC3T3-E1 cell adhesion. The sizes of the patterns on the surfaces of the membranes were 0.5, 1.0, and 2.0 μm, respectively, with the height/depth being 1.0 μm. The pillared and holed PLGA membranes were significantly more hydrophobic than the non-patterned PLGA membranes (p < 0.05). However, the 0.5 μm- and 1.0 μm-grooved PLGA membranes were significantly more hydrophilic than the non-patterned PLGA membranes (p < 0.05). The 0.5 μm-grooved, pillared, and holed membranes exhibited significantly superior adhesion to the MC3T3-E1 cells than the non-patterned PLGA (p < 0.05). These results suggest that patterned PLGA membranes can be clinically used for GTR and GBR in the dental regeneration field. Full article
(This article belongs to the Special Issue Tissue Engineering Approaches for Regenerative Dentistry)
Show Figures

Figure 1

Back to TopTop