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Diagnostics
Special Issues
Diagnosis of Spinal Tumors: 3rd Edition
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Diagnosis of Spinal Tumors: 3rd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 July 2024 | Viewed by 304

Special Issue Editor

Dr. Andrea Angelini

E-Mail Website
Guest Editor
Department of Orthopedics and Orthopedic, University of Padova, Padova, Italy
Interests: musculoskeletal oncology; orthopedic oncology; orthopedics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Primary and metastatic tumors of the spine are demanding lesions in terms of their diagnosis and management because they are often asymptomatic or have non-specific characteristics. Their delayed diagnosis is not very unusual, and sometimes, spinal instability or neurological compromise may be the presenting symptom. The optimal diagnosis and treatment of spine tumors require a multidisciplinary approach and thorough knowledge of both spinal surgery and musculoskeletal oncology. This Special Issue highlights the relevance of spinal tumors, particularly their diagnostic parameters and innovative diagnostic approaches.

Dr. Andrea Angelini
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • spinal column
  • sarcoma
  • metastasis
  • spinal neoplasms
  • palliative surgery
  • neurologic symptoms
  • spinal instability
  • benign tumors
  • imaging

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Published Papers (1 paper)

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13 pages, 16159 KiB  
Case Report
Electrochemotherapy in Spine Metastases: A Case Series Focused on Technical Aspects, Surgical Strategies and Results
by Andrea Angelini, Alberto D’Amico, Stefania Paolilli, Riccardo Signori, Giovanni Baldin, Giuseppe Di Rubbo, Luca Denaro and Pietro Ruggieri
Diagnostics 2024, 14(9), 936; https://0-doi-org.brum.beds.ac.uk/10.3390/diagnostics14090936 - 30 Apr 2024
Viewed by 200
Abstract
Metastases are complications of primary tumors due to prolonged cancer survival and have become an important issue for oncological patients and the most frequent cause of death and disability. Bone metastases occur at a later stage of cancer disease, and the spine is [...] Read more.
Metastases are complications of primary tumors due to prolonged cancer survival and have become an important issue for oncological patients and the most frequent cause of death and disability. Bone metastases occur at a later stage of cancer disease, and the spine is the most frequent site. To date, the aim of the treatment of metastases remains to be the control of disease and provide a satisfactory quality of life. The decision making of treatment is influenced by several factors such as the status of the primary disease, the number of metastases, site involvement, and the performance status of the patients. For this reason, the treatment of metastases is challenging and undergoes constant development. Therefore, alternative techniques with respect to surgery, which is the first option but not always practicable, and radiochemotherapy are attractive. Lately, electrochemotherapy has emerged as an innovative method for treating various primary and metastatic solid tumors, showing promising outcomes in terms of inducing tumor tissue necrosis and alleviating symptoms. This technique uses electric pulses to increase the uptake of chemotherapy by tumor cells. Despite the initial enthusiasm and good results in the treatment of bone tumors, relatively few papers have described its use in spine metastases. Therefore, we conducted a systemic review of this intriguing topic while also reporting our experience in the use of electrochemotherapy for the treatment of spine metastases. Full article
(This article belongs to the Special Issue Diagnosis of Spinal Tumors: 3rd Edition)
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