Rodent Genetic Models for Human Diseases

Dear Colleagues,

Animal experiments are essential to the understanding of different disease mechanisms, the discovery of new treatments, the diverse function of genes and the impact of epi-mutation and their mechaniscm.

Among the numerous animal models, rodents are especially preferred due to their size, ability to breed and the wealth of knowledge on their anatomy physiology and genetic makeup. The recent advances in gene editing technologies, such as CRISPR/Cas9, have propelled the importance of rodent genetic models even further.

We are pleased to invite you to submit a manuscript for our upcoming Special Issue on "Rodent Genetic Models for Human Diseases" in the Genes Journal, Section Molecular Genetics and Genomics. This Special Issue aims to provide a comprehensive overview of the latest research on the use of rodent genetic models in the study of human diseases.

Your expertise in this field would make a valuable contribution to the Special Issue, and we would be honoured to have you as a contributor. We encourage you to submit a manuscript that showcases your latest research and insights in this area.

We welcome original research articles, reviews, and perspectives that address the following topics:

• The development and characterization of new rodent genetic models for human diseases
• The application of rodent genetic models to study disease mechanisms and identify new therapeutic targets
• The use of rodent genetic models to test potential therapies for human diseases
• The role of gene editing technologies, such as CRISPR/Cas9, in the development of more precise and efficient rodent genetic models
• The ethical considerations surrounding the use of animals in biomedical research

Manuscripts should be prepared according to the Genes author guidelines, and all submissions will undergo a rigorous peer-review process. The deadline for manuscript submission is 30th of April 2024.

If you have any questions or require further information, please do not hesitate to contact us. We look forward to hearing from you and receiving your manuscript.

Sincerely,

Dr. Marie-Christine Birling
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• transgenic animal models
• rodent
• mouse
• rat
• genetic engineering
• CRISPR/Cas9
• model validation
• targeted transgenesis
• humanized models
• knock-out models