Submit to JCM Review for JCM Propose a Special Issue

Journal Browser

Ethnic Differences in Dermatitis and Atopic Eczema and Its Management

Print Special Issue Flyer
Special Issue Editors
Special Issue Information
Keywords
Published Papers

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dermatology".

Deadline for manuscript submissions: closed (25 March 2023) | Viewed by 10405

Share This Special Issue

Special Issue Editors

Prof. Dr. Gil Yosipovitch

E-Mail Website
Guest Editor

Dr Phillip Frost Department of Dermatology and Cutaneous Surgery and Miami Itch Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA
Interests: chronic itch; atopic eczema; psoriasis; complex medical dermatology

Prof. Dr. Giampiero Girolomoni

E-Mail Website
Guest Editor

Division of Dermatology and Venereology, Department of Medicine, University of Verona, Piazzale A. Stefani 1, I-37126 Verona, Italy
Interests: psoriasis; psoriatic arthritis; atopic dermatitis; immunopharmacology; skin biology; skin immune system; skin and internal diseases
Special Issues, Collections and Topics in MDPI journals

Dr. Valeria Aoki

E-Mail Website
Guest Editor

Laboratory of Dermatology and Immunodeficiencies, LIM-56, Department of Dermatology, Tropical Medicine Institute of São Paulo, University of São Paulo Medical School, São Paulo, Brazil
Interests: autoimmune blistering diseases (fogo selvagem, pemphigus, bullous pemphigoid, epidermolysis bullosa acquisita); inflammatory dermatoses (atopic dermatitis and lichen planus)

Dr. Takashi Hashimoto

E-Mail Website
Guest Editor

Department of Dermatology, National Defense Medical College, Tokorozawa, Japan
Interests: inflammation; clinical dermatology; allergic diseases; itch

Special Issue Information

Dear Colleagues,

Atopic eczema and dermatitis affect diverse ethnic groups with substantial ethnic disparities in the prevalence, treatment, progression and outcomes of AD conditions. Elucidating the mechanisms underlying these group differences is of crucial importance in reducing and eliminating disparities in treatment of atopic eczema. In recent years accumulating evidence has identified a variety of immune factors and genetic polymorphism that influence the susceptibility to AD and response to treatment. We now understand that in Black and Asian individuals AD is more frequent and could be more severe. Few studies have been conducted in Hispanic skin. Unfortunately, most of the studies are conducted in individuals of European ancestry.

In this special edition we review differences in epidemiology, clinical phenotype and treatment of AD in multiple ethnic groups and races. We highlight the mechanisms behind these differences including cellular, molecular, immunological, physiological therapeutic and explaining the disparities in AD. We look forward to your submissions!

Prof. Dr. Gil Yosipovitch
Prof. Dr. Giampiero Girolomoni
Dr. Valeria Aoki
Dr. Takashi Hashimoto
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

atopic eczema
dermatitis
allergy
itch
skin disease
treatment
prevention
epidemiology
ethnic differences
cellular
molecular
immunological
physiological therapeutic

Published Papers (6 papers)

Download All Papers

Research

Jump to: Review

9 pages, 223 KiB

Open AccessArticle

Impact of a Digital Atopic Dermatitis Educational Intervention on Hispanic Patients and Family Members

by Luis Fernando Andrade, MaryJo Bekhash, Siri Choragudi, Juan M. Gonzalez, Rodrigo Valdes and Gil Yosipovitch

J. Clin. Med. 2023, 12(6), 2130; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm12062130 - 08 Mar 2023

Viewed by 1337

Abstract

With the increasing incidence of atopic dermatitis (AD) in the U.S., the highest prevalence of AD being found in Hispanic countries, and the rising Hispanic-American population, educational resources on eczema focused on Spanish-speaking populations are needed more than ever. As such, the primary goal of this project was to assess the beneficial impact of an educational intervention conducted through a virtual platform for Hispanic individuals living with atopic dermatitis. Utilizing WhatsApp, the study enrolled 55 participants diagnosed with AD and/or parents of children diagnosed with AD. Participants were enrolled in a seven-day educational module with daily topics on AD health knowledge. A health knowledge survey was administered before the educational program, upon completion of the program, and one month after completion. The program found a 14% increase in AD health knowledge upon completion of the program (p < 0.001). Most importantly, there was no significant difference found between the health knowledge survey submitted at program completion and one month after completion, signaling that health knowledge taught through the course was successfully retained by participants (p = 0.29). Qualitative themes involving atopic disease were additionally explored through group discussions, including mental health and peer stigma. This study is the first of its kind in dermatology utilizing the WhatsApp format. The success of retained health knowledge regarding AD demonstrates that future virtual endeavors can be effective and accessible methods of patient education overall for populations that might not have ease of access to major medical centers. Full article

(This article belongs to the Special Issue Ethnic Differences in Dermatitis and Atopic Eczema and Its Management)

Review

Jump to: Research

12 pages, 628 KiB

Open AccessReview

Burden of Disease; the Current Status of the Diagnosis and Management of Atopic Dermatitis in China

by Chaoying Gu, Xu Yao and Wei Li

J. Clin. Med. 2023, 12(16), 5370; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm12165370 - 18 Aug 2023

Cited by 3 | Viewed by 2452

Abstract

Atopic dermatitis (AD) is now a global health problem and has been attracting extensive attention from both academic and public society in China. This review aimed to present the current status of the prevalence, disease burden, clinical features, diagnosis, and management of AD in China. The prevalence of AD has been increasing rapidly in China during the past decades, partially due to the increased recognition of the disease; there are still substantial amounts of over-diagnosed eczema and under-diagnosed AD. Chinese dermatologists see many AD patients with atypical manifestation, which poses a challenge to the diagnosis. The Chinese diagnostic criteria for adults and pediatric patients with AD have been proposed respectively and validated with high sensitivity and specificity. International and Chinese guidelines for management of AD have been popularized; however, there are still many practices that need verification through randomized case-control study. Dupilumab and JAK inhibitors have demonstrated favorable efficacy for AD patients in China, and a multidimensional approach is needed for selection of the patients and evaluation of the efficacy and safety. Patient education and long-term management for AD are just beginning in China, and need to be strengthened in the future. Full article

(This article belongs to the Special Issue Ethnic Differences in Dermatitis and Atopic Eczema and Its Management)

► Show Figures

Figure 1

13 pages, 290 KiB

Open AccessReview

Burden of Disease and Unmet Needs in the Diagnosis and Management of Atopic Dermatitis in Diverse Skin Types in Australia

by Ashling Courtney, Diego J. Lopez, Adrian J. Lowe, Zack Holmes and John C. Su

J. Clin. Med. 2023, 12(11), 3812; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm12113812 - 01 Jun 2023

Cited by 2 | Viewed by 1582

Abstract

Atopic dermatitis (AD) is a common, chronic, inflammatory skin disease affecting Australians of all ages, races, ethnicities, and social classes. Significant physical, psychosocial, and financial burdens to both individuals and Australian communities have been demonstrated. This narrative review highlights knowledge gaps for AD in Australian skin of colour. We searched PubMed, Wiley Online Library, and Cochrane Library databases for review articles, systematic reviews, and cross-sectional and observational studies relating to AD in Australia for skin of colour and for different ethnicities. Statistical data from the Australian Institute of Health and Welfare and the Australian Bureau of Statistics was collected. In recent years, there has been substantially increased awareness of and research into skin infections, such as scabies and impetigo, among various Australian subpopulations. Many such infections disproportionately affect First Nations Peoples. However, data for AD itself in these groups are limited. There is also little written regarding AD in recent, racially diverse immigrants with skin of colour. Areas for future research include AD epidemiology and AD phenotypes for First Nations Peoples and AD trajectories for non-Caucasian immigrants. We also note the evident disparity in both the level of understanding and the management standards of AD between urban and remote communities in Australia. This discrepancy relates to a relative lack of healthcare resources in marginalised communities. First Nations Peoples in particular experience socioeconomic disadvantage, have worse health outcomes, and experience healthcare inequality in Australia. Barriers to effective AD management must be identified and responsibly addressed for socioeconomically disadvantaged and remote-living communities to achieve healthcare equity. Full article

(This article belongs to the Special Issue Ethnic Differences in Dermatitis and Atopic Eczema and Its Management)

7 pages, 223 KiB

Open AccessReview

Ethnicity, Race and Skin Color: Challenges and Opportunities for Atopic Dermatitis Clinical Trials

by Robert Bissonnette, Jasmina Jankicevic, Etienne Saint-Cyr Proulx and Catherine Maari

J. Clin. Med. 2023, 12(11), 3805; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm12113805 - 01 Jun 2023

Viewed by 1507

Abstract

The number of clinical trials conducted in patients with atopic dermatitis is increasing steadily. These trials are conducted in several countries across all continents and include patients of different ethnicity, race and skin color. This diversity is desired, but it also brings challenges, including the diagnosis and evaluation of disease severity in patients with different skin colors; the influence of ethnicity on the perception of quality of life and patient reported outcomes; the inclusion of ethnicities that are only present in one country or that live far from clinical research sites; and the reporting of drug safety information. There is a need to better train physicians on the evaluation of atopic dermatitis in patients with different skin colors and a need to improve the systematic reporting of ethnicity, race and skin color in clinical trial publications. Full article

(This article belongs to the Special Issue Ethnic Differences in Dermatitis and Atopic Eczema and Its Management)

13 pages, 290 KiB

Open AccessReview

Burden of Disease and Unmet Needs in the Diagnosis and Management of Atopic Dermatitis in Korea

by Yu Ri Woo and Hei Sung Kim

J. Clin. Med. 2023, 12(11), 3744; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm12113744 - 29 May 2023

Cited by 1 | Viewed by 1293

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin condition associated with a significant disease burden in Korea. AD is highly prevalent among Korean children, adolescents, and adults, and can cause physical discomfort, psychological distress, and social isolation for those affected. Despite advances in our understanding of AD, there are still many unmet needs in diagnosing and managing the disease in Korea. One of the challenges in diagnosing AD is the lack of a definitive biomarker for AD in Korea, and there is a need for more effective, safe, and cost-effective treatments for AD. Therefore, finding out the current epidemiology, burden of AD, and how AD is currently being diagnosed in Korea and reviewing management options available in Korea will help resolve the unmet needs of AD patients in Korea. Addressing these and other unmet needs in AD management and diagnosis in Korea may improve outcomes for those affected by this challenging condition. Full article

(This article belongs to the Special Issue Ethnic Differences in Dermatitis and Atopic Eczema and Its Management)

11 pages, 403 KiB

Open AccessReview

Are There Ethnic Differences in Hand Eczema? A Review

by Eleanor Shu Xian Chai, Hong Liang Tey and Ziying Vanessa Lim

J. Clin. Med. 2023, 12(6), 2232; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm12062232 - 14 Mar 2023

Viewed by 1368

Abstract

Hand eczema is a common disease with economic and social ramifications. This study undertakes a review of certain existing literature to provide insight into contributory factors which may result in the varying prevalence and severity of hand eczema among different ethnic groups, particularly to identify modifiable risk factors, as well as to ascertain knowledge gaps for future research direction. The existing literature suggests that factors including (a) genes, (b) differing skin physiology, (c) cultural practices, (d) dietary habits and associated food preparation, (e) climate, (f) predominant occupations, (g) socioeconomic factors, and (h) dissimilar laws and regulations may account for the disparity in the risk of hand eczema among different ethnicities. Given that endogenous factors cannot be avoided, but certain exogenous aspects can be modified, especially as the environment plays an important role in hand eczema flares, it is helpful from a practical perspective to focus on addressing the modifiable risk factors. These factors pertain to unique cultural practices, customs, and food preparation methods. Healthcare professionals should be well-acquainted with such factors to tailor the treatment approach for patients of different ethnicities accordingly because, with globalization, physicians face increasingly diverse patient populations such that cultural customs no longer remain limited to particular geographic regions. Full article

(This article belongs to the Special Issue Ethnic Differences in Dermatitis and Atopic Eczema and Its Management)

► Show Figures