Dear colleagues,

Several groundbreaking innovations, made possible by technological progress, entered the field of cardiac pacing in recent years. However, their benefits have yet to fully emerge.

In addition to guideline-directed medical therapy, cardiac resynchronization therapy (CRT) is the cornerstone treatment for selected patients with heart failure (HF). About 30% of patients receiving CRT do not derive a detectable clinical or echocardiographic benefit, highlighting that there is room to improve candidates’ selection, CRT delivery, and device programming. Conduction system pacing has recently emerged as an alternative. However, data on cardiac remodeling and hard outcomes are still scant, especially in the long term. Remote monitoring of cardiac implantable electronic devices (CIEDs) is recommended as part of the individualized multidisciplinary follow-up of HF patients. Although useful in the early detection of CIEDs technical issues, cardiac arrhythmias, and impending HF decompensation, there is still uncertainty regarding its effectiveness in reducing mortality and hospitalizations.

With this Special Issue, we would like to explore the impact of leading-edge cardiac pacing technologies on patient outcomes including but not restricted to mortality, hospitalizations, quality of life, cardiac remodeling, device- or procedure-related complications, heart failure management, and arrhythmias diagnosis. In this regard, we encourage researchers to submit their work on the following key aspects of cardiac pacing: cardiac resynchronization therapy, conduction system pacing, leadless pacing, and ablate and pace strategies.

With this Special Issue, we would like to explore the impact of leading-edge cardiac pacing technologies on patient outcomes including but not restricted to mortality, hospitalizations, quality of life, cardiac remodeling, device- or procedure-related complications, heart failure management, and arrhythmias diagnosis. In this regard, we encourage researchers to submit their work on the following key aspects of cardiac pacing: cardiac resynchronization therapy, conduction system pacing, leadless pacing, and ablate and pace strategies.

Dr. Jacopo Francesco Imberti
Prof. Dr. Giuseppe Boriani
Guest Editors

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• atrial fibrillation
• arrhythmias
• channellopathies
• coronary artery disease
• heart failure
• cardiomyopathies
• acute coronary syndrome
• device therapy