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Clinical Research in Neurosurgery
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Clinical Research in Neurosurgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 676

Special Issue Editor

Prof. Dr. Yasuo Murai

E-Mail Website
Guest Editor
Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan
Interests: cerebral aneurysm; moyamoya disease; meningioma; RNF 213; exoscope; intracerebral hemorrhage
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In neurosurgery, surgical treatment employing a microscope has been the mainstay of therapy, but the roles of endovascular treatment, endoscopy, exoscope, and stereotactic radiation therapy are certainly expanding. However, from a global perspective, microscope surgery still holds a crucial position. Despite advancements in various surgical equipment, it is vital to remember that it is the surgeons who perform the surgeries, and the transmission of individual surgeons' education and technical nuances is indispensable.

In this project, we aim to examine the nuances of techniques in order to enhance surgical outcomes, education in those techniques, key points in the application of the latest surgical equipment, postoperative management considerations in the development of various novel drugs, as well as long-term prognosis and effectiveness. It is unclear whether the true treatment outcomes desired by patients can be adequately presented based solely on the short-term results of novel treatments. We look forward to receiving contributions from neurosurgeons, neurologists, and neuroradiologists regarding the latest diagnosis and treatment strategies and diagnostic equipment, and their clinically relevant and realistic effects.

Prof. Dr. Yasuo Murai
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cerebral aneurysm
  • microsurgery
  • surgical instrument
  • exoscope
  • surgical technique
  • moyamoya disease
  • endoscope
  • postoperative management
  • long-term results
  • vascular reconstructive surgery
  • brain tumor
  • cerebral hemorrhage

Published Papers (1 paper)

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Research

11 pages, 1616 KiB  
Article
Pathological Findings of Donor Vessels in Bypass Surgery
by Yohei Nounaka, Yasuo Murai, Asami Kubota, Atsushi Tsukiyama, Fumihiro Matano, Kenta Koketsu and Akio Morita
J. Clin. Med. 2024, 13(7), 2125; https://0-doi-org.brum.beds.ac.uk/10.3390/jcm13072125 - 06 Apr 2024
Viewed by 491
Abstract
(1) Background Cerebral revascularization is necessary to treat intracranial arterial stenosis caused by moyamoya disease, atherosclerosis, or large complex aneurysms. Although various donor vascular harvesting methods have been reported safe, there are no reports on the histological evaluation of donor vessels for each [...] Read more.
(1) Background Cerebral revascularization is necessary to treat intracranial arterial stenosis caused by moyamoya disease, atherosclerosis, or large complex aneurysms. Although various donor vascular harvesting methods have been reported safe, there are no reports on the histological evaluation of donor vessels for each disease, despite the variety of diseases wherein vascular anastomosis is required. (2) Methods Pathological findings of the superficial temporal artery (STA), radial artery (RA), occipital artery (OA), and saphenous vein (SV) harvested at the institution were analyzed. Patients classified according to aneurysm, atherosclerosis, and moyamoya disease were assessed for pathological abnormalities, medical history, age, sex, smoking, and postoperative anastomosis patency. (3) Results There were 38 cases of atherosclerosis, 15 cases of moyamoya disease, and 30 cases of aneurysm in 98 donor vessels (mean age 57.2) taken after 2006. Of the 84 STA, 11 RA, 2 OA, and 1 SV arteries that were harvested, 71.4% had atherosclerosis, 11.2% had dissection, and 10.2% had inflammation. There was no significant difference in the proportion of pathological findings according to the disease. A history of hypertension is associated with atherosclerosis in donor vessels. (4) Conclusions This is the first study to histologically evaluate the pathological findings of donor vessels according to disease. The proportion of dissection findings indicative of vascular damage due to surgical manipulation was not statistically different between the different conditions. Full article
(This article belongs to the Special Issue Clinical Research in Neurosurgery)
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