Biocompatible Bioceramics: Synthesis, Characterization and Medical Applications

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Bone Biomaterials".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 1717

Special Issue Editors


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Guest Editor
Institute for Research and Development, Universidade do Vale do Paraiba, Sao Jose dos Campos, São Paulo, Brazil
Interests: bioglass; calcium aluminate cement; porous scaffolds; ceramic–polymer biocomposites; electrospinning; bone regeneration; functional bioceramics

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Guest Editor
Hospital Israelita Albert Einstein, Universidade do Vale do Paraíba, São Paulo, Brazil
Interests: calcium aluminate cement; porous scaffolds; ceramic–polymer biocomposites; electrospinning; bone regeneration; advanced ceramics for biomedical devices

Special Issue Information

Dear Colleagues,

Bioceramic materials have the potential to meet biomedical requirements in terms of mechanical strength, biological functionality, and biocompatibility. The growing demand for biocompatible materials, increasing aging population, and increasing use to replace diseased hard tissues in the body are among the key factors that have driven the growth of the bioceramic materials market.The valuation of the global bioceramics market is set to reach USD 24.92 billion in 2030, which is expected to further appreciate at 10.10% CAGR (Compound Annual Growth Rate) during the assessment period (2021–2030).These materials have been used for a wide range of functions, including as dense materials for direct implants and reconstructive materials (plates, etc.) and as porous materials to help native bone cells grow naturally. Tissue engineering, stem cell technology, nanotechnology, electrospinning, and 3D bioprinting play key roles in different bioceramic and composite materials.

This Special Issue aims to bring together works on the latest advances in bioceramic materials in terms of synthesis, characterization, and biomedical applications, whether pure or combined with other bioceramics and/or biopolymers, such as in the development of artificial bones and teeth, pulp-capping materials, skin for grafting, joint replacements, load-bearing parts, coating materials, drug delivery platforms, membranes, and biomimetic scaffolds.

Prof. Dr. Ivone Regina de Oliveira
Prof. Dr. Fernando dos Santos Ortega
Guest Editors

Manuscript Submission Information

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Keywords

  • bioceramic
  • nanocomposite
  • bone regeneration
  • tissue engineering
  • 3D bioprinting
  • porous scaffolds
  • electrospinning
  • nanotechnology
  • drug delivery
  • surface treatment

Published Papers (1 paper)

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Research

14 pages, 2717 KiB  
Article
Biphasic Bioceramic Obtained from Byproducts of Sugar Beet Processing for Use in Bioactive Coatings and Bone Fillings
by Miguel Suffo-Pino, Miguel Ángel Cauqui-López, Celia Pérez-Muñoz, Daniel Goma-Jiménez, Natalia Fernández-Delgado and Miriam Herrera-Collado
J. Funct. Biomater. 2023, 14(10), 499; https://0-doi-org.brum.beds.ac.uk/10.3390/jfb14100499 - 09 Oct 2023
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Abstract
This study focuses on developing hydroxyapatite synthesized from a CaCO3-rich byproduct of sugar beet processing called Carbocal® using a hydrothermal reactor. The purpose of this biomaterial is to enhance the osteoinductivity of implantable surfaces and serve as a bone filler, [...] Read more.
This study focuses on developing hydroxyapatite synthesized from a CaCO3-rich byproduct of sugar beet processing called Carbocal® using a hydrothermal reactor. The purpose of this biomaterial is to enhance the osteoinductivity of implantable surfaces and serve as a bone filler, providing a sustainable and economically more affordable alternative. This research involved compositional analysis and micro- and macrostructural physicochemical characterization, complemented with bioactivity and live/dead assays. The biphasic nature of the Carbocal®-derived sample was significant within the context of the bioactivity concept previously proposed in the literature. The bioactivity of the biomaterial was demonstrated through a viability test, where the cell growth was nearly equivalent to that of the positive control. For comparison purposes, the same tests were conducted with two additional samples: hydroxyapatite obtained from CaCO3 and commercial hydroxyapatite. The resulting product of this process is biocompatible and possesses properties similar to natural hydroxyapatite. Consequently, this biomaterial shows potential as a scaffold in tissue engineering and as an adhesive filler to promote bone regeneration within the context of the circular bioeconomy in the geographical area proposed. Full article
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