Marine Natural Products with Antifouling Activity, 3rd Edition

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Synthesis and Medicinal Chemistry of Marine Natural Products".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 1799

Special Issue Editors


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CIIMAR | Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Novo Edifício do Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, s/n 4450-208 Matosinhos, Portugal
Interests: marine biology and ecology; marine environmental health; marine biotechnology; sustainable antifouling strategies; natural bioactive metabolites; bioproducts and biomaterials
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Guest Editor
1. Laboratório de Química Orgânica e Farmacêutica, Departamento de Ciências, Químicas, Faculdade de Farmácia, Universidade do Porto, Rua Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal
2. CIIMAR | Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Novo Edifício do Terminal de Cruzeiros do Porto de Leixões, Avenida General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal
Interests: medicinal chemistry; synthesis of sulfated and glycosylated small-molecule mimetics of heparin; discovery of biological activities for persulfated versus partially sulfated small molecules; antifouling studies of partially sulfated small molecules; antithrombotic studies of persulfated small molecules; structure–activity and structure–property relationship studies of bioactive small molecules
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Marine biofouling is one of the natural phenomena representing a challenge worldwide due to the costly effects on shipping and maritime-related industries and the related environmental threats. Intense research is aimed at new methods for preventing, controlling, or reducing fouling development in different submerged marine structures. The most prevalent solution to inhibit fouling is to make surfaces unsuitable for settlers, using coatings with repellent AF properties. Most of the AF agents in use in these coatings have undesirable effects on nontarget species, including commercially important ones. The search for new nontoxic antifouling technologies has become a necessity, particularly after the ban on organotin compounds such as tributyltin (TBT), one of the most efficient and widespread antifouling agents. Alternative organic and metal-based biocides are now used in antifouling paints, but their persistence and toxic effects in the aquatic environment have been reported. A nontoxic alternative for antifouling protection comes from the possibility of adopting natural antifouling compounds that may be found in sessile marine invertebrates like sponges, bryozoans, corals, and tunicates, as well as in marine microorganisms. Such metabolites prevent their producers from being fouled on by other organisms, or are simply products of their secondary metabolism and may act as bioactive compounds for several purposes. As natural marine compounds, they may inhibit settlements through a nontoxic mechanism without posing adverse effects on the marine environment. Such compounds can constitute new harmless ingredients for antifouling coatings. So far, a rather limited number of natural product antifoulants (NPAs) have been isolated from marine organisms, but a huge reservoir of compounds with potential antifouling activity is hidden in marine organisms. This Special Issue on Marine Natural Products with Antifouling Activity, 3rd Edition aims to discover such natural compounds, the use of these compounds as an inspiration for the design of new ones, their activity against biofouling species settlement, the evaluation of environmental fate parameters, and their application in antifouling coatings as novel environmentally friendly agents. Studies which may contribute to the advancement of  knowledge in the antifouling scientific field are also welcome.

Dr. Joana Reis Almeida
Dr. Marta Correia-da-Silva
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • marine natural compounds
  • antifouling
  • toxicity
  • coatings
  • environment

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Published Papers (1 paper)

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Review

13 pages, 299 KiB  
Review
Bioactive Peptides from Barnacles and Their Potential for Antifouling Development
by Xuan Liu, Hui Jin, Gaochi Xu, Ren Lai and Aili Wang
Mar. Drugs 2023, 21(9), 480; https://0-doi-org.brum.beds.ac.uk/10.3390/md21090480 - 30 Aug 2023
Viewed by 1484
Abstract
Barnacles, a prevalent fouler organism in intertidal zones, has long been a source of annoyance due to significant economic losses and ecological impacts. Numerous antifouling approaches have been explored, including extensive research on antifouling chemicals. However, the excessive utilization of small-molecule chemicals appears [...] Read more.
Barnacles, a prevalent fouler organism in intertidal zones, has long been a source of annoyance due to significant economic losses and ecological impacts. Numerous antifouling approaches have been explored, including extensive research on antifouling chemicals. However, the excessive utilization of small-molecule chemicals appears to give rise to novel environmental concerns. Therefore, it is imperative to develop new strategies. Barnacles exhibit appropriate responses to environmental challenges with complex physiological processes and unique sensory systems. Given the assumed crucial role of bioactive peptides, an increasing number of peptides with diverse activities are being discovered in barnacles. Fouling-related processes have been identified as potential targets for antifouling strategies. In this paper, we present a comprehensive review of peptides derived from barnacles, aiming to underscore their significant potential in the quest for innovative solutions in biofouling prevention and drug discovery. Full article
(This article belongs to the Special Issue Marine Natural Products with Antifouling Activity, 3rd Edition)
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