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Advances in Bacterial Cellulose Composites

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 12914

Special Issue Editors


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Guest Editor
Department of Physical and Colloidal Chemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Str., 020950 Bucharest, Romania
Interests: quality by design (QbD); analytical quality by design (AQbD); drug systems formulation (chitosan); surfaces’ characteristics (wettability/hydrophilicity/hydrophobicity—pharmaceutical powders)
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Physical and Colloidal Chemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Str., 020950 Bucharest, Romania
Interests: biomaterials (collagen drug delivery systems); rheology; cosmeceuticals; drug systems formulation and technological processes optimization; response surface methodology; Taguchi design
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Physical and Colloidal Chemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Str., 020950 Bucharest, Romania
Interests: targeted drug delivery; nanoparticulate systems; solubility enhancement techniques; biotechnology; topical/transdermal drug delivery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Over the last few decades, bacterial cellulose (BC) has been established as one of the most studied and modified bioplymers. Today, BC composites, having impressive features, are mostly designed and synthesized for targeted applications. Therefore, specific characteristics such as biocompatible, antimicrobial, magnetic, conducting, or mechanical special characteristics of BC composites can be expected, opening important fields of cutting-edge applications, from artificial organs to optoelectronic or display devices using BC and BC composites as substrate materials.

The Special Issue is indended to provide eye-catching themes for the most important applications of bacterial cellulose composites that continually extend the frontiers of new and challenging biomaterials.

The main focus of the Special Issue, “Advances in Bacterial Cellulose Composites”, is to present an update on the newest strategies for synthesis of BC and BC composites, to exceedingly boost their applications: From the development of biomedical devices, attachment of biological molecules, and combinations with pharmaceutical materials; to optoelectronics, conducting devices, displays, sensors or bio-sensors, and other advanced materials.

The topics of interest for this Special Issue include but are not limited to the key words listed below:

  • Bacterial cellulose (BC), bacterial cellulose composites;
  • Reinforcement materials for synthesizing multifunctional BC composites;
  • Applications in the medical field, medical devices, artificial organs (skin, scaffold, blood vessels, heart valves, liver, cornea, bone, cartilage), tissue engineering, regenerative medicine;
  • Applications in electronic/conducting fields (display devices, LEDs, conducting nanomaterials, electroconductive films, optically transparent films, magnetically responsive films, sensors and biosensors, flexible displays).

We invite you to submit original research articles, review articles, commentaries, and editorials discussing the use of bacterial cellulose (BC) and BC composites, in the most varied fields.

All submissions are welcome.

Prof. Dr. Lacramioara Popa
Prof. Dr. Mihaela Violeta Ghica
Prof. Dr. Cristina Elena Dinu-Pirvu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Bacterial cellulose (BC), bacterial cellulose composites
  • Reinforcement materials for synthesizing multifunctional BC composites
  • Applications in the medical field, medical devices, artificial organs (skin, scaffold, blood vessels, heart valves, liver, cornea, bone, cartilage), tissue engineering, regenerative medicine
  • Applications in electronic/conducting fields (display devices, LEDs, conducting nanomaterials, electroconductive films, optically transparent films, magnetically responsive films, sensors and biosensors, flexible displays).

Published Papers (3 papers)

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Research

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15 pages, 1860 KiB  
Article
Bacterial Nanocellulose Fortified with Antimicrobial and Anti-Inflammatory Natural Products from Chelidonium majus Plant Cell Cultures
by Sylwia Zielińska, Adam Matkowski, Karolina Dydak, Monika Ewa Czerwińska, Magdalena Dziągwa-Becker, Mariusz Kucharski, Magdalena Wójciak, Ireneusz Sowa, Stanisława Plińska, Karol Fijałkowski, Daria Ciecholewska-Juśko, Michał Broda, Damian Gorczyca and Adam Junka
Materials 2022, 15(1), 16; https://0-doi-org.brum.beds.ac.uk/10.3390/ma15010016 - 21 Dec 2021
Cited by 5 | Viewed by 3694
Abstract
In this work we developed a bi-functional Bacterial-Nano-Cellulose (BNC) carrier system for cell cultures of Chelidonium majus—a medicinal plant producing antimicrobial compounds. The porous BNC was biosynthesized for 3, 5 or 7 days by the non-pathogenic Komagataeibacter xylinus bacteria and used in [...] Read more.
In this work we developed a bi-functional Bacterial-Nano-Cellulose (BNC) carrier system for cell cultures of Chelidonium majus—a medicinal plant producing antimicrobial compounds. The porous BNC was biosynthesized for 3, 5 or 7 days by the non-pathogenic Komagataeibacter xylinus bacteria and used in three forms: (1) Without removal of K. xylinus cells, (2) partially cleaned up from the remaining K. xylinus cells using water washing and (3) fully purified with NaOH leaving no bacterial cells remains. The suspended C. majus cells were inoculated on the BNC pieces in liquid medium and the functionalized BNC was harvested and subjected to scanning electron microscopy observation and analyzed for the content of C. majus metabolites as well as to antimicrobial assays and tested for potential proinflammatory irritating activity in human neutrophils. The highest content and the most complex composition of pharmacologically active substances was found in 3-day-old, unpurified BNC, which was tested for its bioactivity. The assays based on the IL-1β, IL-8 and TNF-α secretion in an in vitro model showed an anti-inflammatory effect of this particular biomatrix. Moreover, 3-day-old-BNC displayed antimicrobial and antibiofilm activity against Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans. The results of the research indicated a possible application of such modified composites, against microbial pathogens, especially in local surface infections, where plant metabolite-enriched BNC may be used as the occlusive dressing. Full article
(This article belongs to the Special Issue Advances in Bacterial Cellulose Composites)
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Review

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28 pages, 1500 KiB  
Review
Bacterial Cellulose—A Remarkable Polymer as a Source for Biomaterials Tailoring
by Lăcrămioara Popa, Mihaela Violeta Ghica, Elena-Emilia Tudoroiu, Diana-Georgiana Ionescu and Cristina-Elena Dinu-Pîrvu
Materials 2022, 15(3), 1054; https://0-doi-org.brum.beds.ac.uk/10.3390/ma15031054 - 29 Jan 2022
Cited by 45 | Viewed by 4907
Abstract
Nowadays, the development of new eco-friendly and biocompatible materials using ‘green’ technologies represents a significant challenge for the biomedical and pharmaceutical fields to reduce the destructive actions of scientific research on the human body and the environment. Thus, bacterial cellulose (BC) has a [...] Read more.
Nowadays, the development of new eco-friendly and biocompatible materials using ‘green’ technologies represents a significant challenge for the biomedical and pharmaceutical fields to reduce the destructive actions of scientific research on the human body and the environment. Thus, bacterial cellulose (BC) has a central place among these novel tailored biomaterials. BC is a non-pathogenic bacteria-produced polysaccharide with a 3D nanofibrous structure, chemically identical to plant cellulose, but exhibiting greater purity and crystallinity. Bacterial cellulose possesses excellent physicochemical and mechanical properties, adequate capacity to absorb a large quantity of water, non-toxicity, chemical inertness, biocompatibility, biodegradability, proper capacity to form films and to stabilize emulsions, high porosity, and a large surface area. Due to its suitable characteristics, this ecological material can combine with multiple polymers and diverse bioactive agents to develop new materials and composites. Bacterial cellulose alone, and with its mixtures, exhibits numerous applications, including in the food and electronic industries and in the biotechnological and biomedical areas (such as in wound dressing, tissue engineering, dental implants, drug delivery systems, and cell culture). This review presents an overview of the main properties and uses of bacterial cellulose and the latest promising future applications, such as in biological diagnosis, biosensors, personalized regenerative medicine, and nerve and ocular tissue engineering. Full article
(This article belongs to the Special Issue Advances in Bacterial Cellulose Composites)
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14 pages, 2248 KiB  
Review
An Overview Regarding Microbial Aspects of Production and Applications of Bacterial Cellulose
by Raluca Elisabeta Lupașcu, Mihaela Violeta Ghica, Cristina-Elena Dinu-Pîrvu, Lăcrămioara Popa, Bruno Ștefan Velescu and Andreea Letiția Arsene
Materials 2022, 15(2), 676; https://0-doi-org.brum.beds.ac.uk/10.3390/ma15020676 - 17 Jan 2022
Cited by 25 | Viewed by 3458
Abstract
Cellulose is the most widely used biopolymer, accounting for about 1.5 trillion tons of annual production on Earth. Bacterial cellulose (BC) is a form produced by different species of bacteria, representing a purified form of cellulose. The structure of bacterial cellulose consists of [...] Read more.
Cellulose is the most widely used biopolymer, accounting for about 1.5 trillion tons of annual production on Earth. Bacterial cellulose (BC) is a form produced by different species of bacteria, representing a purified form of cellulose. The structure of bacterial cellulose consists of glucose monomers that give it excellent properties for different medical applications (unique nanostructure, high water holding capacity, high degree of polymerization, high mechanical strength, and high crystallinity). These properties differ depending on the cellulose-producing bacteria. The most discussed topic is related to the use of bacterial cellulose as a versatile biopolymer for wound dressing applications. The aim of this review is to present the microbial aspects of BC production and potential applications in development of value-added products, especially for biomedical applications. Full article
(This article belongs to the Special Issue Advances in Bacterial Cellulose Composites)
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