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Evaluation of Novel Biomaterials in Endodontics, Periodontics, and Restorative Dentistry
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Evaluation of Novel Biomaterials in Endodontics, Periodontics, and Restorative Dentistry

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 8122

Special Issue Editor

Dr. Luciano Giardino

E-Mail Website
Guest Editor
Independent Researcher, 88900 Crotone, Italy
Interests: endodontic diseases; endodontic irrigants; histopathology; implant preservation; oral biofilm; periodontal regeneration; root canal shaping and cleaning; root canal anatomy; endoperiodontal-lesions
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The Special Issue, “Evaluation of Novel Biomaterials in Restorative Dentistry and Periodontics”, aims to bring together articles covering relevant scientific topics on endodontics and periodontics disease, pathogenesis, and advances in therapy. Moreover, the opportunity will be taken to discuss the state-of-the-art research on materials that could be used in restorative dentistry, endodontics, and periodontics. This Special Issue will consider the foundation of technical progress in endodontics and dentistry; the development of novel diagnostic and therapeutic possibilities; and the production of novel materials, technologies, and systems.

This Special Issue will be a timely approach to survey the recent progress in the development and optimization of these subjects. The articles presented in this Special Issue will cover various topics, ranging from advances in endodontics and periodontics diagnosis, pathogenesis, therapy, endodontic treatment, direct and indirect dental restoration, regenerative endodontics, regenerative/reparative periodontal approaches, and studies on oral microbiota. Therefore, this Special Issue welcomes contributions from all researchers working in dentistry, biomolecular sciences, or materials processing in relation to endo- and perio-dontal health and dental restoration.

Dr. Luciano Giardino
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial agents
  • bone graft
  • dental materials
  • endoperiodontal lesions
  • implant preservation
  • periodontal regeneration
  • regenerative endodontics
  • tooth preservation

Published Papers (3 papers)

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Research

12 pages, 2749 KiB  
Article
Autologous Dentin Graft after Impacted Mandibular Third Molar Extraction to Prevent Periodontal Pocket Formation—A Split-Mouth Pilot Study
by Giulia Mazzucchi, Marco Lollobrigida, Luca Lamazza, Giorgio Serafini, Dario Di Nardo, Luca Testarelli and Alberto De Biase
Materials 2022, 15(4), 1431; https://0-doi-org.brum.beds.ac.uk/10.3390/ma15041431 - 15 Feb 2022
Cited by 7 | Viewed by 2345
Abstract
This preliminary study aims to evaluate the efficacy of an autologous dentin graft in preventing periodontal defects after impacted or semi-impacted lower third molars’ (M3) surgical extraction. For this purpose, radiographic and periodontal evaluation of post-extractive sockets were performed. Ten patients were enrolled [...] Read more.
This preliminary study aims to evaluate the efficacy of an autologous dentin graft in preventing periodontal defects after impacted or semi-impacted lower third molars’ (M3) surgical extraction. For this purpose, radiographic and periodontal evaluation of post-extractive sockets were performed. Ten patients were enrolled in the study: twenty M3 extraction sockets were treated with a split-mouth modality. After tooth extraction, the experimental sites were filled with autologous dentin graft obtained by the extracted M3, while the control sites were filled with blood clot alone. Flaps were closed by first intention to ensure the stability of the wounds. Post-extractive sites were monitored at days 15, 90 and 180. The healing was not affected by any complications associated with the use of the autologous dentine graft in all cases. The measurements recorded at six months showed a reduction of the probing pocket depth distal to the second lower molar (M2) at both surgical sites, with a greater reduction observed at the experimental sites. Radiographic evaluation also showed a greater amount of bone gain at the grafted sites compared to the control sites. The results of this preliminary study suggest that autologous dentin grafts can be useful in preventing the formation of periodontal defects distal to M2 after M3 surgical extraction. Full article
(This article belongs to the Special Issue Evaluation of Novel Biomaterials in Endodontics, Periodontics, and Restorative Dentistry)
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9 pages, 503 KiB  
Article
Comparative Evaluation of the Penetration Depth into Dentinal Tubules of Three Endodontic Irrigants
by Luciano Giardino, Eugenio Pedullà, Francesco Cavani, Francesca Bisciotti, Luca Giannetti, Vittorio Checchi, Daniele Angerame, Ugo Consolo and Luigi Generali
Materials 2021, 14(19), 5853; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14195853 - 06 Oct 2021
Cited by 8 | Viewed by 2776
Abstract
This study aimed to examine the penetration depth into dentinal tubules of some chelating agents. The 17% EDTA and two preparations containing surfactants (Smear Clear, Bioakt Endo) were tested. Surface tension and liquid viscosity were measured using a Dynamic Contact Angle Analyzer and [...] Read more.
This study aimed to examine the penetration depth into dentinal tubules of some chelating agents. The 17% EDTA and two preparations containing surfactants (Smear Clear, Bioakt Endo) were tested. Surface tension and liquid viscosity were measured using a Dynamic Contact Angle Analyzer and a Haake rotational rheometer. To measure the penetration depth inside dentinal tubules, thirty maxillary central incisors were selected from a pool of extracted human permanent teeth and allocated to three experimental groups (10 samples each), as well as were mechanically shaped and cleansed with 5.25% NaOCl, followed by each of the chelators being labeled with 0.1 wt % Rhodamine B according to final irrigation protocol established. The samples were embedded in an epoxy resin, after which 200 μm thick transverse sections were obtained at 2, 5, and 8 mm from the apex with a saw microtome. The specimens were then observed using a confocal laser microscope (CLSM) and the penetration of the labeled solution was measured in every third of each sample. Statistical analysis was performed using ANOVA or Kruskal–Wallis tests according to the distribution of data, evaluated with the Shapiro–Wilk normality test. Viscosity and surface tension tests have shown that BioAKT Endo has the lowest values compared to EDTA and Smear Clear. The medium penetration depth did not significantly differ among the three irrigants, while it increased considerably from the apical to the coronal level in all groups. Additionally, the maximum penetration depth increased significantly from the apical to coronal level, while among groups, BioAKT Endo showed the highest values at the apical and middle level compared to the other irrigants. No significant differences were observed among the three groups in medium and maximum penetration depths when the entire root was considered. New irrigants containing surfactants show reduced surface tension and, in one case (BioAKT Endo), viscosity. The lowering of the surface tension allows for better penetration of liquids into dentinal tubules than EDTA alone, thus improving the cleaning of the root canal system. Full article
(This article belongs to the Special Issue Evaluation of Novel Biomaterials in Endodontics, Periodontics, and Restorative Dentistry)
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9 pages, 2379 KiB  
Article
Effects of Ultrasonic Activation on Root Canal Filling Quality of Single-Cone Obturation with Calcium Silicate-Based Sealer
by Sin-Young Kim, Young-Eun Jang, Bom Sahn Kim, Eun-Kyoung Pang, Kiche Shim, Hye Ryeon Jin, Min Kyung Son and Yemi Kim
Materials 2021, 14(5), 1292; https://0-doi-org.brum.beds.ac.uk/10.3390/ma14051292 - 08 Mar 2021
Cited by 6 | Viewed by 2229
Abstract
Background: We evaluated the effects of ultrasonic activation on root canal filling quality of the single-cone (SC) obturation technique with calcium silicate sealers and gutta percha cones. Methods: Thirty-six human single-rooted premolars were obturated with gutta percha and sealer. For the continuous wave [...] Read more.
Background: We evaluated the effects of ultrasonic activation on root canal filling quality of the single-cone (SC) obturation technique with calcium silicate sealers and gutta percha cones. Methods: Thirty-six human single-rooted premolars were obturated with gutta percha and sealer. For the continuous wave (CW) group (n = 12), AH Plus with a continuous wave technique was used. The SC group (n = 12) received EndoSequence BC sealer with a single-cone technique. The SCU (SC with the addition of ultrasonic activation) group (n = 12) received the same treatment. Micro-computed tomography was used to scan the teeth, and the void volume within the root canal was evaluated at the apical, middle, and coronal levels. Then cross-sections were observed under a light microscope and scanning electron microscope (SEM). Results: Void volume was significantly lower in the SCU group than in the CW and SC groups. There were no statistically significant differences between the CW and SC groups. The SCU group had fewer voids than the CW and SC groups in the coronal and middle third areas. Specimens showed no apparent gaps or voids in any group. SEM images revealed both gap-free and gap-containing regions at different levels in all groups. Conclusions: Single-cone obturation with calcium silicate-based sealers might obtain enhanced filling quality when used with ultrasonic activation. Full article
(This article belongs to the Special Issue Evaluation of Novel Biomaterials in Endodontics, Periodontics, and Restorative Dentistry)
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