Metabolic Effects of Foregut Surgery in the Management of Obesity and Diabetes

Dear Colleagues,

Metabolomic research has highlighted that foregut surgery (bariatric surgery or gastric cancer surgery) is responsible for metabolic effects and immediately alters various metabolic pathways. Investigations for discovering biomarkers predicting the outcome of foregut surgery are in the preliminary stages. Extensive research should be performed to identify significant metabolites and as well as to develop models and validate their predictive performance prior to clinical application. Preoperative prediction of metabolic effects induced by foregut surgery will enable better selection of surgical candidates and improve pre- and postoperative management of patients. Understanding short- and long-term systemic adaptations to foregut surgery may provide insights into the mechanisms underlying weight loss and comorbidities improvement and can lead to the discovery of new drug targets for obesity or diabetes treatment.

Prof. Dr. Sungsoo Park
Dr. Yeongkeun Kwon
Guest Editors

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• bariatric surgery
• metabolic surgery
• gastric cancer surgery
• metabolomics
• biomarker
• obesity
• type 2 diabetes