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Special Issue "Interactions between Metal Complexes and Biomolecules"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Bioorganic Chemistry".

Deadline for manuscript submissions: 31 May 2022.

Special Issue Editors

Dr. Li-Jun Chen
E-Mail Website
Guest Editor
Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia
Interests: supramolecular chemistry; self-assembly; molecular recognition; ion transport; coordination chemistry; metal–organic structures; biomolecules recognition
Dr. Chang Lei
E-Mail Website
Guest Editor
Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072, Australia
Interests: developing novel nanomaterials for bioanalysis and tissue regeneration; and their transactions to affordable commercial products to be used in real cases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Metal complexes are important materials that have the potential for programmable structures to be engineered with integrated properties.

They have attracted significant research interest both due to their aesthetically attractive structures and their appealing properties. Interactions between metal complexes and biomolecules including lipids, oligopeptides, nucleic acids, proteins, etc. comprise an important research area related to metal complexes and are important in chemistry, biology, medicine, pharmacy, nutrition, metabolism, and environmental science. Metal–biomolecule interactions endow metal complexes with potential applications ranging from sensing and bio-imaging to catalysis, drug delivery, chemotherapeutics, photo-therapeutics, theranostics and more. Many of these applications have been explored with different types of metal complexes, including simple organometallic compounds and metal coordination assemblies, offering insights into the future potential of these compounds for the investigation and treatment of human diseases. 

In this Special Issue of Molecules devoted to "Interactions between Metal Complexes and Biomolecules", we warmly invite investigators to contribute original research articles or review articles that could stimulate continuing efforts to understand the metal–biomolecule interactions and develop new metal-complex-related systems that intact with biomolecules. Topics of interest for this Special Issue include, but are not limited to, the following:

  • The synthesis, characterisation, and applications of new metal complexes or assemblies that can target and probe a specific biomolecule or as potential biomolecular binding substrates;
  • Molecular mechanistic understanding of the interaction between biomolecules and metal complexes;
  • The incorporation of biomolecules into metal-related systems, as well as the development and application of biomolecule–metal hybrid structures.

Dr. Li-Jun Chen
Dr. Chang Lei
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • metal complexes
  • biomolecules
  • interaction
  • organometallic complexes
  • hybrid structures
  • self-assembly

Published Papers

This special issue is now open for submission.
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