Polyamine Drug Discovery
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 10603
Special Issue Editors
Interests: medicinal chemistry; drug discovery; synthesis and structure–activity relationships of biologically active compounds; multitarget agents; hybrid compounds; polyamine analogues; polyamine conjugates; anticancer agents; amino oxidase inhibitors; neuroprotective agents; antioxidant molecules
Interests: Design and synthesis of small molecules as probes for the investigation of biological processes or as drug candidates for neurodegenerative diseases and cancer
Special Issue Information
Dear Colleagues,
Naturally occurring polyamines as well as synthetic polyamines affect various biological pathways through either activation or inhibition of these pathways. This indicates that polyamine research has a great potential in drug discovery for the treatment of different diseases. Many notable findings in this field have been concerned with the identification of polyamine analogues as chemopreventive and antiproliferative agents, antiparasitic compounds, neuroprotectants, and neurotransmitter receptor agonists/antagonists.
This Special Issue “Polyamines in Drug Discovery” welcomes the submission of review and research articles related to the design, synthesis, and pharmacological characterization of new polyamine-based molecules that could underlie innovative approaches in drug development, for example, by targeting polyamine metabolism and transport or by acting as epigenetic modulators.
Prof. Dr. Anna Mìnarini
Prof. Dr. Michela Rosini
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- anticancer agents;
- synthetic polyamines;
- polyamine conjugates;
- polyamine transport system;
- polyamine oxidase modulators;
- antiparasitic compounds;
- chemoprevention;
- neuroprotectants;
- monoamine oxidase inhibitors;
- epigenetic targets.