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Molecules
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Analysis and Application of Biomarkers in Environmental and Human Biomonitoring
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Analysis and Application of Biomarkers in Environmental and Human Biomonitoring

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Cross-Field Chemistry".

Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 7786

Special Issue Editors

Prof. Dr. Venera Ferrito

E-Mail Website
Guest Editor
Department of Biological, Geological and Environmental Sciences, University of Catania, Catania, Italy
Interests: fish species; fish as bioindicator; biomarkers of environmental pollution; aquatic pollution; molecular species identification
Dr. Anna Maria Pappalardo

E-Mail Website
Guest Editor
Dipartimento di Scienze Biologiche, Geologiche e Ambientali, Sez. di Biologia Animale “M. La Greca”, Università di Catania, Via Androne 81, 95124 Catania, Italy
Interests: DNA; PCR; DNA sequencing; molecular evolution; DNA barcoding; molecular phylogenetics; population genetics; marine biology; teleosts; biomarker of environmental pollution; molecular marker; food traceability; molecular species identification; transposable elements; cell biology
Special Issues, Collections and Topics in MDPI journals
Dr. Erminia Conti

E-Mail Website
Guest Editor
Department of Biological, Geological and Environmental Sciences, University of Catania, Catania, Italy
Interests: biomarkers of environmental pollution; ecotoxicology; oxidative stress; spiders as bioindicators; global changes; extreme environments
Prof. Dr. Christian Mulder

E-Mail Website
Guest Editor
Università degli Studi di Catania, Catania, Italy
Interests: soil invertebrates; nematodes and plants as bioindicators; food chains; ecological networks; ecological stoichiometry; global changes

Special Issue Information

Dear Colleagues,

The negative close relationship between environmental pollution and human and wildlife health is increasingly and dramatically evident, and the role of pollution biomarkers as a tool for measurement of the biological response to exposure to chemical contaminants is well established. For human biomonitoring, the associations between biomarkers and cancer risk in epidemiological studies are actively investigated using biomarkers of pollution exposures, including the food-chain contamination by toxicants widespread in the environment. The environmental biomonitoring is also highlighting the presence of emerging environmental contaminants, such as a diverse group of PCP substances and industrial chemicals (e.g., organophosphate flame retardants (OPFRs), phthalate esters, perfluorinated compounds (PFCs), and industrial phenols), the exposure and the effect of which on biota are being studied. Therefore, the development of new biomarkers, defined by biomolecular, biochemical, enzymatic, and chemical approaches, and the combination of different pollution biomarkers for classic and new contaminants detection are pivotal for evaluation of their impact. In this context, the Special Issue solicits the submission of original research and review articles on the effects of pollutants at different levels of biological organization, using also different analytical methods (e.g., liquid chromatography (LC), gas chromatography (GC) and mass spectrometry (MS)) to measure biomarkers of exposure, of effect and susceptibility, for human and wildlife health risk assessment.  

Prof. Dr. Venera Ferrito
Dr. Anna Maria Pappalardo
Dr. Erminia Conti
Prof. Dr. Christian Mulde
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • environmental pollution
  • biomarkers of exposure
  • biomarkers of effect
  • biomarkers of susceptibility
  • human health
  • wildlife health
  • food contamination

Published Papers (2 papers)

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Research

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15 pages, 278 KiB  
Article
Fish-Based Baby Food Concern—From Species Authentication to Exposure Risk Assessment
by Anna Maria Pappalardo, Chiara Copat, Alessandra Raffa, Luana Rossitto, Alfina Grasso, Maria Fiore, Margherita Ferrante and Venera Ferrito
Molecules 2020, 25(17), 3961; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules25173961 - 31 Aug 2020
Cited by 11 | Viewed by 4290
Abstract
In this work, two different but complementary approaches were used to evaluate the reliability of fish-based baby foods as a source of safe nourishment for babies. More specifically, barcoding analysis based on the Cytochrome Oxidase I sequences was used for fish species authentication [...] Read more.
In this work, two different but complementary approaches were used to evaluate the reliability of fish-based baby foods as a source of safe nourishment for babies. More specifically, barcoding analysis based on the Cytochrome Oxidase I sequences was used for fish species authentication and an analysis of metal/metalloid levels was performed to estimate the exposure risk assessment derived from consumption of selected fish-based baby food in infants and toddlers. COI DNA barcoding revealed that in three samples the species detected did not match the common name of the species shown on the label. In particular, G. chalcogrammus and M. australis were found in place of M. merluccius and O. mykiss was found in place of S. salar. The analysis of exposure risk assessment indicated a low risk for developing chronic systemic and carcinogenic effects in infants and toddler, under an exposure scenario based on daily consumption of a single box of fish-based baby food. However, it is important to highlight that in order to provide a comprehensive risk assessment it would be important to supplement the levels of exposure resulting from the total diet. Overall, our results suggest that more attention should be paid by authorities to ensure the safety of food for infants and toddlers. Full article
(This article belongs to the Special Issue Analysis and Application of Biomarkers in Environmental and Human Biomonitoring)

Other

Jump to: Research

13 pages, 1241 KiB  
Systematic Review
ILs and MMPs Levels in Inflamed Human Dental Pulp: A Systematic Review
by Konstantina Kritikou, Maria Greabu, Marina Imre, Daniela Miricescu, Alexandra Ripszky Totan, Marian Burcea, Iulia-Ioana Stanescu-Spinu and Tudor Spinu
Molecules 2021, 26(14), 4129; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules26144129 - 07 Jul 2021
Cited by 8 | Viewed by 2895
Abstract
A wide range of mediators are released from the pulp tissue because of bacterial invasion which causes inflammation. Interleukins (ILs) and matrix metalloproteinases (MMPs) have a leading role in initiating and spreading of inflammation because of their synergic action. Biomarkers such as ILs [...] Read more.
A wide range of mediators are released from the pulp tissue because of bacterial invasion which causes inflammation. Interleukins (ILs) and matrix metalloproteinases (MMPs) have a leading role in initiating and spreading of inflammation because of their synergic action. Biomarkers such as ILs and MMPs can be identified via several methods, establishing the inflammatory response of the dental pulp. The aim of this systematic review is to evaluate the levels of ILs and/or MMPs in human dental pulp. PubMed, OVID, Cochrane, Scopus, Web of Science and Wiley online library databases were searched for original clinical studies. After applying inclusion and exclusion criteria, a quality assessment of studies was performed based on a modified Newcastle-Ottawa scale. In the review were included articles that evaluated the presence of ILs and/or MMPs in pulp tissue using enzyme-linked immunosorbent assay (ELISA) or western blot or multiplex assay. Six articles were included in the present synthesis. Although various diagnostic methods were used, statistically significant higher levels of ILs and/or MMPs were mostly found in the experimental groups compared to healthy pulp samples. The biomarkers studied can be a promising tool to evaluate pulp tissue health or even in pulpitis treatment. Full article
(This article belongs to the Special Issue Analysis and Application of Biomarkers in Environmental and Human Biomonitoring)
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