A Novel and Powerful Tool for Bioactive Substance Stabilization and Delivery: Nanocarriers, Nanomotors and Nanorobotics

A special issue of Nanomaterials (ISSN 2079-4991). This special issue belongs to the section "Biology and Medicines".

Deadline for manuscript submissions: closed (8 September 2023) | Viewed by 1680

Special Issue Editors


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Guest Editor
School of Chemical and Material Engineering, Jiangnan University, Wuxi, China
Interests: extraction and separation of bioactive substances
Special Issues, Collections and Topics in MDPI journals
School of Chemical and Material Engineering, Jiangnan University, Wuxi, China
Interests: nanoencapsulation of bioactive ingredients; smart nanocarriers
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Bioactive substances have become the hot topic in medicine and cosmetic research in the past decades. Due to the poor stability and solubility of many bioactive substances, however, their utilization remains challenging. In recent years, nanotechnologies such as nanocarriers (including nanoencapsulation, nanoemulsion, nanosolid lipids, liposomes, noisomes, etc.) and smart vehicles (including nanorobotics, nanomotors, etc.) have been developed in depth. The employment of these novel technologies could greatly enhance the stability or the delivery capability of the bioactive ingredients, which is vital for the utilization of bioactive substances. However, these technologies are generally high-cost and have low universality; thus, we are calling for more efforts to be devoted to this field in the future.

This Special Issue plans to present a cross-section of the current research regarding nanotechnology for bioactive substance utilization, welcoming articles in the format of full papers, communications, and reviews. Potential topics include, but are not limited to:

  • Nanoencapsulation systems for bioactive substances;
  • Stabilization of bioactive substances using nanotechnology;
  • Novel fabrication and preparation methods for nanocarriers;
  • The structural characterization of liposomes and noisomes;
  • Nanomotors and nanorobotics for bioactive substance delivery;
  • Utilization of smart vehicles for medicine delivery;
  • Utilization of nanocarriers in cosmetic formulas.

Prof. Dr. Jing Wang
Dr. Kuan Chang
Guest Editors

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Keywords

  • bioactive substances
  • delivery system
  • medicine delivery
  • nanocarrier
  • nanoencapsulation
  • nanomotor
  • nanorobotics
  • nanovehicles
  • liposomes
  • noisomes

Published Papers (1 paper)

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Review

19 pages, 1167 KiB  
Review
Encapsulated Peptides and Proteins with an Effect on Satiety
by Rafael O. de A. Costa, Thaís S. Passos, Eloyse Mikaelly de S. Silva, Nicolle Caroline S. dos Santos and Ana Heloneida de A. Morais
Nanomaterials 2023, 13(7), 1166; https://0-doi-org.brum.beds.ac.uk/10.3390/nano13071166 - 24 Mar 2023
Viewed by 1368
Abstract
The world scenario has undergone a nutritional transition in which some countries have left the reality of malnutrition and now face an epidemic of excess body weight. Researchers have been looking for strategies to reverse this situation. Peptides and proteins stand out as [...] Read more.
The world scenario has undergone a nutritional transition in which some countries have left the reality of malnutrition and now face an epidemic of excess body weight. Researchers have been looking for strategies to reverse this situation. Peptides and proteins stand out as promising molecules with anti-obesity action. However, oral administration and passage through the gastrointestinal tract face numerous physiological barriers that impair their bioactive function. Encapsulation aims to protect the active substance and modify the action, one possibility of potentiating anti-obesity activity. Research with encapsulated peptides and proteins has demonstrated improved stability, delivery, controlled release, and increased bioactivity. However, it is necessary to explore how proteins and peptides affect weight loss and satiety, can impact the nutritional status of obesity, and how encapsulation can enhance the bioactive effects of these molecules. This integrative review aimed to discuss how the encapsulation of protein molecules impacts the nutritional status of obesity. From the studies selected following pre-established criteria, it was possible to infer that the encapsulation of proteins and peptides can contribute to greater efficiency in reducing weight gain, changes in adipose tissue function, and lower hormone levels that modulate appetite and body weight in animals with obesity. Full article
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