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Nanomaterials
Special Issues
Nanomaterials in Miniaturized Separation and Sensing Devices, Apparatuses and Installations
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Nanomaterials in Miniaturized Separation and Sensing Devices, Apparatuses and Installations

A special issue of Nanomaterials (ISSN 2079-4991).

Deadline for manuscript submissions: closed (6 September 2023) | Viewed by 2813

Special Issue Editors

Prof. Dr. Gheorghe Nechifor

E-Mail Website
Guest Editor
Analytical Chemistry and Environmental Engineering Department, University Politehnica of Bucharest, 011061 Bucharest, Romania
Interests: membrane materials, membranes and membrane processes; membrane reactors; clean and cleaning technologies; selective separation and sensing
Special Issues, Collections and Topics in MDPI journals
Dr. Aurelia Cristina Nechifor

E-Mail Website
Guest Editor
Analytical Chemistry and Environmental Engineering Department, Polytechnic University of Bucharest, 011061 Bucharest, Romania
Interests: the footprint of kynurenine pathway in neurodegeneration: Janus-Faced role in Parkinson’s disorder and therapeutic implications

Special Issue Information

Dear Colleagues,

Nanomaterials and nanostructures have become indispensable in many application fields: medicine, environment, transportation, agriculture, miscellaneous industry, communications and administration. With this in mind, we are dedicating a Special Issue of Nanomaterials titled Nanomaterials in miniaturized separation and sensing devices, apparatuses and installations with the aim of contributing to the involvement of materials and nanostructures for the development and optimization of technologies, reducing the consumption of materials, energy, and personnel by improving the design of devices, appliances, and installations through miniaturizing components without reducing performance. This direction could represent a sure way to sustainable development.

Contributions can be related to the miniaturization of sensors for physical, chemical, and especially biological parameters, but portable measuring and analysis devices are also of interest. At the same time, studies on the reduction of the size (based on the use of nanomaterials and nanostructures) of some machines and installations in various technical and technological fields will be highly appreciated.

Prof. Dr. Gheorghe Nechifor
Dr. Aurelia Cristina Nechifor
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nanomaterials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microsensors
  • cell separation
  • drug delivery
  • chromatography
  • ferrofluid transport or separation
  • heat transfer
  • lab on chip
  • radioisotope detection or separation
  • enzyme immobilization
  • microreactors/biomicroreactors
  • catalytic devices
  • concentrators

Published Papers (2 papers)

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Research

8 pages, 999 KiB  
Article
Carbon Nanopowder-Based Stochastic Sensor for Ultrasensitive Assay of CA 15-3, CEA and HER2 in Whole Blood
by Raluca-Ioana Stefan-van Staden, Oana-Raluca Musat, Damaris-Cristina Gheorghe, Ruxandra-Maria Ilie-Mihai and Jacobus (Koos) Frederick van Staden
Nanomaterials 2022, 12(18), 3111; https://0-doi-org.brum.beds.ac.uk/10.3390/nano12183111 - 08 Sep 2022
Cited by 2 | Viewed by 1138
Abstract
Two microsensors obtained by the physical immobilization of 5,10,15,20-tetraphenyl-21H,23H-porphine (TPP) and 5,10,15,20-tetrakis (pentafluorophenyl chloride)-21H,23H-iron (III) porphyrin (Fe(TPFPP)Cl) in carbon nanopowder decorated with gold nanoparticles (AuNp) were designed, characterized, validated and used for the molecular recognition and simultaneous ultrasensitive determination of CEA, CA15-3 and [...] Read more.
Two microsensors obtained by the physical immobilization of 5,10,15,20-tetraphenyl-21H,23H-porphine (TPP) and 5,10,15,20-tetrakis (pentafluorophenyl chloride)-21H,23H-iron (III) porphyrin (Fe(TPFPP)Cl) in carbon nanopowder decorated with gold nanoparticles (AuNp) were designed, characterized, validated and used for the molecular recognition and simultaneous ultrasensitive determination of CEA, CA15-3 and HER2 in whole blood. High sensitivities were recorded for both microsensors. Low limits of quantification were recorded for all biomarkers: CEA (12.8 pg mL−1 by using Fe(TPFPP)Cl/AuNp, and 190 fg mL−1 by using TPP/AuNp), CA 15-3 (100 fU mL−1 for both microsensors) and HER2 (3.9 fg mL−1 by using Fe(TPFPP)Cl/AuNp, and 35 fg mL−1 by using TPP/AuNp). A very good correlation between the results obtained using the proposed microsensors and ELISA, certified by the Student t-test, proves that the screening test can be used for ultrasensitive assays of the three biomarkers in whole blood. Full article
(This article belongs to the Special Issue Nanomaterials in Miniaturized Separation and Sensing Devices, Apparatuses and Installations)
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9 pages, 1973 KiB  
Article
Stochastic Microsensors Based on Carbon Nanotubes for Molecular Recognition of the Isocitrate Dehydrogenases 1 and 2
by Raluca-Ioana Stefan-van Staden, Catalina Cioates Negut, Sorin Sebastian Gheorghe and Paula Sfirloaga
Nanomaterials 2022, 12(3), 460; https://0-doi-org.brum.beds.ac.uk/10.3390/nano12030460 - 28 Jan 2022
Cited by 2 | Viewed by 1892
Abstract
Two three-dimensional (3D) stochastic microsensors based on immobilization of protoporphyrin IX (PIX) in single-walled carbon nanotubes (SWCNT) and multi-walled carbon nanotubes (MWCNT) decorated with copper (Cu) and gold (Au) nanoparticles were designed and used for the molecular recognition of isocitrate dehydrogenase 1 (IDH1) [...] Read more.
Two three-dimensional (3D) stochastic microsensors based on immobilization of protoporphyrin IX (PIX) in single-walled carbon nanotubes (SWCNT) and multi-walled carbon nanotubes (MWCNT) decorated with copper (Cu) and gold (Au) nanoparticles were designed and used for the molecular recognition of isocitrate dehydrogenase 1 (IDH1) and isocitrate dehydrogenase 2 (IDH2) in biological samples (brain tumor tissues, whole blood). The linear concentration ranges obtained for the molecular recognition and quantification of IDH1 and IDH2 were: IDH1 (1 × 10−5–1 × 102 ng mL−1) and IDH2 (5 × 10−8 − 5 × 102 ng mL−1). The limits of quantification obtained using the proposed microsensors were: 10 fg mL–1 for IDH1 and 5 × 10−3 fg mL−1 for IDH2. The highest sensitivities were obtained for the microsensor based on MWCNT. High recoveries versus enzyme-linked immunosorbent assay (ELISA) standard method were recorded for the assays of IDH1 and IDH2, all values being higher than 99.00%, with relative standard deviations (RSD) lower than 0.10%. Full article
(This article belongs to the Special Issue Nanomaterials in Miniaturized Separation and Sensing Devices, Apparatuses and Installations)
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