Non-Coding RNA and Glioblastoma

Dear Colleagues,

Diverse species of non-coding RNAs (ncRNAs) have been implicated in mediating countless processes taking place within and between cells, both physiological and pathological. These include numerous human malignancies where ncRNAs have been shown to act in the capacity of both pro-oncogenes and tumor suppressors. The glioblastoma is a gloomy example of one of fortunately few tumors whose morbidity and survival rates have not been significantly improved in recent decades. Its location within the most vital of organs combined with infamous heterogeneity, as well as its high degree of therapy resistance, leads to therapeutic failure and all but certain mortality within a quite short period after initial diagnosis. The past 15 or so years brought about a vast amount of information regarding the role of ncRNAs in various aspects of glioblastoma. MicroRNAs, long, non-coding RNAs, and other ncRNAs have been proven to shape various phenotypes of glioblastoma cells as well as their interaction with the tumor microenvironment, and many knock-down/replacement strategies have been demonstrated as actual modifiers of therapeutic efficacy. This Special Issue on the role of ncRNAs in glioblastoma aims to provide an update on the progress in the unraveling of multiple ncRNA-mediated mechanisms focusing on the molecular intricacies as well as on their therapeutic utility.

Dr. Agnieszka M Bronisz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Non-Coding RNA is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• non-coding RNA
• microRNA
• long non-coding RNAs
• glioblastoma
• tumor heterogeneity
• tumor microenvironment