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Polymers
Special Issues
Polymer Composites and Bioactive Materials for Tissue Engineering
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Polymer Composites and Bioactive Materials for Tissue Engineering

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 5120

Special Issue Editors

Prof. Dr. Fedor Senatov

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Guest Editor
Director of Center for Biomedical Engineering, National University of Science and Technology "MISIS", Moscow, Russia
Interests: biomaterials; biopolymers; bioprinting; biomimetics; implants; hybrid materials; tissue engineering
Special Issues, Collections and Topics in MDPI journals
Dr. Rajan Choudhary

E-Mail Website1 Website2
Guest Editor
Rudolfs Cimdins Riga Biomaterials Innovations and Development Centre, Institute of General Chemical Engineering, Riga Technical University, 1 Kalku Street, Riga 1658, Latvia
Interests: bone regeneration; biomaterials; antibacterial studies; drug delivery; polymeric composites; Hydrogels, bioceramics: characterization; synthesis; biowaste utilization; bioactivity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Polymer Composites and Bioactive Materials for Tissue Engineering deals with the scientific advancements of biomaterials that interact with cells or tissues (In vitro /In Vivo). Scaffolds are often based on nontoxic, biocompatible materials, and in some cases biodegradable if required. Mechanical properties, biomedical properties, rate of resorption, bioactivity, microstructure, and porous biomimetic architecture are important characteristics of polymer scaffolds. Polymer scaffolds are widely used for the regeneration of damaged or missing tissues, in vitro biological studies, cultivation of cells etc. Bioactive materials have unique adaptive quality with the physiological enviornment and are designed to stimulate and promote the regeneration of damaged tissues. Polymers combined with ceramics or biomolecules acting as a composite not only enhances the bioactivity of the scaffolds but also improves their flexibility/mouldability. Therefore, bioactive composites based on polymers are of special interest. Development of new biopolymer scaffolds and bioactive materials is critical to the success of tissue engineering and medical applications, connected with cell cultivation.

This Special Issue is concerned with structure, properties, and applications of polymer composites, including bioresorbable, bioinert polymers and bioactive materials for tissue engineering applications. Topics may include structural features, microstructure, the relationship between structure and properties and biomedical characteristics, tailored–architected scaffolds, biomimetic structure, mechanical properties, and bioactivity. The issue may also address bioactive materials such as hydrogels, bioceramics, smart polymers, shape memory polymers, self-fitting implants, tissue/cell engineering devices, tissue reconstruction, and cell-biomaterial interactions. Bioactive materials prepared specifically and functionally engineered either in their physical form (powder, fiber), surface topology (porosity, roughness), dimensions (nano to macro scales) to physiological behavior (In vitro/In vivo studies). Contributions focus on fundamental results, mechanisms, and applications that will help to compile the current state-of-the-art and to highlight their range of application. Both original contributions and reviews are welcome.

Prof. Dr. Fedor S. Senatov
Dr. Rajan Choudhary
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • biopolymers
  • polymers for biomedical application
  • bioresorbable polymers
  • biomimetics
  • smart polymers
  • implants
  • scaffolds
  • tissue engineering
  • tissue regeneration
  • cell engineering
  • polymer biocomposites
  • methods for preparing polymeric composites
  • surface modification and their characterization
  • hydrogels

Published Papers (2 papers)

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Research

10 pages, 8383 KiB  
Communication
Osteoconductive Effect of a Nanocomposite Membrane Treated with UV Radiation
by Yusser Olguín, Soledad Acuna-Mendoza, Carolina Otero, Cristian A. Acevedo and Cristian Covarrubias
Polymers 2022, 14(2), 289; https://0-doi-org.brum.beds.ac.uk/10.3390/polym14020289 - 11 Jan 2022
Viewed by 1307
Abstract
Modulation of the bio-regenerative characteristics of materials is an indispensable requirement in tissue engineering. Particularly, in bone tissue engineering, the promotion of the osteoconductive phenomenon determines the elemental property of a material be used therapeutically. In addition to the chemical qualities of the [...] Read more.
Modulation of the bio-regenerative characteristics of materials is an indispensable requirement in tissue engineering. Particularly, in bone tissue engineering, the promotion of the osteoconductive phenomenon determines the elemental property of a material be used therapeutically. In addition to the chemical qualities of the constituent materials, the three-dimensional surface structure plays a fundamental role that various methods are expected to modulate in a number of ways, one most promising of which is the use of different types of radiation. In the present manuscript, we demonstrate in a calvarial defect model, that treatment with ultraviolet irradiation allows modification of the osteoconductive characteristics in a biomaterial formed by gelatin and chitosan, together with the inclusion of hydroxyapatite and titanium oxide nanoparticles. Full article
(This article belongs to the Special Issue Polymer Composites and Bioactive Materials for Tissue Engineering)
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12 pages, 3286 KiB  
Article
Polymer Composite Materials Based on Polylactide with a Shape Memory Effect for “Self-Fitting” Bone Implants
by P. A. Zhukova, F. S. Senatov, M. Yu. Zadorozhnyy, N. S. Chmelyuk and V. A. Zaharova
Polymers 2021, 13(14), 2367; https://0-doi-org.brum.beds.ac.uk/10.3390/polym13142367 - 19 Jul 2021
Cited by 11 | Viewed by 3779
Abstract
The development of adaptive medical structures is one of the promising areas of bioengineering. Polymer composite materials based on polylactide (PLA) are interesting not only for their properties, such as biocompatibility, mechanical properties, biodegradation, and convenience of use, but also for demonstrating shape [...] Read more.
The development of adaptive medical structures is one of the promising areas of bioengineering. Polymer composite materials based on polylactide (PLA) are interesting not only for their properties, such as biocompatibility, mechanical properties, biodegradation, and convenience of use, but also for demonstrating shape memory effect (SME). In this study, reducing the activation initiation temperature and the SME activation energy was achieved by forming a composite based on PLA containing 10% poly (ε-caprolactone) (PCL). The effect of the plasticizer on the structure, mechanical properties, and especially SME of the composite, was studied by DSC, SEM, FTIR spectroscopy, compression tests, and DMA. By varying the composition, the beginning of the SME activation was reached at 45 °C, and the apparent activation energy of the process decreased by 85 kJ/mol, ensuring safe and effective use of the material as a precursor for temporary self-fitting scaffolds for reconstructive surgery. Full article
(This article belongs to the Special Issue Polymer Composites and Bioactive Materials for Tissue Engineering)
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