Application of Advanced Synthetic Biological Approaches in Microbial Platforms
A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Biological Processes and Systems".
Deadline for manuscript submissions: closed (20 February 2024) | Viewed by 4637
Special Issue Editor
Interests: genome biology; synthetic biology; metabolic engineering; microbial platform engineering; bioproduction and bioprocess; prion science and engineering; gene therapy and biologics development; vaccine development
Special Issue Information
Dear Colleagues,
The presence of a robust microbial platform is recognized as one of the key factors in the efficient production of biochemicals and biologics. For many years, the development of microbiological platforms has focused on performing mutations and genetic engineering on hosts screened from natural resources. However, such attempts have been difficult, costly, and time-consuming and have required extensive knowledge. Recently, synthetic biology, which has continued to evolve remarkably in recent years, has greatly spurred the development of new biological systems. This approach is now at the stage of replacing traditional host development for highly efficient production.
The field of synthetic biology mainly includes (1) the synthesis of genes, genomes, and life; (2) the synthesis of new metabolic pathways; (3) modular engineering of proteins; and (4) the development of biosensors, the majority of which can be verified in modified cells. To achieve the various goals of synthetic biology in this approach, we need to know how to properly design and engineer chassis cells that meet the needs in the market. Toward this end, it is important to define the meaning of chassis cells clearly and determine the path how to design and produce microbial platform with novel metabolic function for industrial applications in the future.
This Special Issue focuses on the current progress in synthetic biology-aided pathway rewiring in microbial platform (chassis cells), also in microbial platform development that meet the needs in the industrial processes and discusses its impact on the production of biochemicals and biologics. Therefore, we enthusiastically invite papers related to these such issues. Also, we most welcome to the papers presenting novel inventions with the values of basic research applications for advanced synthetic biology-aided microbial platform development.
Prof. Dr. Prihardi Kahar
Guest Editor
Manuscript Submission Information
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