Special Issue "Scorpion Toxins"
Deadline for manuscript submissions: closed (31 March 2018).
Venoms from scorpions are known to possess a wide variety of potential components for the development of new drugs, as well as insecticides. These molecules appear to have evolved primarily for subjugating prey and for chemical defense, resulting in high degrees of potency and specificity particularly for key signaling molecules in the nervous system. Scorpion toxins, which specifically interfere with ionic channels functioning, have been characterized so far. In addition to these disulfide-bridged peptides, scorpion venoms contain a great diversity of non-disulfide-bridged peptides presenting antimicrobial, immunomodulatory, hypotensive, and antitumoral activities.
This Special Issue of Toxins will cover recent developments relating to scorpion toxins, including evolution, mechanism of action, structure-function, as well as, development or application of screening methods for scorpion toxins, and use and/or development of antivenoms against scorpion toxins.
The individual articles will review:
1. Proteomic analysis of scorpion venom
2. Transcriptomic analysis of venomous glands of scorpions
3. Peptides affecting Ion-channel function
4. Non-disulfide-bridged peptides peptides
5. Antivenoms against scorpion toxins
6. Immunomodulatory activity of scorpion venom toxins
7. Pharmacokinetics, and pharmacodynamics of scorpion toxins
Prof. Elisabeth Ferroni Schwartz
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a double-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxins is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- K+-channel blockers
- Na+-channel modulators
- Cl--channel toxins
- Ca2+-channel toxins
- Antimicrobial peptides
- Antitumoral peptides