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Brief Report

Genetic Diversity and Epidemiological Significance of Wild Boar HEV-3 Strains Circulating in Poland

1
Department of Food and Environmental Virology, National Veterinary Research Institute, Al. Partyzantów 57, 24-100 Puławy, Poland
2
Center of Translational Medicine, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska Street 100, 02-797 Warsaw, Poland
3
Department of Animal Science, Agricultural University of Athens, 75 Iera Odos, 11-855 Athens, Greece
*
Author to whom correspondence should be addressed.
Academic Editors: Ayato Takada, Magdalena Materniak-Kornas and Jacek Kuźmak
Received: 23 April 2021 / Revised: 24 May 2021 / Accepted: 15 June 2021 / Published: 19 June 2021
(This article belongs to the Special Issue State-of-the-Art Animal Virus Research in Poland)
The wild boar is the most important reservoir of zoonotic HEV-3 strains among different wildlife species. The aim of the study was subtype identification of wild boar HEV-3 strains circulating in Poland. Wild boar liver was used in the study in the form of homogenates prepared from 57 samples positive for HEV in a real-time RT-PCR. These samples were collected from juvenile and adult wild boars hunted in the jurisdictions of different Regional Directorates of State Forests (RDSF) across Poland. Subtype identification of detected HEV strains was based on a phylogenetic analysis of the most conserved HEV ORF2 genome fragment. Out of 57 tested samples, consensus HEV ORF2 sequences of 348 bp were obtained for 45 strains. Nineteen strains were identified and belonged to the HEV gt 3a and 3i subtypes, whereas 26 were not assigned to any virus subtype. HEV gt 3i strains prevailed in the Polish wild boar population, 16 of such were identified, and they were significantly more often observed in the RDSF Katowice area (χ2 = 28.6, p = 0.027 (<0.05)) compared to other regions of the country. Circulation of 3a strains was limited only to the RDSF Gdańsk territory (χ2 = 48, p = 0.000 (<0.05)). The virus strains detected in the Polish population of wild boars representing previously identified HEV subtypes in wild boars, pigs, or humans in Europe are of epidemiological importance for public health. View Full-Text
Keywords: wild boar; hepatitis E virus; strain subtyping; genetic diversity; epidemiological significance wild boar; hepatitis E virus; strain subtyping; genetic diversity; epidemiological significance
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MDPI and ACS Style

Kozyra, I.; Bigoraj, E.; Jabłoński, A.; Politi, K.; Rzeżutka, A. Genetic Diversity and Epidemiological Significance of Wild Boar HEV-3 Strains Circulating in Poland. Viruses 2021, 13, 1176. https://0-doi-org.brum.beds.ac.uk/10.3390/v13061176

AMA Style

Kozyra I, Bigoraj E, Jabłoński A, Politi K, Rzeżutka A. Genetic Diversity and Epidemiological Significance of Wild Boar HEV-3 Strains Circulating in Poland. Viruses. 2021; 13(6):1176. https://0-doi-org.brum.beds.ac.uk/10.3390/v13061176

Chicago/Turabian Style

Kozyra, Iwona, Ewelina Bigoraj, Artur Jabłoński, Katerina Politi, and Artur Rzeżutka. 2021. "Genetic Diversity and Epidemiological Significance of Wild Boar HEV-3 Strains Circulating in Poland" Viruses 13, no. 6: 1176. https://0-doi-org.brum.beds.ac.uk/10.3390/v13061176

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