Nutraceutical Components of Foods—Current State of the Art

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Food Science and Technology".

Deadline for manuscript submissions: closed (15 September 2021) | Viewed by 2539

Special Issue Editor


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Guest Editor
Faculty of Food Science, University of Warmia and Mazury in Olsztyn, Pl. Cieszyński 1, 10-719 Olsztyn-Kortowo, Poland
Interests: food proteins; bioinformatic analysis; bioactive and functional peptides; bioactive peptide sequences; cheminformatic approach
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Special Issue Information

Dear Colleagues,

We are all familiar with the popular slogan “you are what you eat”, and at present everyone is becoming more aware of the impact of the diet on their health. Moreover, the media promote a great deal of information on so-called healthy eating, diets, and lifestyle fashions. Distinguishing what is reliable or not is often difficult for the consumer. Additionally, the contemporary world struggles with the aging of the population, which requires the design of the diet for “healthy aging”. In this context, nutraceuticals, as health-supportive substances, do not lose their significance. They are still in the focus of the scientific interests and are continuously developing worldwide.

I am honored to announce this Special Issue entitled "Current State of the Art—Nutraceutical Components of Foods”. This Issue initiates a new MDPI journal called Nutraceuticals, and the articles published within it will be joined together under the same title with an Applied Sciences Special Issue. Our Special Issue is addressed to all scientists who study, among other things, i) the therapeutic potential of food-derived food compounds; ii) their analysis using in vitro, in vivo, and in silico methodologies; iii) the impact of dietary patterns on the risk of diet-related diseases; iv) the interactions between nutraceutical foods and other food components in the context of human health; v) the novel technologies aiming to provide a nutraceutical to the organism in an active form; and vi) the pros and cons of nutraceutical food. All types of articles (i.e., reviews, original papers, and short communications) are kindly welcome.

Benefits of publishing in the joint Special Issue of Nutraceuticals and Applied Sciences:

  • Open access (unlimited access);
  • Indexed by the Science Citation Index Expanded (Web of Science) [search for "Applied Sciences-Basel",2.474, 5-Year IF: 2.458], Scopus [CiteScore: 2.50], Inspec (IET) and other databases;
  • Rapid turn-around: approximately 2 weeks from submission to the first decision.

I look forward to hearing from you.

Best regards,

Prof. Dr. Anna Iwaniak
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

13 pages, 1105 KiB  
Communication
In Vitro Evaluation of Cytotoxicity and Proliferative Effects of Lyophilized Porcine Liver Tissue on HepG2 Hepatoma Cells and Adipose-Tissue-Derived Mesenchymal Stromal Cells
by Priscilla Berni, Virna Conti, Orlando Ferroni, Roberto Ramoni, Giuseppina Basini and Stefano Grolli
Appl. Sci. 2021, 11(15), 6691; https://0-doi-org.brum.beds.ac.uk/10.3390/app11156691 - 21 Jul 2021
Cited by 1 | Viewed by 1612
Abstract
In recent years, nutritional supplements from different sources have been widely considered to support medical treatments in patients affected by chronic hepatopathies. Their potential therapeutic benefit has been recognized, but some evidence of safety issues has been reported. Recently it has been hypothesized [...] Read more.
In recent years, nutritional supplements from different sources have been widely considered to support medical treatments in patients affected by chronic hepatopathies. Their potential therapeutic benefit has been recognized, but some evidence of safety issues has been reported. Recently it has been hypothesized that the liver could produce various of bioactive factors to maintain organ homeostasis and promote tissue healing. Thus, liver-specific preparations containing bioactive factors could provide a suitable substrate for in vitro study of liver tissue maintenance/healing, as a prospective regenerative medicine approach. Furthermore, they could represent a dietary supplement or nutraceutical for adjuvant therapies when correctly prepared and formulated. This work aims to provide data about the safety and biological activity of a freeze-dried porcine liver preparation. The lyophilized powder obtained from the whole organ has been tested in term of in vitro cell cytotoxicity (MTT assay) and proliferation assays (bromo-deoxyuridine incorporation and direct cell count) in two different cell types: human hepatoma HepG2 cell line and adipose-tissue-derived canine mesenchymal stromal cells (At-MSCs). At concentration levels between 100 to 500 µg/mL, the lyophilized liver powder stimulated mitochondrial metabolism as assessed by MTT assay (p ≤ 0.001 for HepG2 and for At-MSCs) and induced an increase in bromo-deoxyuridine incorporation in both cell types (p ≤ 0.01 for HepG2 and p < 0.001 for At-MSCs). In addition, direct cell count demonstrated a higher proliferative activity in treated At-MSCs (p < 0.001). Although preliminary, these data suggest that the whole-liver powder is noncytotoxic in vitro and may represent a stimulus to cell metabolism and proliferation. Further studies are needed to detect the bioactive components of the supplement and characterize in deeper detail the cellular pathways that they can modulate. Full article
(This article belongs to the Special Issue Nutraceutical Components of Foods—Current State of the Art)
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