Novel Technologies in Radiology and Radiobiology

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 11979

Special Issue Editor


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Guest Editor
1. Radiology and Physical Medicine Department, School of Medicine, University of Murcia, 30100 Murcia, Spain
2. Instituto Murciano de Investigación Biosanitaria “Virgen de la Arrixaca” (IMIB-Arrixaca), 30100 Murcia, Spain
Interests: ionizing radiation; radiation effects; radiobiology; radiation protection; radiology; radiotherapy; radioprotectors; radiosensitizers; nonionizing radiation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Ionizing radiation is widely used in industry, mining, agriculture, research, and medicine.

The objective of this special Issue of Applied Sciences on “Novel Technologies in Radiology and Radiobiology” is to cover the latest developments in applied science in the field of ionizing radiation.

Potential topics of interest for this Special Issue include (but are not limited to) the following areas:

- Detection and dosimetry of ionizing radiation;

- Implementation of advances in medical radiation technology and techniques, in industry and in research;

- Dose response models and low dose rates;

- Management of the natural environment, including the protection of biota;

- Industrial, research, processing, transport and decontamination applications;

- Management and waste disposal;

- Radón, terrestrial radiation and radionuclides, and cosmic radiation, including space;

- Effects of ionizing radiation, including biological mechanisms, health risk assessment, and exposure characteristics;

- Ecological consequences of exposure of biota;

- Measurement of radiation dose: external, internal, biological, and patient dosimetry;

- Numerical and computational dosimetry: mathematical methods and models applied to radiation dosimetry;

- Medical and biomedical image in diagnostic radiology;

- Novel technologies in radiotherapy.

Dr. Miguel Alcaraz
Guest Editor

Manuscript Submission Information

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Keywords

  • ionizing radiation
  • radiation physics
  • radiation detection
  • radiation dosimetry
  • medical and biomedical image in diagnostic radiology
  • radiation effects
  • radiotherapy
  • radiation protection

Published Papers (3 papers)

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Research

8 pages, 1335 KiB  
Article
Usefulness of Elastography for the Evaluation of Subcentimeter Solid Breast Nodules
by Florentina Guzmán-Aroca, Yésica Martínez-Paredes, Juan de Dios Berná-Serna, Ana Azahara García-Ortega, Juan de Dios Berná-Mestre and Miguel Alcaraz
Appl. Sci. 2021, 11(4), 1409; https://0-doi-org.brum.beds.ac.uk/10.3390/app11041409 - 04 Feb 2021
Viewed by 1476
Abstract
The accurate diagnosis of subcentimeter lesions is controversial, and therefore a standardized diagnosis algorithm is needed. The objective of the present work was to study the value of the elastography patterns obtained through the use of the shear wave elastography (SWE) technique with [...] Read more.
The accurate diagnosis of subcentimeter lesions is controversial, and therefore a standardized diagnosis algorithm is needed. The objective of the present work was to study the value of the elastography patterns obtained through the use of the shear wave elastography (SWE) technique with respect to histopathology for the evaluation of nodular breast lesions ≤1 cm. A retrospective study was conducted which included 65 sub-centimeter lesions from 57 patients with an average age of 45.6 ± 11.9. For all the cases, a B-mode ultrasound study, shear wave elastography, and a posterior anatomopathological study were conducted. The lesions had a diameter greater than 7.5 ± 1.7 mm (range: 4–9 mm). Through elastography, the distribution of the patterns was: cyst artifact (n = 13), pattern 1 (n = 4), pattern 2 (n = 31), pattern 3 (n = 13), and pattern 4 (n = 4). Of the 65 lesions, 15 were cysts, 46 were solid benign lesions, and 3 were malignant lesions. The sensitivity of the elastography was 75%, with a specificity of 98.46% and a correct diagnosis in 96.92% of the cases (n = 63). The results from this study show the usefulness of SWE for the evaluation of sub-centimeter breast lesions. In addition, this diagnostic strategy helps with the differential diagnosis between benign and malignant lesions and contributes to the early detection of malignant breast lesions. Full article
(This article belongs to the Special Issue Novel Technologies in Radiology and Radiobiology)
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10 pages, 2021 KiB  
Article
A New Technique for Computed-Tomography Urethrography in Males: The Clamp Method
by Juan de Dios Berná-Mestre, Florentina Guzmán-Aroca, Alejandro Puerta-Sales, Antonio Navarro-Baño, Guillermo Carbonell-López del Castillo, Juan de Dios Berná-Serna and Miguel Alcaraz
Appl. Sci. 2021, 11(3), 1006; https://0-doi-org.brum.beds.ac.uk/10.3390/app11031006 - 22 Jan 2021
Cited by 2 | Viewed by 5155
Abstract
The aim of the present study is to describe and evaluate a new technique for performing Computed-Tomography Retrograde Urethrography (CT-RUG). Males with urethral anomalies detected by retrograde urethrography (RUG) and/or retrograde sonourethrography (RSUG) underwent CT-RUG using the clamp method and three radiologists evaluated [...] Read more.
The aim of the present study is to describe and evaluate a new technique for performing Computed-Tomography Retrograde Urethrography (CT-RUG). Males with urethral anomalies detected by retrograde urethrography (RUG) and/or retrograde sonourethrography (RSUG) underwent CT-RUG using the clamp method and three radiologists evaluated the anomalies in each technique separately and blindly. CT-RUG was done successfully in all the cases (n = 22), with means of 6 min duration and 95 mL of contrast; no pain was reported by 81% of the patients (VAS: 0) and very mild pain by the rest (VAS: 0.5–1.2). CT-RUG showed better diagnostic efficacy in cases of periurethral fistula (n = 8), urethral stent (n = 3), previous urethroplasty and urethral lithiasis (n = 2), a similar accuracy to RSUG for measuring the length of anterior urethral strictures (n = 9) and greater accuracy than RUG (p = 0.008). Six cases received 2 CT sweeps, with an effective dose of 4.96 mSv, and the remaining 16 had 1 sweep and received 3.456 mSv. To the best of our knowledge, this is the first study to describe the clamp method for CT-RUG, a method that is effective and comfortable for both the patient and the operator (retrograde infusion of contrast). Full article
(This article belongs to the Special Issue Novel Technologies in Radiology and Radiobiology)
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12 pages, 2618 KiB  
Article
Galactography Combined with Sonogalactography for Improving the Evaluation of Pathological Nipple Discharge
by Juan de Dios Berná-Serna, Florentina Guzmán-Aroca, César Leal-Costa, Miguel Alcaraz and Juan de Dios Berná-Mestre
Appl. Sci. 2021, 11(1), 327; https://0-doi-org.brum.beds.ac.uk/10.3390/app11010327 - 31 Dec 2020
Cited by 1 | Viewed by 4768
Abstract
Diagnosing patients with pathological nipple discharge (PND) is controversial, and therefore a standardized diagnosis algorithm is needed. The objective of this study was to investigate the usefulness of galactography (GL) combined with sonogalactography (SGL) for the evaluation of PND patients. A retrospective study [...] Read more.
Diagnosing patients with pathological nipple discharge (PND) is controversial, and therefore a standardized diagnosis algorithm is needed. The objective of this study was to investigate the usefulness of galactography (GL) combined with sonogalactography (SGL) for the evaluation of PND patients. A retrospective study was conducted of 51 patients with PND who were evaluated with GL and SGL. The findings from the galactograms of the patients in this study were assigned to different categories of the Galactogram Image Classification System. Additionally, the sensitivity, specificity, and the positive predictive values and negative predictive values of the GL and SGL tests were calculated, considering the gold standard of pathology diagnosis. The results obtained show that GL combined with SGL improved the diagnostic efficiency of ductal lesions, especially for borderline and malignant lesions. Papilloma was diagnosed in 19 cases, and ductal carcinoma in situ in 8 patients. Conclusions: To the best of our knowledge, this is the first study in which the combination of GL and SGL improves the diagnostic efficiency of ductal lesions of patients with PND. A diagnosis algorithm is recommended for women with PND. Full article
(This article belongs to the Special Issue Novel Technologies in Radiology and Radiobiology)
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