The Treatment of Mitral Disease: From the Ring to the Clip

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: closed (31 March 2021) | Viewed by 4547

Special Issue Editor


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Guest Editor
Department of Clinical, Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of Rome, 00161 Rome, Italy
Interests: cardiac surgery; valvulopathy; aortic surgery; minimally invasive cardiac surgery
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Special Issue Information

Dear Colleagues,

This Special Issue, “The treatment of Mitral Disease: From the Ring to the Clip”, will mainly focus on mitral valve disease, diagnosis, and treatment. Mitral valve regurgitation is currently the most frequent valve disorder around the wall and its treatment is developing in different paths, accomplishing a lesser invasive strategy mainly for sicker and older patients. Special attention will be dedicated to the physiopathological and biological mechanism leading to mitral regurgitation and atrial fibrillation. In addition, functional mitral regurgitation (FMR) as a very complex disease, mainly caused by left ventricular dysfunction, resulting from an alteration in the geometry of mitral valve apparatus in the absence of structural abnormalities is of special interest. In this setting, the best treatment is still debatable.   

We cordially invite authors in the field to submit original research or review articles pertaining to this important and fast-progressing field of biomedicine.

Dr. Ernesto Greco
Guest Editor

Manuscript Submission Information

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Keywords

  • cardiac surgery
  • mitral regurgitation
  • imaging
  • interventional devices

Published Papers (2 papers)

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Editorial

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3 pages, 185 KiB  
Editorial
The Treatment of Mitral Valve Disease—The Only Thing Constant is Change
by Joseph Zacharias and Ernesto Greco
Biomedicines 2021, 9(2), 126; https://0-doi-org.brum.beds.ac.uk/10.3390/biomedicines9020126 - 28 Jan 2021
Cited by 1 | Viewed by 1291
Abstract
The mitral valve is without doubt the part of the human body that is most under pressure [...] Full article
(This article belongs to the Special Issue The Treatment of Mitral Disease: From the Ring to the Clip)

Review

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29 pages, 2199 KiB  
Review
Ischemic Mitral Regurgitation: A Multifaceted Syndrome with Evolving Therapies
by Mattia Vinciguerra, Francesco Grigioni, Silvia Romiti, Giovanni Benfari, David Rose, Cristiano Spadaccio, Sara Cimino, Antonio De Bellis and Ernesto Greco
Biomedicines 2021, 9(5), 447; https://0-doi-org.brum.beds.ac.uk/10.3390/biomedicines9050447 - 21 Apr 2021
Cited by 5 | Viewed by 2852
Abstract
Dysfunction of the left ventricle (LV) with impaired contractility following chronic ischemia or acute myocardial infarction (AMI) is the main cause of ischemic mitral regurgitation (IMR), leading to moderate and moderate-to-severe mitral regurgitation (MR). The site of AMI exerts a specific influence determining [...] Read more.
Dysfunction of the left ventricle (LV) with impaired contractility following chronic ischemia or acute myocardial infarction (AMI) is the main cause of ischemic mitral regurgitation (IMR), leading to moderate and moderate-to-severe mitral regurgitation (MR). The site of AMI exerts a specific influence determining different patterns of adverse LV remodeling. In general, inferior-posterior AMI is more frequently associated with regional structural changes than the anterolateral one, which is associated with global adverse LV remodeling, ultimately leading to different phenotypes of IMR. In this narrative review, starting from the aforementioned categorization, we proceed to describe current knowledge regarding surgical approaches in the management of IMR. Full article
(This article belongs to the Special Issue The Treatment of Mitral Disease: From the Ring to the Clip)
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