Cancer Pathogenesis and Progression Impacted by Environmental Factors
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Motility and Adhesion".
Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 6594
Special Issue Editors
Interests: metastasis; molecular pathway; cancer models; metabolism; tumor microenvironment, drug screening and development
Special Issues, Collections and Topics in MDPI journals
Interests: hypoxia; hypoxia-inducible factor; reactive oxygen species; metabolism; growth factor and hormone signaling; kinases; cancer metabolism
Interests: clinical trials; the cancer-diabetes link; environmental factors and human diseases; therapeutic strategy
Interests: hypoxia-inducible factors (HIFs) and hypoxia signaling; therapeutic potential of HIF proline hydroxylase inhibitors; gene regulation; metabolism; molecular pathway; upstream stimulatory factors (USFs); post-translational regulation; Serpine1 (PAI1) regulation
Special Issue Information
Dear Colleagues,
Genetic elements interacting with environmental components can individually and collectively influence one’s susceptibility to cancer. Numerous environmental factors (e.g., nutrition, chemical carcinogens, tobacco/alcohol use, hypoxia, and medical treatments) possess proinvasive and prometastatic features, in addition to tumorigenic properties. In fact, environmental factors may also contribute to a cancer-favorable microenvironment in premetastatic niches and promote cell heterogeneity and plasticity, enhancing metastasis formation. We are still far from fully understanding both the seed and the soil factors involved in cancer development and progression. Further studies are clearly imperative to delineate the significance and enigmatic mechanisms that underline the gain of metastatic potential by tumors from environmental factors and help the development of new approaches to the treatment and prevention of cancer. We kindly invite you to contribute to this Special Issue with original research articles, reviews, or shorter “Perspective” articles on all aspects related to the theme of “Cancer Pathogenesis and Progression Impacted by Environmental Factors”. The purpose of this Special Issue is to provide scientific evidence regarding the mutual interactions between tumor cells and cellular and non-cellular components of the tumor microenvironment, so to increase our understanding of how particular environmental factors increase the risk of developing cancer and their impact cancer onset and progression.
Dr. Yong Teng
Prof. Thomas Kietzmann
Dr. Chloe Shay
Dr. Elitsa Y. Dimova
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- environmental factors
- microenvironment
- metastasis
- molecular interactions
- therapeutics
