Mechanotransduction in Control of Cell Fate and Function
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (30 November 2019) | Viewed by 37812
Special Issue Editors
Interests: adhesion molecules; cellular mechanobiology; mitochondrial dynamics; vesicular trafficking; islet of Langerhans; beta cells differentiation; diabetes mellitus; pancreatic tumors; glia–neuron interactions
Special Issues, Collections and Topics in MDPI journals
Interests: mechanotransduction; cellular mechanobiology; integrins; cell adhesion; cell migration; cell invasion; metastasis; biomaterials; cell-microenvironment interactions; cytoskeleton; cell differentiation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mechanotransduction defines the process by which cells perceive and respond to microenvironmental physical forces (e.g., tension, compression, distortion, friction) and cues (e.g., rigidity, topography) by activating a cellular signaling sequence mediated by mechanosensitive cellular components and gene expression. Although the underlying molecular mechanisms have not been completely understood, increasing evidence suggests that mechanotransduction is critically involved in the control of cell differentiation, tissue homeostasis, and organ development.
This Special Issue welcomes original research and review papers addressing the contribution of biophysical forces and cues deriving from the extracellular microenvironment in shaping stem cell fate. Interdisciplinary applications will stimulate future research in this exciting and rapidly-progressing field.
Prof. Carla Perego
Dr. Carsten Schulte
Guest Editors
Manuscript Submission Information
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Keywords
- mechanotransduction
- stem cells
- regenerative medicine
- extracellular matrix
- biomaterials
- tissue engineering
Related Special Issue
- Mechanotransduction in Cell Functioning and (Patho)physiology in Cells (4 articles)