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Current Research on Cleft Lip in Children - Volume 2
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Current Research on Cleft Lip in Children - Volume 2

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Dentistry".

Deadline for manuscript submissions: 5 June 2024 | Viewed by 5731

Special Issue Editors

Prof. Dr. Thais Marchini Oliveira

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Guest Editor
Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry and Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil
Interests: children with oral clefts and the relation to the rehabilitative progress of children; in terms of medicine; speech; dentistry; physiology; psychology
Special Issues, Collections and Topics in MDPI journals
Dr. Cleide Felício Carvalho Carrara

E-Mail Website
Guest Editor
Department of Pediatric Dentistry, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil
Interests: cleft lip and palate; pediatric dentistry; tooth eruption and orthodontics
Prof. Dr. Maria Aparecida Andrade Moreira Machado

E-Mail Website
Guest Editor
Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry and Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil
Interests: pediatric dentistry
Dr. Paula Karine Jorge

E-Mail Website
Guest Editor
Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry and Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil
Interests: pediatric dentistry; cleft lip and palate; proteome
Dr. Eloá Cristina Passucci Ambrósio

E-Mail Website
Guest Editor
Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry and Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil
Interests: pediatric dentistry; anomalies craniofacial; cleft lip; cleft palate; 3D image

Special Issue Information

Dear Colleagues,

This issue will include papers all about oral clefts. In order to expand the evaluation and management of experimental and theoretical results about aspects of quality of life, growth and development, speech disorders, epidemiological, genetics and environmental factors linked with oral clefts. In order to increase understanding of fundamental principles and biological questions of oral clefts.

Aims

Children (ISSN 2227-9067), Special Issue about Current Research on Cleft Lip in Children is an international, open access journal dedicated to a streamlined, yet scientifically rigorous, dissemination of peer-reviewed science related to children with oral clefts in developed and developing countries.

The publication focuses on sharing clinical, epidemiological and translational science relevant to children with oral clefs. Moreover, the primary goals of the publication are to highlight knowledge about all aspects of children with an oral cleft, such as epidemiological, clinical challenges, etiology, speech disorders, quality of life, growth and development, and related anomalies in order to rehabilitate and reinsert patients into society. In addition to original research, the journal publishes expert editorials and commentaries, clinical case reports, and insightful communications reflecting the latest developments in children with oral clefs. By publishing meritorious articles as soon as the editorial review process is completed, rather than at predefined intervals, Children also permits rapid open access sharing of new information, allowing us to reach the broadest audience in the most expedient fashion.

Scope

Articles in Children include, but are not limited to:

  • Public Health and Epidemiology
  • Growth and Development
    • Maxilla
    • Dental cast
    • Three dimensional imaging
    • Facial profile
    • Relationship maxila and mandible.
  • Pediatric Subspecialties
    • Neurology
    • Developmental/Behavioral Medicine
    • Neonatal/Perinatal Medicine
    • Plastic Surgery
    • Sistemic disorders
  • Quality of life
    • Family relationship
    • Society
    • Patient with oral clefts itself
    •  Psychologic aspects
  • Speech disorders
  • Etiology
    • Genetics
    • Environment
  • Epidemiology
    • General apstects

[*] What kind of papers we are soliciting:

We are receiving papers of Research/ Review/ Case Reports / Short Communication/ Literature review/Systematic Review

Prof. Dr. Thais Marchini Oliveira
Dr. Cleide Felício Carvalho Carrara
Prof. Dr. Maria Aparecida Andrade Moreira Machado
Dr. Paula Karine Jorge
Dr. Eloá Cristina Passucci Ambrósio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral clefts
  • cleft lip and palate
  • growth and development
  • speech disorders
  • quality of life
  • etiology
  • genetics and enviroment factors

Published Papers (5 papers)

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Editorial

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2 pages, 205 KiB  
Editorial
Current Perspectives on Cleft Lip and Palate and Children’s Health
by Paula Karine Jorge, Eloá Cristina Passucci Ambrosio, Yana Cosendey Toledo Mello-Peixoto, Cleide Felício Carvalho Carrara, Simone Soares, Ana Lucia Pompeia Fraga de Almeida, Maria Aparecida Andrade Moreira Machado and Thais Marchini Oliveira
Children 2023, 10(5), 857; https://0-doi-org.brum.beds.ac.uk/10.3390/children10050857 - 11 May 2023
Viewed by 1162
Abstract
Orofacial clefts are the most prevalent craniofacial congenital anomalies, affecting the lip, with or without involvement of the palate, or solely the palate [...] Full article
(This article belongs to the Special Issue Current Research on Cleft Lip in Children - Volume 2)

Research

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12 pages, 937 KiB  
Article
Caregivers’ Experience with Lip Taping as a Presurgical Orthopedic Treatment for Cleft Lip and Palate Defects
by Athar Thair, Mushriq Abid and Arkadiusz Dziedzic
Children 2024, 11(3), 332; https://0-doi-org.brum.beds.ac.uk/10.3390/children11030332 - 10 Mar 2024
Viewed by 909
Abstract
Background: This study aimed to assess caregivers’ experiences and perceptions of applying lip taping as presurgical orthopedic therapy (PSO) for infants with a cleft lip and palate. Methods: A retrospective survey was conducted, inviting parents to respond to a series of structured questions [...] Read more.
Background: This study aimed to assess caregivers’ experiences and perceptions of applying lip taping as presurgical orthopedic therapy (PSO) for infants with a cleft lip and palate. Methods: A retrospective survey was conducted, inviting parents to respond to a series of structured questions between September 2022 and June 2023. The questionnaire focused on evaluating parents’ experience with lip taping, a crucial component of PSO. Descriptive statistics and the Chi-square test were employed to analyze relationships between categorical variables. Results: Of the 157 participants, overall, 122 completed the survey, forming the dataset for analysis. A majority (90.0%) reported sufficient experience in using lip taping and no major difficulties with lip taping application. Caregivers with higher education levels exhibited a significantly positive correlation (p = 0.015). Additionally, 93.4% confirmed the efficacy of lip taping for premaxillary segment retraction, with this outcome being correlated with caregivers’ knowledge and education (p = 0.008). Interestingly, caregivers’ age also demonstrated a substantial association (p = 0.020). Conclusions: While a vast majority expressed positive experiences with lip taping as a presurgical treatment, continuous, tailored education on cleft lip and palate is imperative. This education should be directed towards caregivers and individuals offering direct support to parents of children with CLP, ensuring optimal care and preparation for surgical treatment. Full article
(This article belongs to the Special Issue Current Research on Cleft Lip in Children - Volume 2)
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13 pages, 287 KiB  
Article
A Cross-Sectional Study of the Dental Arch Relationship and Palatal Morphology after Cleft Surgery in Italian Children with Unilateral Cleft and Lip Palate
by Patrizia Defabianis, Rosa Guagnano and Federica Romano
Children 2023, 10(9), 1559; https://0-doi-org.brum.beds.ac.uk/10.3390/children10091559 - 15 Sep 2023
Viewed by 717
Abstract
Dental arch relationships (DARs) and palatal morphology (PM) were evaluated in in non-syndromic complete unilateral cleft lip and palate (UCLP) Italian patients after surgery. Pre- and postnatal factors affecting the results were investigated. Sixty-six children with UCLP (40 boys and 26 girls, with [...] Read more.
Dental arch relationships (DARs) and palatal morphology (PM) were evaluated in in non-syndromic complete unilateral cleft lip and palate (UCLP) Italian patients after surgery. Pre- and postnatal factors affecting the results were investigated. Sixty-six children with UCLP (40 boys and 26 girls, with a mean age of 10.1 ± 2.9 years), predominantly Caucasian (77%), were consecutively enrolled in this cross-sectional study. Twenty children had received a one-stage protocol consisting of an early periosteal palate surgical repair and lip closure and forty-six were submitted to a staged surgical protocol with delayed palate repair (DPR). A single clinician collected data on their medical history and carried out a dental examination. The DAR and PM were graded on dental casts according to the Eurocran index and dichotomised as favourable and unfavourable based on the treatment outcome. Multiple logistic regression analyses demonstrated that female sex (OR = 6.08, 95% CI: 1.47–25.23, p = 0.013), DPR (OR = 4.77, 95% CI: 1.14–19.93, p = 0.032) and the use of a neonatal plate (OR = 4.68, 95% CI: 1.27–17.16, p = 0.020) increased the odds of having favourable DAR, while only DPR (OR = 9.76, 95% CI: 2.40–39.71, p = 0.001) was significantly associated with a favourable PM. Based on these findings, only DPR had a significantly favourable effect on both DAR and DM in Italian children with complete UCLP. Full article
(This article belongs to the Special Issue Current Research on Cleft Lip in Children - Volume 2)

Review

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11 pages, 657 KiB  
Review
Effect of Maxillary Expansion on the Maxillary Arch Width in Patients with Bilateral Cleft Palate: A Review
by Omar H. Alkadhi, Lamis Hejab Alotaibi, Rowaida R. Alrashoud, Mohammed Hamad Almutairi, Huda Ali Al Matar and Sreekanth Kumar Mallineni
Children 2023, 10(5), 762; https://0-doi-org.brum.beds.ac.uk/10.3390/children10050762 - 23 Apr 2023
Viewed by 1576
Abstract
Objectives: To perform a comprehensive review of the literature to compare the effects of slow maxillary expansion (SME) and rapid maxillary expansion (RME) on maxillary arch width in patients with bilateral cleft palate. Methods: The databases include Medline, PubMed, Cochrane (CENTRAL) and (CDSR), [...] Read more.
Objectives: To perform a comprehensive review of the literature to compare the effects of slow maxillary expansion (SME) and rapid maxillary expansion (RME) on maxillary arch width in patients with bilateral cleft palate. Methods: The databases include Medline, PubMed, Cochrane (CENTRAL) and (CDSR), OpenGrey, and ClinicalTrials.gov were searched for relevant studies that met the eligibility criteria published before or on 31 October 2022. The search was confined to the English language. The selection of eligible studies and collection of data were performed independently. Risk of bias assessment was conducted using the Cochrane Risk of Bias tool 2.0. Results: Two randomized controlled trials were available based on the search in the published literature. Both studies compared arch width between SME and RME in cleft palate patients and digitals casts and three-dimensional images used for the evaluation. A moderate risk of bias was evident in the available studies. Conclusions: Both SME and RME can achieve similar amounts of maxillary expansion in patients with bilateral cleft palate. Full article
(This article belongs to the Special Issue Current Research on Cleft Lip in Children - Volume 2)
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Other

19 pages, 777 KiB  
Systematic Review
Clinician- and Patient-Centred Outcomes of Digital Impressions in Infants with Cleft Lip and Palate: A Systematic Review
by Jyotsna Unnikrishnan, Yasaman Etemad Shahidi, Mahmoud Bakr, Robert Love and Ghassan Idris
Children 2024, 11(3), 343; https://0-doi-org.brum.beds.ac.uk/10.3390/children11030343 - 13 Mar 2024
Viewed by 766
Abstract
This systematic review examines the effectiveness of digital impressions in infants with cleft lip and palate (CLP), focusing on accuracy, operator preferences, and parents’ perceptions. The PICO-formulated focused questions assessed the accuracy and operator preference of digital impressions compared to conventional impressions in [...] Read more.
This systematic review examines the effectiveness of digital impressions in infants with cleft lip and palate (CLP), focusing on accuracy, operator preferences, and parents’ perceptions. The PICO-formulated focused questions assessed the accuracy and operator preference of digital impressions compared to conventional impressions in infants with cleft lip and palate, while also exploring parents’ perceptions as patient-centred outcomes. Electronic and manual searches were conducted in five databases including PubMed, Scopus, Web of Science, Embase, and Cochrane Library; to acquire grey literature, Google Scholar was also consulted. Both experimental and observational studies that used digital impressions in the clinical care of infants with CLP were included. The Joanna Briggs Institute Critical Appraisal Checklist was used to assess the quality of the included studies. Out of 503 records, 12 studies met the inclusion criteria. The accuracy assessment included surface discrepancy and intra-arch measurements. Surface discrepancy studies showed variations in the premaxillary segments, while intra-arch measurements revealed no significant differences. Operators preferred digital impressions, citing reduced stress and streamlined workflows. Parents expressed a clear preference for digital over conventional impressions. The conclusions drawn were substantiated by weak evidence due to the limited number and the high risk of bias of the included studies. Challenges remain here, warranting continued research to enhance accuracy and assess parents’ preferences, ensuring optimal outcomes for infants with CLP. Full article
(This article belongs to the Special Issue Current Research on Cleft Lip in Children - Volume 2)
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