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Children
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Pediatric Rheumatology Diseases: Cutting-Edge Research on Therapeutic Approaches
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Pediatric Rheumatology Diseases: Cutting-Edge Research on Therapeutic Approaches

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Allergy and Immunology".

Deadline for manuscript submissions: closed (5 December 2023) | Viewed by 1499

Special Issue Editors

Dr. Angela Mauro

E-Mail Website
Guest Editor
Rheumatology Unit, Department of Pediatrics, ASST Fatebenefratelli-Sacco, Milan, Italy
Interests: multisystem inflammatory syndrome; COVID-19; pediatric rheumatology; children
Dr. Teresa Giani

E-Mail Website
Guest Editor
Pediatric Rheumatology, Anna Meyer Children’s University Hospital, 50139 Florence, Italy
Interests: juvenile idiopathic arthritis; systemic lupus erythematosus; pediatric vasculitis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

I’m serving as Guest Editor for a new article collection for Children (ISSN 2227-9067, IF 2,863), entitled “Pediatric Rheumatology Diseases: New Advances in Therapeutic Approaches”.

The incidence of rheumatological diseases in children has increased significantly. Very often, unfortunately, the therapies available are not effective, with serious consequences in terms of mortality and morbidity. Clinicians often treat these patients with off-label drugs. For this reason, it would be very useful to highlight the effectiveness of new therapeutic strategies in order to help clinicians in the treatment of rheumatological pathologies refractory to standard therapies.

We are interested in original articles, reviews, case reports/case series that describe an original aspect or evident therapeutic advances in these diseases.

The submission deadline is 20 March 2023. We look forward to your contributions.

Dr. Angela Mauro
Dr. Teresa Giani
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • children
  • pediatric rheumatology
  • off-label
  • therapy
  • treatment

Published Papers (1 paper)

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8 pages, 4153 KiB  
Case Report
Severe Juvenile-Onset Systemic Lupus Erythematosus: A Case Series-Based Review and Update
by Sergi Huerta-Calpe, Ignacio Del Castillo-Velilla, Aida Felipe-Villalobos, Iolanda Jordan and Lluïsa Hernández-Platero
Children 2023, 10(5), 852; https://0-doi-org.brum.beds.ac.uk/10.3390/children10050852 - 10 May 2023
Viewed by 1115
Abstract
Juvenile-onset systemic lupus erythematosus (jSLE) is a multisystemic disease diagnosed in young patients based on the clinical criteria of the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR). The importance of this condition lies in its greater aggressiveness compared [...] Read more.
Juvenile-onset systemic lupus erythematosus (jSLE) is a multisystemic disease diagnosed in young patients based on the clinical criteria of the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR). The importance of this condition lies in its greater aggressiveness compared with lupus diagnosed during adulthood (aSLE). Management, which is based on supportive care and immunosuppressive drugs, aims to reduce the overall disease activity and to prevent exacerbation. Sometimes the onset is accompanied by life-threatening clinical conditions. In this paper, we introduce three recent cases of jSLE that required admission to the Pediatric Intensive Care Unit (PICU) of a Spanish pediatric hospital. This manuscript aims to review some of the main complications associated with jSLE, such as diffuse alveolar hemorrhage, cerebral vasculitis, or an antiphospholipid syndrome; these are life-threatening conditions but they have a chance of favorable prognosis if treated early and aggressively. Full article
(This article belongs to the Special Issue Pediatric Rheumatology Diseases: Cutting-Edge Research on Therapeutic Approaches)
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