Aquaculture Vaccine Development: Disease Control and Prevention

A special issue of Fishes (ISSN 2410-3888). This special issue belongs to the section "Welfare, Health and Disease".

Deadline for manuscript submissions: closed (30 September 2022) | Viewed by 3582

Special Issue Editor


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Guest Editor
Department of Marine Bio and Medical Sciences, Hanseo University, Seosan-si, Republic of Korea
Interests: aquatic animal disease; immunology; disease control and prevention

Special Issue Information

Dear Colleagues,

Over the past few decades, the global aquaculture industry has achieved remarkable growth through diversification is species and culture systems. However, with the fast growth in aquaculture industry, the incidence of aquatic diseases are gradually increasing due to existing and emerging pathogens. Additionally, the change in global climate has increased the frequency of diseases due to variation in temperature. The transboundary movement of migratory fishes and other aquatic animals, the movement of live fishes for international trade has introduced the risk of transboundary diseases. Hence, efforts are needed to minimize the damage to aquaculture industry due to diseases. This special issue aims to cover a broad spectrum of research on aquaculture vaccine development for disease prevention and control. We invite you to submit research papers on the recent advances in disease control, disease prevention, therapy, immunostimulants, and vaccinology, as well as groundbreaking concepts in host-pathogen interaction, immune defense mechanism, and disease mechanism relevant to the protection of fish against diseases. We look forward to publishing your latest research with new exciting findings on aquaculture vaccine development and disease prevention and control.

Dr. Myung-Hwa Jung
Guest Editor

Manuscript Submission Information

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Keywords

  • vaccines
  • immunostimulants
  • disease control and prevention
  • therapy
  • disease mechanism
  • host-pathogen interaction
  • immune defense mechanism

Published Papers (1 paper)

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Research

18 pages, 2442 KiB  
Article
Oral Administration of Probiotics (Bacillus subtilis and Lactobacillus plantarum) in Nile Tilapia (Oreochromis niloticus) Vaccinated and Challenged with Streptococcus agalactiae
by Mateus Cardoso Guimarães, Isabel M. Cerezo, Miguel Frederico Fernandez-Alarcon, Mariene Miyoko Natori, Luciana Yuri Sato, Camila A. T. Kato, Miguel Angel Moriñigo, Silvana Tapia-Paniagua, Danielle de Carla Dias, Carlos Massatoshi Ishikawa, Maria José T. Ranzani-Paiva, Luara Lucena Cassiano, Erna Elisabeth Bach, Patrícia B. Clissa, Daniele P. Orefice and Leonardo Tachibana
Fishes 2022, 7(4), 211; https://0-doi-org.brum.beds.ac.uk/10.3390/fishes7040211 - 22 Aug 2022
Cited by 3 | Viewed by 3127
Abstract
Streptococcus agalactiae is an important bacterial pathogen in intensive Nile tilapia production, causing high mortality rates and great economic losses. This work aimed to evaluate the Nile tilapia vaccination against S. agalactiae and fed with ration containing probiotic AQUA PHOTO® composed of [...] Read more.
Streptococcus agalactiae is an important bacterial pathogen in intensive Nile tilapia production, causing high mortality rates and great economic losses. This work aimed to evaluate the Nile tilapia vaccination against S. agalactiae and fed with ration containing probiotic AQUA PHOTO® composed of Bacillus subtilis and Lactobacillus plantarum, on the immune response action and gut microbiota. The experimental design was completely randomized with five treatments (CON = control; ADJ = adjuvant; PRO = probiotic; VAC = vaccine; PRO + VAC = probiotic + vaccine) and five replicates. The vaccine (bacterin + adjuvant) was injected after 21 days (21d) of probiotic feeding and the vaccine was booster 14 days post-vaccination (35d). After 14 days of the booster (49d), the fish were challenged with S. agalactiae and observed for more than 14 days, completing 63 days. The immunized group showed a better survival rate (CON 40%; ADJ 57%; PRO 67%; VAC 87%; PRO + VAC 97%). The treatments VAC and PRO + VAC, after booster produced higher levels of IgM antibodies compared with the control from the same time. The combination of probiotic and vaccination provided better protection against S. agalactiae infection, directly affecting the gut microbiological profile. These results indicated the contribution of probiotic to the adaptive immune response through the modulation of the intestinal microbiota, improving the effect of the vaccination. In conclusion, AQUA PHOTO®, composed of B. subtilis and L. plantarum, orally administered to Nile tilapia vaccinated against and challenged with S. agalactiae increases protection from infection and modifies the intestinal microbiota profile of the host, promoting the microbiota balance and improving adaptive immune response. Full article
(This article belongs to the Special Issue Aquaculture Vaccine Development: Disease Control and Prevention)
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