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Nanotechnology to the Benefit of Environment and Public Health

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601).

Deadline for manuscript submissions: closed (30 June 2020) | Viewed by 24814

Special Issue Editor

Special Issue Information

Dear Colleagues,

“Nanotechnology is the application of science to control matter at the molecular level”. It has become one of the most promising technologies applied in all areas of science. Nanoparticles have multifunctional properties and very interesting applications in various fields, such as medicine, nutrition, energy, agriculture, and the environment. The biogenic syntheses of monodispersed nanoparticles with specific sizes and shapes have been a challenge in biomaterial science. Nanoparticles are of great interest due to their extremely small size and large surface to volume ratio, which lead to both chemical and physical differences in their properties (e.g., mechanical properties, biological and sterical properties, catalytic activity, thermal and electrical conductivity, optical absorption and melting point) compared to bulk of the same chemical composition. Recently, synthesizing metal nanoparticles using green technology via microorganisms, plants, viruses, etc. has been extensively studied and has been recognized as a green and efficient way to further exploit biological systems as convenient nanofactories. The biological synthesis of nanoparticles is increasingly regarded as a rapid, ecofriendly, and easily scaled-up technology. At present, researchers want to develop new techniques and materials using nanotechnology that could be suitable for plants to boost their native functions. Recently, biological nanoparticles were found to be more pharmacologically active than physicochemically synthesized nanoparticles. There are various applications of biosynthesized nanoparticles, especially in the field of biomedical research (application in specific delivery of drugs, such as paclitaxel, methotrexate, and doxorubicin; used for tumor detection, angiogenesis, genetic disease and genetic disorder diagnosis, photoimaging, and photothermal therapy). Further, iron oxide nanoparticles have been applied in cancer therapy, hyperthermia, drug delivery, tissue repair, cell labeling, targeting and immunoassays, detoxification of biological fluids, magnetic resonance imaging, magnetically responsive drug delivery therapy, etc. Similarly, the application of nanotechnology in agriculture and food have also gained great importance in recent years in view of its potential application in the development of novel and healthier food. The main driving principle behind these developments seems to be aimed at enhancing uptake and bioavailability of nano-sized nutrients and supplements and improving taste, consistency, stability, texture and safety of food products, nanodelivery systems for bioactive compounds, etc. Therefore, nanotechnology has large potential to provide an opportunity for the researchers of plant science and other fields, to develop new tools for synthesis of environmentally-friendly and cost-effective nanoparticles for their applications in various fields.

This Special Issue seeks research/review papers on various aspects of nanotechnology and their potential applications in the environment/food/pharmacology and biomedical fields for the benefit of the environment and humankind. We particularly encourage the submission of interdisciplinary work and multicountry collaborative research. We welcome original research papers using different study designs as well as systematic reviews and meta-analysis.

Dr. Jayanta Kumar Patra
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Nanoparticle synthesis using green technology and their biomedical applications
  • Use of nanotechnology for the benefit of environment
  • Application of nanotechnology in food production and processing
  • Nanofertilizers and nanosensor applications in the environment
  • Nano-biosensors in environmental monitoring and applications
  • Green synthesis of nanoparticles and their biological applications
  • Nanotechnology and targeted drug delivery system

Published Papers (2 papers)

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Review

32 pages, 4433 KiB  
Review
Triple-Negative Breast Cancer: A Review of Conventional and Advanced Therapeutic Strategies
by Mauricio A. Medina, Goldie Oza, Ashutosh Sharma, L.G. Arriaga, José Manuel Hernández Hernández, Vincent M. Rotello and Jose Tapia Ramirez
Int. J. Environ. Res. Public Health 2020, 17(6), 2078; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph17062078 - 20 Mar 2020
Cited by 163 | Viewed by 19029
Abstract
Triple-negative breast cancer (TNBC) cells are deficient in estrogen, progesterone and ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to their highly invasive nature and relatively low response to therapeutics. There is an absence of specific treatment strategies for this tumor [...] Read more.
Triple-negative breast cancer (TNBC) cells are deficient in estrogen, progesterone and ERBB2 receptor expression, presenting a particularly challenging therapeutic target due to their highly invasive nature and relatively low response to therapeutics. There is an absence of specific treatment strategies for this tumor subgroup, and hence TNBC is managed with conventional therapeutics, often leading to systemic relapse. In terms of histology and transcription profile these cancers have similarities to BRCA-1-linked breast cancers, and it is hypothesized that BRCA1 pathway is non-functional in this type of breast cancer. In this review article, we discuss the different receptors expressed by TNBC as well as the diversity of different signaling pathways targeted by TNBC therapeutics, for example, Notch, Hedgehog, Wnt/b-Catenin as well as TGF-beta signaling pathways. Additionally, many epidermal growth factor receptor (EGFR), poly (ADP-ribose) polymerase (PARP) and mammalian target of rapamycin (mTOR) inhibitors effectively inhibit the TNBCs, but they face challenges of either resistance to drugs or relapse. The resistance of TNBC to conventional therapeutic agents has helped in the advancement of advanced TNBC therapeutic approaches including hyperthermia, photodynamic therapy, as well as nanomedicine-based targeted therapeutics of drugs, miRNA, siRNA, and aptamers, which will also be discussed. Artificial intelligence is another tool that is presented to enhance the diagnosis of TNBC. Full article
(This article belongs to the Special Issue Nanotechnology to the Benefit of Environment and Public Health)
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21 pages, 1276 KiB  
Review
The Sustainability Challenge of Food and Environmental Nanotechnology: Current Status and Imminent Perceptions
by Gitishree Das, Jayanta Kumar Patra, Spiros Paramithiotis and Han-Seung Shin
Int. J. Environ. Res. Public Health 2019, 16(23), 4848; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph16234848 - 02 Dec 2019
Cited by 14 | Viewed by 5136
Abstract
Nanotechnology is a connection among various branches of science with potential applications that extend over a variety of scientific disciplines, particularly in the food science and technology fields. For nanomaterial applications in food processing, such as antimicrobials on food contact surfaces along with [...] Read more.
Nanotechnology is a connection among various branches of science with potential applications that extend over a variety of scientific disciplines, particularly in the food science and technology fields. For nanomaterial applications in food processing, such as antimicrobials on food contact surfaces along with the improvement of biosensors, electrospun nanofibers are the most intensively studied ones. As in the case of every developing skill, an assessment from a sustainability point of view is necessary to address the balance between its benefits to civilization and the unwanted effects on human health and the environment. The current review aimed to provide an update regarding the sustainability of current nanotechnology applications in food science technology, environment, and public health together with a risk assessment and toxicity evaluation. Full article
(This article belongs to the Special Issue Nanotechnology to the Benefit of Environment and Public Health)
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