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Tuberculosis, Lung Infection and Public Health
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Tuberculosis, Lung Infection and Public Health

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Infectious Disease Epidemiology".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 5884

Special Issue Editor

Prof. Dr. Giovanni Sotgiu

E-Mail Website
Guest Editor
Clinical Epidemiology and Medical Statistics Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100 Sassari, Italy
Interests: tuberculosis; NTM; respiratory infections; epidemiology; medical statistics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

A Special Issue entitled “Tuberculosis, Lung Infection and Public Health " in the International Journal of Environmental Research and Public Health is being planned. For detailed information on the journal, please use the following link: https://0-www-mdpi-com.brum.beds.ac.uk/journal/ijerph.

Tuberculosis (TB) is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis generally affects the lung and cause severe lung infection, but can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. About 10% of latent infections progress to active disease which, if left untreated, kills about half of those affected. Typical symptoms of active TB are a chronic cough with blood-containing mucus, fever, night sweats and weight loss. It was historically called consumption due to the weight loss. Infection of other organs can cause a wide range of symptoms. Tuberculosis has caused serious harm to global public health.

We invite clinical, epidemiological and translational research papers and reviews which examine the clinically relevant aspects of tuberculosis and other lung diseases. Manuscripts that deal with the epidemiology (transmission, diagnosis, treatment and prevention) of tuberculosis and its related lung infection are very welcome. We will also evaluate other types of articles, such as systematic reviews (and meta-analyses) and commentaries.

Prof. Dr. Giovanni Sotgiu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Tuberculosis
  • Lung infection
  • Infectious disease
  • Mycobacterium tuberculosis (MTB) bacterial infection
  • Public health

Published Papers (3 papers)

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Research

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14 pages, 713 KiB  
Article
The Triple Burden of Tuberculosis, Human Immunodeficiency Virus and Silicosis among Artisanal and Small-Scale Miners in Zimbabwe
by Dingani Moyo, Ronald Ncube, Fungai Kavenga, Lilian Chikwava, Tawanda Mapuranga, Nathan Chiboyiwa, Chipo Chimunhu, Frank Mudzingwa, Orippa Muzvidziwa, Petronella Ncube, Tariro Christwish Mando, Florence Moyo, Blessings Chigaraza, Hellen Masvingo and Collins Timire
Int. J. Environ. Res. Public Health 2022, 19(21), 13822; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph192113822 - 24 Oct 2022
Cited by 8 | Viewed by 1876
Abstract
Artisanal and small-scale mining is characterized by an excessive exposure to silica-containing dust, overcrowding, poor living conditions and limited access to primary health services. This poses a risk to tuberculosis, HIV infection and silicosis. The main purpose of the study is to evaluate [...] Read more.
Artisanal and small-scale mining is characterized by an excessive exposure to silica-containing dust, overcrowding, poor living conditions and limited access to primary health services. This poses a risk to tuberculosis, HIV infection and silicosis. The main purpose of the study is to evaluate the burden of tuberculosis, HIV and silicosis among artisanal and small-scale miners. We conducted a cross sectional study on 3821 artisanal and small-scale miners. We found a high burden of silicosis (19%), tuberculosis (6.8%) and HIV (18%) in a relatively young population, with the mean age of 35.5 years. Men were 1.8 times more likely to be diagnosed with silicosis compared to women, adjusted prevalence ratio [aPR = 1.75 (95% CI: 1.02–2.74)]. Artisanal and small-scale miners who were living with HIV were 1.25 times more likely to be diagnosed with silicosis compared to those who were negative, [aPR = 1.25 (1.00–1.57)]. The risk of silicosis increased with both duration as a miner and severity of exposure to silica dust. The risk of tuberculosis increased with the duration as a miner. Zimbabwe is currently experiencing a high burden of TB, silicosis and HIV among artisanal and small-scale miners. Multi-sectoral and innovative interventions are required to stem this triple epidemic in Zimbabwe. Full article
(This article belongs to the Special Issue Tuberculosis, Lung Infection and Public Health)
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13 pages, 362 KiB  
Article
Effects of Simulated Laughter Therapy Using a Breathing Exercise: A Study on Hospitalized Pulmonary Tuberculosis Patients
by Kwang-Sim Jang, Jeong-Eun Oh and Gyeong-Suk Jeon
Int. J. Environ. Res. Public Health 2022, 19(16), 10191; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph191610191 - 17 Aug 2022
Cited by 1 | Viewed by 1954
Abstract
This study evaluated the effects of simulated laughter therapy on physical symptoms, pulmonary function, depression, and health-related quality of life (HRQOL) among pulmonary tuberculosis patients. This quasi-experimental study assigned tuberculosis patients of hospital A to a laughter group (n = 26) and [...] Read more.
This study evaluated the effects of simulated laughter therapy on physical symptoms, pulmonary function, depression, and health-related quality of life (HRQOL) among pulmonary tuberculosis patients. This quasi-experimental study assigned tuberculosis patients of hospital A to a laughter group (n = 26) and those of hospital B to a control group (n = 26). The eight-week laughter therapy, held twice a week in a 60-min group session, included laughter, entertainment, music-related chorusing, breathing exercises, and meditation. The values of physical symptoms, pulmonary function, depression, and HRQOL from before and after the therapy were analyzed using the paired t-test and the Mann–Whitney U-test. To verify group differences between the experiment and control group, the Wilcoxon signed-rank test and the analysis of covariance (ANCOVA) were employed. Unlike the control group, laughter therapy decreased physical symptoms (t = 7.30, p < 0.01) and increased pulmonary function (t = −3.77, p < 0.01). Psychological health also improved, including depression (t = 10.46, p < 0.01) and HRQOL (t = −9.31, p < 0.01) in the experimental group but not in the control group. Group differences of changes in physical symptoms, pulmonary function, depression, and HRQOL were also significant. Simulated laughter therapy can help moderate depression and physical symptoms and enhance pulmonary function among tuberculosis patients. Full article
(This article belongs to the Special Issue Tuberculosis, Lung Infection and Public Health)

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6 pages, 611 KiB  
Case Report
Subacute Cardiac Tamponade Due to Tuberculous Pericarditis Diagnosed by Urine Lipoarabinomannan Assay in a Immunocompetent Patient in Oyam District, Uganda: A Case Report
by Elda De Vita, Francesco Vladimiro Segala, James Amone, Kabuga Samuel, Claudia Marotta, Giovanni Putoto, Ritah Nassali, Peter Lochoro, Davide Fiore Bavaro, Jerry Ictho, Samuel Okori, Francesco Di Gennaro and Annalisa Saracino
Int. J. Environ. Res. Public Health 2022, 19(22), 15143; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph192215143 - 17 Nov 2022
Cited by 3 | Viewed by 1498
Abstract
Background: Uganda ranks among the countries with the highest burden of TB the world and tuberculous pericarditis (TBP) affects up to 2% of people diagnosed with pulmonary tuberculosis worldwide. In Africa, it represents the most common cause of pericardial disease. Here, we present [...] Read more.
Background: Uganda ranks among the countries with the highest burden of TB the world and tuberculous pericarditis (TBP) affects up to 2% of people diagnosed with pulmonary tuberculosis worldwide. In Africa, it represents the most common cause of pericardial disease. Here, we present the case of a 21-year-old male patient who was diagnosed of cardiac tamponade due to tuberculous pericarditis with a positive urine LF-LAM. Case report: We report a case of a 21-year-old male living in Oyam district, Uganda, who presented to the emergency department with difficulty in breathing, easy fatigability, general body weakness, and abdominal pain. A chest X-ray showed the presence of right pleural effusion and massive cardiomegaly. Thus, percutaneous pericardiocentesis was performed immediately and pericardial fluid resulted negative both for gram staining and real-time PCR test Xpert MTB/RIF. The following day’s urine LF-LAM test resulted positive, and antitubercular therapy started with gradual improvement. During the follow-up visits, the patient remained asymptomatic, reporting good compliance to the antitubercular therapy. Conclusion: Our case highlights the potential usefulness of a LF-LAM-based diagnostic approach, suggesting that, in low-resource settings, this test might be used as part of routine diagnostic workup in patients with pericardial disease or suspected extra-pulmonary tuberculosis. Full article
(This article belongs to the Special Issue Tuberculosis, Lung Infection and Public Health)
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