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Chronic Kidney Disease: Epidemiology and Disparities

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A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Behavior, Chronic Disease and Health Promotion".

Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 9992

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Special Issue Editors

Dr. Tanjala S. Purnell

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Guest Editor

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Interests: health equity; community engagement; kidney transplantation; epidemiology; disparities

Dr. Dinushika Mohottige

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Guest Editor

Department of Medicine, Duke Universty School of Medicine, Durham, NC 27701, USA
Interests: nephrology; transplantation; medical trust; shared decision making

Dr. Dinee C. Simpson

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Guest Editor

Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Interests: transplantation; health equity; diversity; inclusion; kidney disease; structural racism

Special Issue Information

Dear Colleagues,

Effective solutions are needed to combat longstanding inequities in the burden of chronic kidney disease across populations. Socially at-risk individuals in the US and other nations (e.g., racial and ethnic minorities) experience disproportionately high prevalence and rapid progression of chronic kidney disease (CKD). Although many mechanisms have been postulated to explain these disparities, including genetic risk factors and the disproportionate burden of underlying co-morbidities (i.e., diabetes and hypertension), less attention has been given to key social drivers of kidney health inequity, including structural racism and its downstream manifestations (e.g., wealth and income inequality, disproportionate burden of housing and food insecurity). More research is also needed to understand the ways in which exposure to structural forms of racism or marginalization have become embodied in kidney health inequity over the life course (e.g., via gene–environment interactions, allostatic load, etc.).

We are calling for papers that advance theory and evidence to better understand the mechanisms through which structural racism and other social determinants of health impact disparities in chronic kidney disease burden, progression, and access to transplantation. Studies may include original science or review articles that span the life course perspective (from in utero to the care of older adults), and involve multidisciplinary collaborations, such as those in the fields of nephrology, epidemiology, environmental justice, sociology, community-based research, urban health, and global health.

Dr. Tanjala S. Purnell
Dr. Dinushika Mohottige
Dr. Dinee C. Simpson
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

kidney health equity
health disparities
anti-racism
nephrology
environmental justice

Published Papers (4 papers)

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Research

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12 pages, 1107 KiB

Open AccessArticle

Disease Burden of the Kidney Disabled in Korea, 2009–2013: The Gap with That of the Non-Kidney Disabled Continues

by Sun-Mi Shin and Hee-Woo Lee

Int. J. Environ. Res. Public Health 2022, 19(1), 249; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph19010249 - 27 Dec 2021

Cited by 1 | Viewed by 1886

Abstract

Kidney disability due to kidney failure could be considered to be the most severe of all the internal-organ disabilities. The purpose of this study was to identify the disease burden between the kidney and non-kidney disabled among the internal-organ disabled, based on the number of chronic diseases, annual out-of-pocket expenditure, and quality of life. From 2009 to 2013, 308 people (6.5%) with internal-organ disabilities were extracted out of 4732 people with disabilities in the Korea Health Panel. We compared the disease burden of 136 people with kidney disability (44.2%) and 172 people with non-kidney disability (55.8%), and confirmed the trend of disease burden over five years through panel analysis. The disease burden gap between kidney and non-kidney disabilities was, respectively, the number of chronic diseases (4.7 vs. 3.3, p < 0.0001), annual out-of-pocket expenditure ($1292 vs. $847, p < 0.004), and quality of life score out of 100 (49.2 vs. 60.2, p < 0.0001). In addition, when looking at the five-year trend of the three disease burden indexes, the kidney disabled were consistently worse than the non-kidney disabled (p < 0.01). In conclusion, health policy planners aiming for health equity need to seek practical strategies to reduce the gap in the disease burden among people with disabilities. Full article

(This article belongs to the Special Issue Chronic Kidney Disease: Epidemiology and Disparities)

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14 pages, 4996 KiB

Open AccessArticle

Religious Service Attendance and Mortality among Adults in the United States with Chronic Kidney Disease

by Marino A. Bruce, Roland J. Thorpe, Jr., Dulcie Kermah, Jenny Shen, Susanne B. Nicholas, Bettina M. Beech, Delphine S. Tuot, Elaine Ku, Amy D. Waterman, Kenrik Duru, Arleen Brown and Keith C. Norris

Int. J. Environ. Res. Public Health 2021, 18(24), 13179; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph182413179 - 14 Dec 2021

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Abstract

Religion and related institutions have resources to help individuals cope with chronic conditions, such as chronic kidney disease (CKD). The purpose of this investigation is to examine the association between religious service attendance and mortality for adults with CKD. Data were drawn from NHANES III linked to the 2015 public use Mortality File to analyze a sample of adults (n = 3558) who had CKD as defined by a single value of estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m² using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation and/or albumin-to-creatinine ratio ≥17 mg/g for males or ≥25 for females. All-cause mortality was the primary outcome and religious service attendance was the primary independent variable. Cox proportional hazards models were estimated to determine the association between religious service attendance and mortality. The mortality risks for participants who attended a service at least once per week were 21% lower than their peers with CKD who did not attend a religious service at all (HR 0.79; CI 0.64–0.98). The association between religious service attendance and mortality in adults with CKD suggest that prospective studies are needed to examine the influence of faith-related behaviors on clinical outcomes in patients with CKD. Full article

(This article belongs to the Special Issue Chronic Kidney Disease: Epidemiology and Disparities)

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11 pages, 363 KiB

Open AccessArticle

Gender-Specific Differences in Self-Care, Treatment-Related Symptoms, and Quality of Life in Hemodialysis Patients

by Claudia Lerma, Larissa I. Lima-Zapata, Jorge A. Amaya-Aguilar, Itzel Leonardo-Cruz, Monica Lazo-Sánchez, Luis A. Bermúdez, Héctor Pérez-Grovas, Abel Lerma and Julio César Cadena-Estrada

Int. J. Environ. Res. Public Health 2021, 18(24), 13022; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph182413022 - 10 Dec 2021

Cited by 3 | Viewed by 2563

Abstract

Gender and sex differences affect women with kidney failure (KF) negatively at all stages of the disease. This study assessed gender differences in self-care, hemodialysis symptoms, and quality of life in a sample of 102 adult KF patients treated with hemodialysis, from two clinical centers in Mexico. Self-care agency, quality of life, and the symptoms related to hemodialysis were evaluated through questionnaires, and sociodemographic and laboratory variables were obtained from the clinical records. Compared to male patients, female patients reported similar self-care, lower quality of life subscales (symptoms, physical functioning, pain, and overall health), and higher prevalence and intensity of hemodialysis symptoms. There were gender differences regarding the correlation between self-care and quality of life, symptoms intensity, and symptoms prevalence. In conclusion, women with KF treated with hemodialysis perceived a higher impact of hemodialysis and reported a lower quality of life than men. Despite having a similar self-care agency, the self-care correlations with quality of life and hemodialysis symptoms appeared different between men and women treated with chronic hemodialysis. Such differences may be important in future nursing interventions to improve self-care and quality of life among KF patients. Full article

(This article belongs to the Special Issue Chronic Kidney Disease: Epidemiology and Disparities)

Other

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12 pages, 563 KiB

Open AccessProtocol

Women’s Access to Kidney Transplantation in France: A Mixed Methods Research Protocol

by Latame Adoli, Maxime Raffray, Valérie Châtelet, Cécile Vigneau, Thierry Lobbedez, Fei Gao, Florian Bayer, Arnaud Campéon, Elsa Vabret, Laëtitia Laude, Jean-Philippe Jais, Eric Daugas, Cécile Couchoud and Sahar Bayat

Int. J. Environ. Res. Public Health 2022, 19(20), 13524; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph192013524 - 19 Oct 2022

Cited by 2 | Viewed by 2067

Abstract

Kidney transplantation is the best renal replacement therapy (medically and economically) for eligible patients with end-stage kidney disease. Studies in some French regions and in other countries suggest a lower access to the kidney transplant waiting listing and also to kidney transplantation, once waitlisted, for women. Using a mixed methods approach, this study aims to precisely understand these potential sex disparities and their causes. The quantitative study will explore the geographic disparities, compare the determinants of access to the waiting list and to kidney transplantation, and compare the reasons and duration of inactive status on the waiting list in women and men at different scales (national, regional, departmental, and census-block). The qualitative study will allow describing and comparing women’s and men’s views about their disease and transplantation, as well as nephrologists’ practices relative to the French national guidelines on waiting list registration. This type of study is important in the current societal context in which the reduction of sex/gender-based inequalities is a major social expectation. Full article

(This article belongs to the Special Issue Chronic Kidney Disease: Epidemiology and Disparities)

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