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High Performance Functional Bio-Based Polymers for Skin-Contact Products (Volume 2)
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High Performance Functional Bio-Based Polymers for Skin-Contact Products (Volume 2)

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983).

Deadline for manuscript submissions: closed (22 June 2023) | Viewed by 5269

Special Issue Editors

Dr. Serena Danti

E-Mail Website
Guest Editor
1. Department of Civil and Industrial Engineering, University of Pisa, Largo L. Lazzarino 2, 56122 Pisa, Italy
2. Department of Civil and Environmental Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA
Interests: electrospinning; biomaterials; biomedical polymers; piezoelectric materials; smart materials; tissue engineering; advanced in vitro models
Special Issues, Collections and Topics in MDPI journals
Dr. Maria Beatrice Coltelli

E-Mail Website
Guest Editor
Department of Civil and Industrial Engineering, University of Pisa, 56122 Pisa, Italy
Interests: materials science; polymers; biopolymers; bioplastics; bionanocomposites; nanomaterials; reactive processing; recycling; materials waste management
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The personal care, cosmetic and biomedical industries deal with high-value and/or large volume consumption of polymer-based products that are often derived from fossil sources. Although several alternative bio-based polymers have been the subject of recent research, more effort is still needed to increase their specific functionalities and performances in order to proceed with their true translation to the market.

Recently, many researchers have been working in the field of biomaterials with anti-microbial, anti-inflammatory, and anti-oxidant properties, as well as biobased materials, which are renewable and biodegradable. Both types can be transformed into final products by innovative technologies, allowing for the control of bulk or surface properties down to the nanostructure. By merging such biomedical functionalities and environmental aspects, new research could have a great impact on skin-contact biomaterials. The present Special Issue aims to gather research and review papers where the attention paid to health and environmental impact is efficiently integrated, considering both the source and final waste management.

Dr. Serena Danti
Dr. Maria Beatrice Coltelli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biopolymers
  • bioplastics
  • anti-microbial
  • anti-oxidant
  • nanobiotechnology
  • nanofibers
  • skin

Published Papers (2 papers)

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Research

14 pages, 1669 KiB  
Article
Hyaluronic Acid Hydrogel Containing Resveratrol-Loaded Chitosan Nanoparticles as an Adjuvant in Atopic Dermatitis Treatment
by Raffaele Conte, Ilenia De Luca, Anna Valentino, Pierfrancesco Cerruti, Parisa Pedram, Gustavo Cabrera-Barjas, Arash Moeini and Anna Calarco
J. Funct. Biomater. 2023, 14(2), 82; https://0-doi-org.brum.beds.ac.uk/10.3390/jfb14020082 - 31 Jan 2023
Cited by 9 | Viewed by 2823
Abstract
Atopic dermatitis (AD) is a common disease-causing skin inflammation, redness, and irritation, which can eventually result in infection that drastically impacts patient quality of life. Resveratrol (Res) is a natural phytochemical famed for its excellent anti-inflammatory and antioxidant activities. However, it is poorly [...] Read more.
Atopic dermatitis (AD) is a common disease-causing skin inflammation, redness, and irritation, which can eventually result in infection that drastically impacts patient quality of life. Resveratrol (Res) is a natural phytochemical famed for its excellent anti-inflammatory and antioxidant activities. However, it is poorly bioavailable. Thus, a drug delivery system is needed to enhance in vivo bioactivity. Herein, we report the preparation of hyaluronic acid (HA) hydrogels containing resveratrol-loaded chitosan (CS) nanoparticles, their physicochemical analysis, and their potential therapeutic effects in the treatment of AD. Positively charged CS nanoparticles prepared by tripolyphosphate (TPP) gelation showed sizes ranging from 120 to around 500 nm and Res encapsulation efficiency as high as 80%. Embedding the nanoparticles in HA retarded their hydrolytic degradation and also slowed resveratrol release. Resveratrol released from nanoparticle-loaded hydrogel counteracted the oxidative damage induced by ROS generation in TNF-α/INF-γ-treated human keratinocytes (HaCaT) used as an AD in vitro model. Moreover, pre-treatment with Res@gel reduced secretion and gene expression of proinflammatory cytokines in HaCaT cells. The physicochemical analysis and in vitro assay confirmed that the formulated hydrogel could be considered an efficient and sustained resveratrol delivery vector in AD treatment. Full article
(This article belongs to the Special Issue High Performance Functional Bio-Based Polymers for Skin-Contact Products (Volume 2))
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21 pages, 3891 KiB  
Article
Effect of Nanocellulose Types on Microporous Acrylic Acid/Sodium Alginate Super Absorbent Polymers
by Saeed Ismaeilimoghadam, Mehdi Jonoobi, Yahya Hamzeh and Serena Danti
J. Funct. Biomater. 2022, 13(4), 273; https://0-doi-org.brum.beds.ac.uk/10.3390/jfb13040273 - 05 Dec 2022
Cited by 5 | Viewed by 1577
Abstract
The aim of this study was to investigate the effect of different types of nanocellulose, i.e., cellulose nanocrystal (CNC), cellulose nanofiber (CNF) and bacterial nanocellulose (BNC), and also different drying methods (oven-drying and freeze-drying) on the properties of acrylic acid (AA)/sodium alginate (SA) [...] Read more.
The aim of this study was to investigate the effect of different types of nanocellulose, i.e., cellulose nanocrystal (CNC), cellulose nanofiber (CNF) and bacterial nanocellulose (BNC), and also different drying methods (oven-drying and freeze-drying) on the properties of acrylic acid (AA)/sodium alginate (SA) super absorbent polymers (SAPs). In addition, the presence of ammonium per sulfate as an initiator and N-N methylene-bis-acrylamide as a cross-linker were considered. Synthesized SAPs were characterized by Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM). The absorption and rheological properties (i.e., storage modulus and loss modulus) were also investigated. The results of FTIR spectroscopy demonstrated several types of interactions, such as hydrogen and esterification, between SA, AA and nanocellulose. SEM analysis revealed a microporous structure in the SAPs. All SAPs had a centrifuge retention capacity (CRC)/free swelling capacity (FSC) ≥ 69%. The absorption behavior showed that the oven-dried SAPs had superior (about 2×) CRC and FRC in different aqueous media compared to the freeze-dried counterparts. The freeze-dried SAPs showed increased rheological properties in comparison to the oven-dried ones, with SAPs containing BNC and CNC having the highest rheological properties, respectively. Overall, it can be concluded that oven-dried SAPs containing CNC had better absorption properties than the other ones tested in this study. Full article
(This article belongs to the Special Issue High Performance Functional Bio-Based Polymers for Skin-Contact Products (Volume 2))
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