Special Issue "Fighting Multidrug Resistance with Natural Antimicrobials"
Deadline for manuscript submissions: closed (30 June 2019).
Interests: reversal of multidrug resistance in bacteria and cancer cells; efflux pump inhibitors; experimental chemotherapy
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Based on historical evidence, we know that ancient civilizations already used a variety of natural products for the treatment of infectious diseases. Medicinal plants and marine and terrestrial organisms are great sources of natural antimicrobials, furthermore research on natural compounds can open a new horizon in drug discovery in order to find effective antimicrobial agents.
The rapid spread and evolution of bacterial antimicrobial resistance is a major concern regarding the efficacy of antimicrobial therapy, leading to the need to find new antibacterial and resistant modifying agents. Furthermore, the application of natural compounds can decrease or block certain bacterial virulence factors e.g., the inhibition of over-expressed efflux pumps and biofilm production can contribute to successful treatment. A new perspective could be the combination of conventional antibiotics with natural compounds as adjuvants that can overcome resistance and enhance the activity of the antibiotics.
This Special Issue of Microorganisms invites both reviews and original articles that consider natural antimicrobials as potential drug candidates against multidrug resistant microorganisms. Planned topics include: the discovery of natural antibacterial compounds, application of natural compounds in the antimicrobial therapy, natural efflux pump inhibitors, natural anti-biofilm agents, and the combination of conventional antibiotics and natural compounds. You are also welcome to propose a unique topic.
Dr. Gabriella Spengler
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.