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Synthesis and Applications of Natural Polymers and Their Derivatives

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Macromolecular Chemistry".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 772

Special Issue Editors


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Guest Editor
Department of Pharmaceutical Biotechnologies, National Institute for Chemical Pharmaceutical Research and Development–ICCF, 112 Vitan Avenue, 031299 Bucharest, Romania
Interests: microbial polymers; biological synthesis; bioengineering; biomedical applications; bioprocesses; FeS proteins
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Key Laboratory of High-Performance Plastics, Ministry of Education, National and Local Joint Engineering Laboratory for Synthesis Technology of High-Performance Polymers, College of Chemistry, Jilin University, Changchun 130012, China
Interests: high performance polymers

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Guest Editor
Chemical Engineering Department, Faculty of Science, Universidad de Córdoba, Building Marie-Curie, Campus of Rabanales, 14014 Córdoba, Spain
Interests: biorefinery; cellulose; lignin; lignocellulosic residues; nanocellulose; biobased; biomaterials; paper; papermaking; packaging; biocomposites; environmental remediation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Natural polymers have received increasing attention due to their specific advantages, which include the fact that they are obtained from renewable resources, and their biocompatible, biodegradable, generally non-toxic, non-immunogenic, non-carcinogenic, specific physicochemical properties. The most important polymers whose synthesis can be controlled are polysaccharides, polyesters, and proteins from microbial sources (bacteria, microscopic fungi), or macroscopic fungi (mushrooms). The relatively slow and limited rate of production and the complexity of the composition of the organic sources from which they originate, however, represent challenges for those who study their synthesis and purification. However, their useful unique properties, as well as the enormous area of their derivatives (chemically modified, composites), such as sponges, folies, films, fibers, and nanoparticles, and, consequently, the large diversity and importance of potential applications, require researchers’ efforts. From biomedical and pharmaceutical applications (antimicrobial, antitumoral, drug delivery, tissue engineering) to food packaging, technique and the protection of the environment, the full commercial potential of these advancements has yet to be realized in everyday life.

This Special Issue aims to publish original research papers and review articles focusing on the synthesis of natural-based polymers, their derivatives (chemically synthesized, composites), different processing techniques and resulted products, potential applications, and new outlooks.

Dr. Misu Moscovici
Prof. Dr. Guibin Wang
Prof. Dr. Alejandro Rodríguez Pascual
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biological synthesis
  • semisynthetic derivatives
  • polysaccharides and polyhydroxyalkanoates
  • fungal proteins
  • processing techniques
  • composites
  • nanoparticles
  • biomedical
  • pharmaceutical
  • drug delivery systems
  • food protection applications

Published Papers (1 paper)

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Research

15 pages, 783 KiB  
Article
Comprehensive Assessment of Collagen/Sodium Alginate-Based Sponges as Hemostatic Dressings
by Leilei Sun, Yanyan Shen, Mingbo Li, Qiuting Wang, Ruimin Li and Shunmin Gong
Molecules 2024, 29(13), 2999; https://0-doi-org.brum.beds.ac.uk/10.3390/molecules29132999 - 24 Jun 2024
Viewed by 220
Abstract
In our search for a biocompatible composite hemostatic dressing, we focused on the design of a novel biomaterial composed of two natural biological components, collagen and sodium alginate (SA), cross-linked using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide (EDC/NHS) and oxidized sodium alginate (OSA). We conducted a series [...] Read more.
In our search for a biocompatible composite hemostatic dressing, we focused on the design of a novel biomaterial composed of two natural biological components, collagen and sodium alginate (SA), cross-linked using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide (EDC/NHS) and oxidized sodium alginate (OSA). We conducted a series of tests to evaluate the physicochemical properties, acute systemic toxicity, skin irritation, intradermal reaction, sensitization, cytotoxicity, and in vivo femoral artery hemorrhage model. The results demonstrated the excellent biocompatibility of the collagen/sodium alginate (C/SA)-based dressings before and after crosslinking. Specifically, the femoral artery hemorrhage model revealed a significantly shortened hemostasis time of 132.5 ± 12.82 s for the EDC/NHS cross-linked dressings compared to the gauze in the blank group (hemostasis time of 251.43 ± 10.69 s). These findings indicated that C/SA-based dressings exhibited both good biocompatibility and a significant hemostatic effect, making them suitable for biomedical applications. Full article
(This article belongs to the Special Issue Synthesis and Applications of Natural Polymers and Their Derivatives)
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