Pharmaceutical Preparations, Challenges in Formulations and Compatibility Studies

Dear Colleagues,

Compounding pharmacists have always worked to ensure the stability and safety of the compounds they produce, as well as the effectiveness of drugs administered to patients. Several factors can affect the stability of compounded medications, such as heat, light, oxidation or hydrolysis.

In daily routine, pharmacists face some challenges when they have to assess the stability and/or compatibility of drugs in different vehicles. Sometimes there is a lack of information, particularly for novel drugs or new in-house preparations. In the hospital setting, especially for critical care patients, there may be risky situations when the co-administration of drugs or TPN–drug through the same line is required, and no information about their stability is available.

In this sense, further studies are needed to generate more evidence regarding the abovementioned challenges and to increase the knowledge in this area. In this Special Issue, we aim to compile research from experts in the field that focuses on the concerns affecting preparations.

Dr. Pau Riera
Dr. Jan Thomas De Pourcq
Dr. Noe Garin
Guest Editors

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• stability
• sterility
• drug–TPN and drug–drug compatibility
• formulation challenges