Therapeutic Potential of Natural Products in Urolithiasis

Dear Colleagues,

Kidney stones, also called nephrolithiasis or urolithiasis, are one of the most prevalent urological disorders, occasioned by the formation and sporadic movement of crystal agglomerates in the urinary tract. Their movement through the urinary tract can be incredibly painful, leading to medical emergencies. Pharmacological strategies aiming to relieve painful discomfort are primarily based on pain relievers, since there are no effective drugs that act on the dissolution of clusters. Surgical procedures may be required to remove or separate larger stones. In addition, urolithiasis is documented as a risk factor for other systemic ailments, such as cardiovascular and chronic kidney diseases. Considering this, there is an urgent demand for innovative treatments, with those obtained from natural products emphasized, owing to their inestimable supplies of metabolites with substantial therapeutic capacity.

This Special Issue will summarize the advantages of the natural products-based therapies presently investigated for urolithiasis and introduce potential nominees for innovative therapeutic development.

Dr. Priscila de Souza
Guest Editor

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• natural products
• plant extracts
• isolated compounds from medicinal plants
• kidney stone
• nephrolithiasis
• urinary tract
• hypertension
• diabetes
• pain relievers