Antibacterial Applications of Novel Nanoscale Biocompounds

Dear Colleagues,

The emergence of antimicrobial resistance due to the overuse of antimicrobials, together with the existence of naturally untreatable infections, demonstrates the urgent need to discover and generate novel antimicrobials. In this regard, nanotechnology has emerged in recent years as a novel strategy to combat pathogenic microorganisms, offering a viable alternative to conventional antimicrobials with excellent prospects. Investigations into the diagnosis, treatment, and possible prevention of infectious diseases are currently underway with nanostructured materials. Furthermore, the creation of antimicrobial compounds has had a significant positive impact on the food, pharmaceutical, and textile industries, among others. Nevertheless, little is known about their precise method of action, how they affect drug-resistant bacteria, and the dangers involved in using them as antibacterial agents. Antibacterial nanoparticles are safe when used at specified levels, according to many studies, but their effects on beneficial microorganisms—such as humans, animals, and soil microbiota—are a source of worry. At this point, it is important to highlight that nanoscale compounds can be synthesized through biological, physical, and chemical methods. In general, the synthesis of nano-based materials using organisms such as plants, bacteria, fungi, yeasts, and algae is less expensive and safer since it uses eco-friendly, non-toxic materials. Moreover, biogenic nanoformulations are much more stable than those produced by non-green methods due to the natural coating or organic materials on the surface, which prevent agglomeration and uncontrolled growth.

Thus, compiling contemporary research and viewpoints on bio-inspired antimicrobial nanomaterials is the goal of this Special Issue. We seek original research papers, reviews, short reviews, and perspective works that present novel insights or points of view about the use of nanoscale substances in microbiology.

Dr. Francisca Acevedo
Dr. Eulàlia Sans Serramitjana
Guest Editors

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• antimicrobial agent delivery
• biopolymers
• electrospun fibers/scaffolds
• drug–polymer–fiber interactions
• biofilms
• microbial resistance
• antimicrobial nanoparticles
• nanobiomolecules
• nanocoatings
• functionalized nanomaterials