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Polymers
Special Issues
Micro-Nano Spatial Topology for Tissue Engineering and Regenerative Medicine
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Micro-Nano Spatial Topology for Tissue Engineering and Regenerative Medicine

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 4758

Special Issue Editors

Prof. Dr. Guicai Li

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Guest Editor
Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Nantong University, Nantong 226001, China
Interests: biomaterials; micro/nano topology; nerve regeneration; tissue engineering
Prof. Dr. Jianxun Ding

grade E-Mail Website
Guest Editor
Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, China
Interests: polymer chemistry; self-assembly; nanoparticle; hydrogel; scaffold; biomaterial; controlled drug delivery; immunotherapy; regenerative medicine
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Jingan Li

E-Mail Website
Guest Editor
Faculty of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China
Interests: biofabrication; biomodification; micropatterning; tissue regeneration; biodegradable metal
Special Issues, Collections and Topics in MDPI journals
Dr. Rifang Luo

E-Mail Website
Guest Editor
National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China
Interests: surface functionalization; cardiovascular materials; implanted interventional devices; surface and interface; biological tissues

Special Issue Information

Dear Colleagues,

The development of artificial biopolymer implants with a micro-nano spatial topology structure is playing an important role in clinical applications today—for example,  restoring biology function, promoting tissue regeneration, and facilitating wound healing. However, the properties and performance of these artificial biopolymer implants still need to be further improved due to the unpredictable responses of the body to biopolymers and the complicated interactions with the components in living systems. The scope of this Special Issue encompasses new concepts in the preparation and evaluation of artificial biopolymer implants with a micro-nano spatial topology structure, studies into the interaction of this kind of artificial implants with cells, tissues, and the body, and the use of topological biomaterials to answer fundamental biological questions in vitro and in vivo.

Potential topics referring to micro-nano spatial topology structure include but are not limited to the following:

  1. Artificial biopolymer implants;
  2. Cell interaction at the nanoscale and microscale;
  3. Biofunctional treatment for regenerative medicine;
  4. Model systems for cell and tissue studies;
  5. Surface modification for regulating tissue regeneration;
  6. Smart biomaterials;
  7. Biomimetics;
  8. Hydrogel;
  9. Organ-on-chip development;
  10. Cells/signaling mechanism related to guided tissue regeneration;
  11. Investigation methods/modeling for micro-nano spatial topology structure development;
  12. New fabrication techniques and characterization.

Prof. Dr. Guicai Li
Prof. Dr. Jianxun Ding
Prof. Dr. Jingan Li
Dr. Rifang Luo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial implants
  • micro-nano spatial topology
  • regenerative medicine
  • biomaterials
  • cell behavior
  • tissue growth
  • fabrication
  • mechanism

Published Papers (1 paper)

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Review

34 pages, 5667 KiB  
Review
Recent Advances in Silver Nanoparticles Containing Nanofibers for Chronic Wound Management
by Govindaraj Sabarees, Vadivel Velmurugan, Ganesan Padmini Tamilarasi, Veerachamy Alagarsamy and Viswas Raja Solomon
Polymers 2022, 14(19), 3994; https://0-doi-org.brum.beds.ac.uk/10.3390/polym14193994 - 23 Sep 2022
Cited by 17 | Viewed by 4177
Abstract
Infections are the primary cause of death from burns and diabetic wounds. The clinical difficulty of treating wound infections with conventional antibiotics has progressively increased and reached a critical level, necessitating a paradigm change for enhanced chronic wound care. The most prevalent bacterium [...] Read more.
Infections are the primary cause of death from burns and diabetic wounds. The clinical difficulty of treating wound infections with conventional antibiotics has progressively increased and reached a critical level, necessitating a paradigm change for enhanced chronic wound care. The most prevalent bacterium linked with these infections is Staphylococcus aureus, and the advent of community-associated methicillin-resistant Staphylococcus aureus has posed a substantial therapeutic challenge. Most existing wound dressings are ineffective and suffer from constraints such as insufficient antibacterial activity, toxicity, failure to supply enough moisture to the wound, and poor mechanical performance. Using ineffective wound dressings might prolong the healing process of a wound. To meet this requirement, nanoscale scaffolds with their desirable qualities, which include the potential to distribute bioactive agents, a large surface area, enhanced mechanical capabilities, the ability to imitate the extracellular matrix (ECM), and high porosity, have attracted considerable interest. The incorporation of nanoparticles into nanofiber scaffolds constitutes a novel approach to “nanoparticle dressing” that has acquired significant popularity for wound healing. Due to their remarkable antibacterial capabilities, silver nanoparticles are attractive materials for wound healing. This review focuses on the therapeutic applications of nanofiber wound dressings containing Ag-NPs and their potential to revolutionize wound healing. Full article
(This article belongs to the Special Issue Micro-Nano Spatial Topology for Tissue Engineering and Regenerative Medicine)
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