Viruses and Autoimmunity
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Animal Viruses".
Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 16481
Special Issue Editors
Interests: innate immunity; DNA sensors; tumor viruses
Interests: autoimmunity; autoimmune disease; cellular biology; molecular biology; cellular pathways; self-tolerance; molecular mechanisms; pathogenesis; therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
A large body of evidence suggests that several factors are involved in the induction or exacerbation of autoimmune diseases.These include the genetic profile of the individual along with environmental triggers such as infectious agents. Chronic inflammatory responses to infections have indeed been associated with the initiation and exacerbation of autoimmune diseases. In this context, viruses usually trigger a potent innate and adaptative immune response needed to limit the infection. In some instances, however, a deficiency in the control of this immune response may lead to harmful immune reactions directed against the self antigens. The autoimmune attack can be executed through different mechanisms of the immune response including molecular mimicry, bystander activation, and epitope spreading among others. In addition, the immune response may trigger an exaggerated inflammatory reaction which by itself is dangerous for the tissues mimicking the clinical picture reported in the so-called auto-inflammatory diseases. Thus, the aim of this Special Issue is to give an overall picture about the involvement of viral infections in triggering or exacerbating autoimmune/autoinflammatory diseases. To this purpose, we welcome the submission of research articles, review articles and short communications related to all aspects of virus-host interaction, therapy and prevention of autoimmune/auto-inflammatory diseases.
Prof. Dr. Santo Landolfo
Prof. Dr. Pier Luigi Meroni
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- viruses
- viral infections
- antiviral immunity
- innate and adaptive immunity
- autoimmune diseases
- autoinflammatory diseases