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Review

Recent Advances in Fiber–Hydrogel Composites for Wound Healing and Drug Delivery Systems

Centre for Textile Science and Technology (2C2T), Department of Textile Engineering, University of Minho, Campus of Azurém, 4800-058 Guimarães, Portugal
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Author to whom correspondence should be addressed.
Academic Editor: Serena Riela
Received: 29 January 2021 / Revised: 23 February 2021 / Accepted: 25 February 2021 / Published: 2 March 2021
In the last decades, much research has been done to fasten wound healing and target-direct drug delivery. Hydrogel-based scaffolds have been a recurrent solution in both cases, with some reaching already the market, even though their mechanical stability remains a challenge. To overcome this limitation, reinforcement of hydrogels with fibers has been explored. The structural resemblance of fiber–hydrogel composites to natural tissues has been a driving force for the optimization and exploration of these systems in biomedicine. Indeed, the combination of hydrogel-forming techniques and fiber spinning approaches has been crucial in the development of scaffolding systems with improved mechanical strength and medicinal properties. In this review, a comprehensive overview of the recently developed fiber–hydrogel composite strategies for wound healing and drug delivery is provided. The methodologies employed in fiber and hydrogel formation are also highlighted, together with the most compatible polymer combinations, as well as drug incorporation approaches creating stimuli-sensitive and triggered drug release towards an enhanced host response. View Full-Text
Keywords: fiber–hydrogel composite; biodegradable polymers; skin regeneration; drug delivery platforms; controlled release fiber–hydrogel composite; biodegradable polymers; skin regeneration; drug delivery platforms; controlled release
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MDPI and ACS Style

Teixeira, M.O.; Antunes, J.C.; Felgueiras, H.P. Recent Advances in Fiber–Hydrogel Composites for Wound Healing and Drug Delivery Systems. Antibiotics 2021, 10, 248. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics10030248

AMA Style

Teixeira MO, Antunes JC, Felgueiras HP. Recent Advances in Fiber–Hydrogel Composites for Wound Healing and Drug Delivery Systems. Antibiotics. 2021; 10(3):248. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics10030248

Chicago/Turabian Style

Teixeira, Marta O., Joana C. Antunes, and Helena P. Felgueiras 2021. "Recent Advances in Fiber–Hydrogel Composites for Wound Healing and Drug Delivery Systems" Antibiotics 10, no. 3: 248. https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics10030248

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