Special Issue "Biomimetic Sensors and Their Applications"

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: 15 February 2022.

Special Issue Editors

Prof. Dr. Cecilia Cristea
E-Mail Website
Guest Editor
Analytical Chemistry Department, Faculty of Pharmacy, "Iuliu Haţieganu" University of Medicine and Pharmacy 4, Louis Pasteur St., Cluj-Napoca, 400349 Cluj, Romania
Interests: electrochemical and optical sensors; graphene; nanomaterials based electrodes; bioanalysis
Special Issues, Collections and Topics in MDPI journals
Dr. Pooyan Makvandi
E-Mail Website
Guest Editor
Istituto Italiano di Tecnologia, Centre for Materials Interface, viale Rinaldo Piaggio 34, 56025 Pontedera, Pisa, Italy
Interests: nanomaterials; antimicrobial compounds; tissue regeneration; hydrogels; smart materials; microneedles
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are very pleased to invite you to contribute to this Special Issue on biomimetic sensors, which are emerging research subjects with various applications: from the biomedical field (from early diagnosis to therapy monitoring) to food quality control and forensic and environmental analyses.

The field of biomimetic sensors refers to all sensors that use biomimetic elements or biomimetic approaches. The use of aptamers (synthetic nucleic acids or peptides ligands that bind to a specific target) or molecularly imprinted polymers (a class of engineered materials having the role of artificial receptors with a predetermined selectivity for a given target analyte) in biosensors design has successfully replaced natural bioelements, which have limitations and drawbacks. Both aptamers and molecularly imprinted polymers could also be defined as synthetic receptors that mimic natural recognized entities.

Biomimetic means biologically inspired; therefore, focusing on bioinspired materials or processes that mimic biological functions and processes, from the human senses to more complicated pathways, this Special Issue is addressed to a wide audience: electrochemists, physicists, biologists, immunologists, materials specialists, etc.

This Special Issue plans not only to provide an overview on recent achievements but also to stimulate ideas about the current and future research in the biomimetic sensors field. Both original papers and reviews are welcome.

Prof. Dr. Cecilia Cristea
Dr. Pooyan Makvandi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aptamers
  • molecular imprinted polymers
  • e-tongue
  • e-nose
  • sensors arrays
  • bioinspired materials
  • cell and tissue sensors

Published Papers (2 papers)

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Research

Article
Enhancement of the Peroxidase-Like Activity of Iodine-Capped Gold Nanoparticles for the Colorimetric Detection of Biothiols
Biosensors 2020, 10(9), 113; https://0-doi-org.brum.beds.ac.uk/10.3390/bios10090113 - 01 Sep 2020
Cited by 4 | Viewed by 1703
Abstract
A colorimetric assay was developed for the detection of biothiols, based on the peroxidase-like activity of iodine-capped gold nanoparticles (AuNPs). These AuNPs show a synergetic effect in the form of peroxidase-mimicking activity at the interface of AuNPs, while free AuNPs and iodine alone [...] Read more.
A colorimetric assay was developed for the detection of biothiols, based on the peroxidase-like activity of iodine-capped gold nanoparticles (AuNPs). These AuNPs show a synergetic effect in the form of peroxidase-mimicking activity at the interface of AuNPs, while free AuNPs and iodine alone have weak catalytic properties. Thus, iodine-capped AuNPs possess good intrinsic enzymatic activity and trigger the oxidation of 3,3’,5,5’-tetramethylbenzidine (TMB), leading to a change in color from colorless to yellow. When added to solution, biothiols, such as cysteine, strongly bind to the interface of AuNPs via gold-thiol bonds, inhibiting the catalytic activity of AuNPs, resulting in a decrease in oxidized TMB. Using this strategy, cysteine could be linearly determined, at a wide range of concentrations (0.5 to 20 μM), with a detection limit of 0.5 μM using UV-Vis spectroscopy. This method was applied for the detection of cysteine in diluted human urine. Full article
(This article belongs to the Special Issue Biomimetic Sensors and Their Applications)
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Article
Competitive HRP-Linked Colorimetric Aptasensor for the Detection of Fumonisin B1 in Food based on Dual Biotin-Streptavidin Interaction
Biosensors 2020, 10(4), 31; https://0-doi-org.brum.beds.ac.uk/10.3390/bios10040031 - 30 Mar 2020
Cited by 10 | Viewed by 3389
Abstract
Fumonisin B1 (FB1) is the most prevalent and toxic form among fumonisin homologues which are produced by fusarium species and it contaminates various types of food products, posing serious health hazards for humans and animals. In this work, a colorimetric assay for the [...] Read more.
Fumonisin B1 (FB1) is the most prevalent and toxic form among fumonisin homologues which are produced by fusarium species and it contaminates various types of food products, posing serious health hazards for humans and animals. In this work, a colorimetric assay for the detection of FB1 has been developed based on competitive horseradish peroxidase (HRP)-linked aptamer and dual biotin-streptavidin interaction. In short, a biotinylated aptamer of FB1 was immobilized on the microplate by biotin-streptavidin binding; the complementary strand (csDNA) of the aptamer was ligated with HRP by biotin-streptavidin binding again to form a csDNA-HRP sensing probe, competing with FB1 to bind to the aptamer. The color change can be observed after the addition of chromogenic and stop solution, thereby realizing the visual detection of FB1. Under optimal conditions, good linearity was observed within the concentration range of 0.5 to 300 ng/mL, with a detection of limit of 0.3 ng/mL. This assay is further validated by spike recovery tests towards beer and corn samples, it provides a simple, sensitive and reliable method for the screening of FB1 in food samples and may be potentially used as an alternative to conventional assays. Full article
(This article belongs to the Special Issue Biomimetic Sensors and Their Applications)
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