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Hazardous Compounds in Emerging Tobacco Products
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Hazardous Compounds in Emerging Tobacco Products

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Toxicology and Public Health".

Deadline for manuscript submissions: closed (26 June 2023) | Viewed by 2316

Special Issue Editor

Dr. Maciej Goniewicz

E-Mail Website
Guest Editor
Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA
Interests: toxicants in tobacco products; testing tobacco products; emerging tobacco products; health risk of using various types of tobacco products
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Although the combustible cigarette has been the dominant form of nicotine use throughout modern history, the global market of tobacco products is changing and expanding. The introduction of electronic inhalable products, such as nicotine vaping products (NVPs) and heated tobacco products (HTPs), has significantly diversified the nicotine market landscape. Both product types involve electronic devices that produce inhalable nicotine-containing aerosols, but do not rely on combustion to do so. Nicotine can also be delivered orally, and novel oral nicotine products (ONP) that do not contain tobacco leaf material (eg, pouches, lozenges, dissolvable tablets) have recently been introduced on the market. Research on chemistry and toxicity of specific products to inform consumers and aid regulatory decisions is lacking. Emerging tobacco products, by virtue of their highly engineered construction (plastics and glass elements, ceramic or metal heating elements, batteries and electronic components, nicotine solvents and carriers, synthetic flavorings and additives), may contain and emit a number of chemicals of concern. Papers evaluating the presence of potential toxicants in emerging tobacco products (including, but not limited to NVPs, HTPs, and ONPs), are invited for this Special Issue. Since current debate regarding the safety of emerging tobacco products is focused on the toxicants known to be present in cigarettes, we invite papers that compare toxicant levels between conventional and new products. We also invite papers that identify novel toxicants that may be absent in conventional tobacco products. Papers dealing with new approaches to test emerging tobacco products in laboratory settings are also welcome. Finally, we invite papers that assess toxicant exposure in persons who use emerging tobacco products. 

Disclaimer: We will not accept research funded in part or full by any tobacco companies in this Special Issue. For more details, please check: https://0-www-mdpi-com.brum.beds.ac.uk/1660-4601/15/12/2831/htm.

Dr. Maciej Goniewicz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • emerging tobacco products
  • electronic nicotine delivery systems
  • electronic cigarettes
  • e-cigarettes
  • heated tobacco products
  • heat-not-burn
  • tobacco
  • nicotine
  • tobacco ingredients
  • biomarkers

Published Papers (1 paper)

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Research

16 pages, 1831 KiB  
Article
Chemical Elements, Flavor Chemicals, and Nicotine in Unused and Used Electronic Cigarettes Aged 5–10 Years and Effects of pH
by Monique Williams, Wentai Luo, Kevin McWhirter, Omeka Ikegbu and Prue Talbot
Int. J. Environ. Res. Public Health 2022, 19(24), 16931; https://0-doi-org.brum.beds.ac.uk/10.3390/ijerph192416931 - 16 Dec 2022
Cited by 5 | Viewed by 2062
Abstract
The concentrations of elements/metals, nicotine, flavor chemicals and acids were compared in the e-liquids of unused and used first-generation electronic cigarettes (ECs) that were stored for 5–10 years. Metal analysis was performed using inductively coupled plasma optical emission spectroscopy; nicotine and flavor chemical [...] Read more.
The concentrations of elements/metals, nicotine, flavor chemicals and acids were compared in the e-liquids of unused and used first-generation electronic cigarettes (ECs) that were stored for 5–10 years. Metal analysis was performed using inductively coupled plasma optical emission spectroscopy; nicotine and flavor chemical analyses were performed using gas chromatography/mass spectroscopy. Of the 22 elements analyzed, 10 (aluminum, chromium, copper, iron, lead, nickel, selenium, silicon, tin, zinc) were often found in the e-liquids. Five elements had the highest average concentrations: copper (1161.6 mg/L), zinc (295.8 mg/L), tin (287.6 mg/L), nickel (71.1 mg/L), and lead (50.3 mg/L). Nicotine concentrations were always lower than label concentrations indicated. Of the 181 flavor chemicals analyzed, 11 were detected in at least one sample, with hydroxyacetone being present in all samples. In used products, some flavor chemicals appeared to be by-products of heating. E-liquids with the highest concentrations of acids and the lowest pH levels also had the highest concentrations of elements/metals. Metal concentrations in e-liquids increased after use in some products, and some metal concentrations, such as nickel, were high enough to be a health concern. Leachates from discarded ECs could contribute toxic metals/chemicals to the environment, supporting the need for better regulation of atomizer design, composition, and disposal. Full article
(This article belongs to the Special Issue Hazardous Compounds in Emerging Tobacco Products)
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